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Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study
ConclusionDiabetes mellitus history, pre-stroke mRS, longer last known well-to-puncture time, lack of modified thrombolysis in cerebral infarction = 3, and the number of mechanical thrombectomy passes are the predictors of FENI. Future large-scale studies are required to validate these findings.
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Increased Two-Hour Post-Load Plasma Glucose Fluctuation Corresponds with Worse Clinical Prognoses among Acute Ischemic Stroke Patients without a History of Diabetes Mellitus
Conclusion: 2hPG-FPG is a relatively specific indicator of poorer 1-year clinical prognoses among AIS patients, independent of NDDM, 2hPG, and FPG post-hospital admission. Therefore, the oral glucose tolerance test could be a useful approach for detecting a higher likelihood for developing poorer prognoses among patients without DM history.Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 9, 2023 Category: Neurology Source Type: research

High serum amyloid A predicts risk of cognitive impairment after lacunar infarction: Development and validation of a nomogram
ConclusionThe increased SAA is associated with PSCI in lacunar infarction patients, and the nomogram developed with SAA can increase prognostic information for the early detection of PSCI.
Source: Frontiers in Neurology - August 24, 2022 Category: Neurology Source Type: research

Association between diabetes duration and 1 ‐year prognosis of stroke: A national registry study
ConclusionsLong-term diabetes duration ( ≥8 years), but not short-term diabetes duration, was associated with an increased risk of 1-year stroke recurrence in patients with ischemic stroke or TIA.
Source: Brain and Behavior - August 9, 2022 Category: Neurology Authors: Yanli Zhang, Aoming Jin, Xia Meng, Mengxing Wang, Hao Li, Yuesong Pan, Yongjun Wang Tags: ORIGINAL ARTICLE Source Type: research

How do cardiovascular risk factors correlate with post-stroke cognitive function: Directly or indirectly through stroke severity?
ConclusionThis is the first Chinese study exploring the moderated and mediating associations between cardiovascular risk factors, stroke severity, and cognitive function after stroke. Age, female sex, and atrial fibrillation were directly associated with lower cognition after stroke. The combination of hypertension might have a positive effect on cognition.
Source: Frontiers in Neurology - August 5, 2022 Category: Neurology Source Type: research

A score to predict the stroke recurrence of patients with embolic stroke of undetermined source
ConclusionThe developed score can improve risk stratification after ESUS in secondary care settings.
Source: Journal of Neurology - August 4, 2022 Category: Neurology Source Type: research

The role of hypertension and diabetes mellitus on the etiology of middle cerebral artery disease
ConclusionHypertension and diabetes mellitus are related with the different etiology of MCA disease.
Source: Brain and Behavior - March 21, 2022 Category: Neurology Authors: Changqing Zhang, Zixiao Li, Liping Liu, Yuehua Pu, Xinying Zou, Hongyi Yan, Yuesong Pan, Xingquan Zhao, Yilong Wang, Yongjun Wang Tags: ORIGINAL ARTICLE Source Type: research

Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies
This study aimed to identify independent risk factors for first occurrence of stroke in Chinese individuals based on prospective cohort studies. Forty prospective cohort studies assessing 1,984,552 individuals were selected for the final meta-analysis. The identified risk factors for stroke in the Chinese population included old age (RR = 1.86, 95%CI: 1.47–2.36), hypertension (RR = 2.76, 95%CI: 2.26–3.37), cardiovascular disease history (RR = 1.98, 95%CI: 1.06–3.69), chronic kidney disease (RR = 1.65, 95%CI: 1.36–2.01), diabetes mellitus (RR = 1.71, 95%CI: 1.34–2.18), metabolic syndrome (RR = 1.59, 95%CI: 1.33–...
Source: Frontiers in Neurology - March 18, 2022 Category: Neurology Source Type: research

Development and Validation of a Nomogram to Predict the Individual Future Stroke Risk for Adult Patients With Moyamoya Disease: A Multicenter Retrospective Cohort Study in China
Conclusions: We developed a novel nomogram incorporating several clinical characteristics with relatively good accuracy, which may have considerable potential for evaluating individual future stroke risk and providing useful management recommendations for adult patients with MMD in clinical practice.
Source: Frontiers in Neurology - May 13, 2021 Category: Neurology Source Type: research

An Analysis of the Potential Relationship of Triglyceride Glucose and Body Mass Index With Stroke Prognosis
Conclusion: Overweight/obese patients with ischemic stroke have better survival than patients with low/normal weight. The association of BMI and stroke outcome is not changed by TYG index.
Source: Frontiers in Neurology - April 22, 2021 Category: Neurology Source Type: research

Relationship Between Glycosylated Hemoglobin and Short-Term Mortality of Spontaneous Intracerebral Hemorrhage
Conclusions: Therefore, we concluded that low or extremely low HbA1c levels (≤5.10%) after stroke were associated with higher short-term mortality in SICH patients, with or without DM.
Source: Frontiers in Neurology - April 16, 2021 Category: Neurology Source Type: research

Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke
Conclusions: Concurrency of early-age famine exposure and diabetes mellitus was associated with a higher risk of stroke recurrence within 12 months, and adherence to evidence-based KPI did not reduce the risk significantly.
Source: Frontiers in Neurology - January 20, 2021 Category: Neurology Source Type: research

Stress Hyperglycemia and Outcome of Non-diabetic Patients After Acute Ischemic Stroke
Conclusion: Stress hyperglycemia, measured by glucose-to-HbA1c ratio, was related to an elevated risk of stroke recurrence and all-cause death in patients with acute ischemic stroke but without diabetes.
Source: Frontiers in Neurology - September 17, 2019 Category: Neurology Source Type: research

Inpatient statin use and stroke recurrence in patients with or without diabetes mellitus.
Conclusion: Inpatient statin use was associated with lower stroke recurrence in non-diabetic patients after acute ischaemic stroke, but no definite association between inpatient statin use and stroke recurrence in patients with diabetes mellitus was found. PMID: 31328681 [PubMed - as supplied by publisher]
Source: Neurological Research - July 23, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

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