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Specialty: Geriatrics
Condition: Dementia

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Total 327 results found since Jan 2013.

Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia
DiscussionThe use of AChEIs in people with dementia may be associated with reduced risk of ischemic stroke and death. These results call for a closer examination of the cardiovascular effects of AChEIs.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 10, 2018 Category: Geriatrics Source Type: research

Prevalence of Chronic Cancer and No-Cancer Pain in Elderly Hospitalized Patients: Elements for the Early Assessment of Palliative Care Needs
ConclusionPain is a critical underestimated problem in elderly patients. A timely systematic evaluation of the pain would call attention to palliative care needs and reduce the negative effects of uncontrolled pain on the quality of life.
Source: International Journal of Gerontology - July 5, 2018 Category: Geriatrics Source Type: research

Increased risk for dementia both before and after stroke: A population-based study in women followed over 44 years
DiscussionThere is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 5, 2018 Category: Geriatrics Source Type: research

Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia
DiscussionThe use of AChEIs in people with dementia may be associated with reduced risk of ischemic stroke and death. These results call for a closer examination of the cardiovascular effects of AChEIs.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 5, 2018 Category: Geriatrics Source Type: research

Increased risk for dementia both before and after stroke: A population-based study in women followed over 44  years
Discussion There is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - June 22, 2018 Category: Geriatrics Source Type: research

The association between relevant comorbidities and dementia in patients with atrial fibrillation
AbstractRisk of dementia is increased in patients with atrial fibrillation (AF). We aimed to  study associations between relevant comorbidities and prevalent as well as incident dementia in AF patients. Study population included all adults (n = 12,283) ≥ 45 years diagnosed with AF at 75 primary care centers in Sweden 2001–2007. Logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (95% CI) for associations between comorbidities and prevalent dementia. In a subsample (n = 12,096), (excluding patients with dementia diagnosed before AF onset), Cox regression was used to esti...
Source: AGE - June 22, 2018 Category: Geriatrics Source Type: research

Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia
Discussion The use of AChEIs in people with dementia may be associated with reduced risk of ischemic stroke and death. These results call for a closer examination of the cardiovascular effects of AChEIs.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - May 18, 2018 Category: Geriatrics Source Type: research

Lower Plasma Klotho Concentrations Are Associated with Vascular Dementia but Not Late-Onset Alzheimer ’s Disease
Conclusion: In a sample of elderly individuals, we found a significant association between low plasma Klotho levels and VD, but not LOAD. This finding suggests that, although these 2 forms of dementia might overlap, some physiopathological mechanisms related to VD and LOAD remain distinct.Gerontology
Source: Gerontology - May 16, 2018 Category: Geriatrics Source Type: research

Neurologic manifestations of elderly patients with cancer.
CONCLUSION: Identifying the frequency and correlation of neurologic manifestations in older cancer patients will allow for the implementation of timely multidisciplinary care in an attempt to improve these patients' health-related quality of life. PMID: 29704209 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - April 27, 2018 Category: Geriatrics Authors: Cacho-Díaz B, Lorenzana-Mendoza NA, Reyes-Soto G, Ávila-Funes JA, Navarrete-Reyes AP Tags: Aging Clin Exp Res Source Type: research

Depression in type 1 diabetes and risk of dementia.
CONCLUSIONS: For people with T1D, depression significantly increases dementia risk. Given the pervasiveness of depression in T1D, this has major implications for successful aging in this population recently living to old age. PMID: 29634288 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - April 10, 2018 Category: Geriatrics Authors: Gilsanz P, Schnaider Beeri M, Karter AJ, Quesenberry CP, Adams AS, Whitmer RA Tags: Aging Ment Health Source Type: research

108appropriate anticoagulation in older adults with atrial fibrillation
Introduction: Anticoagulation is recommended to prevent stroke in atrial fibrillation. NICE Guidelines state anticoagulation should be offered to all patients with a CHADVASC of 2 and above. The ESC (European Society of Cardiology) guidelines advise falls and advanced dementia should not prevent patients from receiving anticoagulation. Furthermore, advanced age (above 75 or 80 years old) should not mean anticoagulation is withheld, especially as the risk of ischaemic stroke increases with age and comorbidities.
Source: Age and Ageing - March 27, 2018 Category: Geriatrics Source Type: research

2018 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disease process, in the stage of mild cognitive impairment due to Alzheimer's disease. An estimated 5.7 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States is projected to grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2015, o...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 20, 2018 Category: Geriatrics Source Type: research

Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low ‐ and Middle‐Income Countries
ConclusionThese results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.
Source: Journal of the American Geriatrics Society - February 10, 2018 Category: Geriatrics Authors: Ai Koyanagi, Elvira Lara, Brendon Stubbs, Andre F. Carvalho, Hans Oh, Andrew Stickley, Nicola Veronese, Davy Vancampfort Tags: Clinical Investigation Source Type: research

Prevalence of Chronic Cancer and No-Cancer Pain in Elderly Hospitalized Patients: Elements for the Early Assessment of Palliative Care Needs
Conclusion Pain is a critical underestimated problem in elderly patients. A timely systematic evaluation of the pain would call attention to palliative care needs and reduce the negative effects of uncontrolled pain on the quality of life.
Source: International Journal of Gerontology - February 9, 2018 Category: Geriatrics Source Type: research