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Condition: Diabetes Type 1
Drug: Insulin
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Total 55 results found since Jan 2013.
How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke.
“Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news
How dysregulation of the immune system promotes diabetes mellitus and cardiovascular risk complications
Front Cardiovasc Med. 2022 Sep 29;9:991716. doi: 10.3389/fcvm.2022.991716. eCollection 2022.ABSTRACTDiabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin resistance or failure to produce insulin. Patients with DM develop microvascular complications that include chronic kidney disease and retinopathy, and macrovascular complications that mainly consist in an accelerated and more severe atherosclerosis compared to the general population, increasing the risk of cardiovascular (CV) events, such as stroke or myocardial infarction by 2- to 4-fold. DM is commonly associate...
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Diane Girard Claire Vandiedonck Source Type: research
People With Diabetes Are More Vulnerable to Heart Disease. How to Reduce the Risk
If you’ve been diagnosed with diabetes, know that you’ve got plenty of company. The American Diabetes Association (ADA) reports that in 2019, the most recent year for which data is available, 37.3 million adults in the U.S.—about 11.3% of the population—had the chronic condition, and that number continues to grow.
Type 1 diabetes develops when the body isn’t able to produce insulin, and Type 2 occurs when the body doesn’t use insulin correctly. Type 2 is the most common form of diabetes, and when it’s uncontrolled, a person’s blood sugar can jump to dangerous levels that requ...
Source: TIME: Health - July 20, 2022 Category: Consumer Health News Authors: Elaine K. Howley Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news
The Truth About Fasting and Type 2 Diabetes
Most fad diets don’t live up to the hype, let alone serious scientific scrutiny. But intermittent fasting seems to be an exception. These plans involve going without caloric foods or drinks for an extended period of time—anywhere from 16 hours to several days—and they have become increasingly popular. Research has also found them to be effective for weight loss.
Doctors often advise people with Type 2 diabetes to lose weight, which can have beneficial effects on blood glucose and insulin sensitivity, as well as on the progression of the disease. For this and other reasons, experts are actively looking at ...
Source: TIME: Health - June 16, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Diet & Nutrition freelance healthscienceclimate Source Type: news
Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy
Biosci Rep. 2022 Mar 31;42(3):BSR20212209. doi: 10.1042/BSR20212209.ABSTRACTDiabetes mellitus is a chronic metabolic disease that occurs when the pancreas is not producing enough insulin or when the insulin that it does produce is not able to be used effectively in the body. This results in hyperglycemia and if the blood sugars are not controlled, then it can lead to serious damage of various body systems, especially the nerves and the blood vessels. Uncontrolled diabetes is a major cause of kidney failure, heart attacks, stroke and amputation. One of the most devastating complications for patients is diabetic retinopathy ...
Source: Bioscience Reports - March 2, 2022 Category: Biomedical Science Authors: Jennifer Matthews Lakshini Herat Jennifer Rooney Elizabeth Rakoczy Markus Schlaich Vance B Matthews Source Type: research
Complications of diabetes and metrics of glycaemic management derived from continuous glucose monitoring
CONCLUSIONS: The evidence supports the association between diabetes complications and CGM-derived measures of intra-day glycaemic variability. TIR emerged as the most consistent measure, supporting its emerging role in clinical practice. More longitudinal studies and trials are required to confirm these associations, particularly for type 1 diabetes where there are limited data.PMID:35094087 | DOI:10.1210/clinem/dgac034
Source: The Journal of Clinical Endocrinology and Metabolism - January 30, 2022 Category: Endocrinology Authors: Michael Yapanis Steven James Maria E Craig David O'Neal Elif I Ekinci Source Type: research
Diabetes Equates the Rich and the Poor
Diabetes test, Mauritius. Credit: Nasseem Ackbarally/IPSBy Bruno KappaNAIROBI, Nov 12 2021 (IPS) Although for different reasons, diabetes appears to be one of the few cases that put rich and poor societies at equal footing. In either case, diabetes is caused by wrong, dangerous to health nutritional habits.
In fact, people in industrialised countries tend to consume the so-called “junk food”, while in poor nations diabetes is caused by malnutrition and undernourishment.
And it is a seriously worrying health problem. In fact, globally, an estimated 422 million adults were living with diabetes as of 2014, compared to 108...
Source: IPS Inter Press Service - Health - November 12, 2021 Category: International Medicine & Public Health Authors: Bruno Kappa Tags: Global Headlines Health Source Type: news
Novel Reclassification of Adult Diabetes Is Useful to Distinguish Stages of β-Cell Function Linked to the Risk of Vascular Complications: The DOLCE Study From Northern Ukraine
ConclusionThe novel reclassification algorithm of patients with adult diabetes was reproducible in this population from northern Ukraine. It may be beneficial for the patients in the SIDD subgroup to initiate earlier insulin treatment or other anti-diabetic modalities to preserve β-cell function. Long-term diabetes cases with preserved β-cell function and lower risk for microvascular complications represent an interesting subgroup of patients for further investigations of protective mechanisms.
Source: Frontiers in Genetics - July 2, 2021 Category: Genetics & Stem Cells Source Type: research
(Ultra-)long-acting insulin analogues for people with type 1 diabetes mellitus
CONCLUSIONS: Comparing insulin detemir with NPH insulin for T1DM showed lower risk of severe hypoglycaemia in favour of insulin detemir (moderate-certainty evidence). However, the 95% prediction interval indicated inconsistency in this finding. Both insulin detemir and insulin glargine compared with NPH insulin did not show benefits or harms for severe nocturnal hypoglycaemia. For all other main outcomes with overall low risk of bias and comparing insulin analogues with each other, there was no true beneficial or harmful effect for any intervention. Data on patient-important outcomes such as QoL, macrovascular and microvas...
Source: Cochrane Database of Systematic Reviews - March 4, 2021 Category: General Medicine Authors: Bianca Hemmingsen Maria-Inti Metzendorf Bernd Richter Source Type: research
Genes, Vol. 11, Pages 1256: Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity
Conclusion: This study presents a platform to discover potential targets for diabesity treatment and helps in understanding the molecular mechanism.
Source: Genes - October 25, 2020 Category: Genetics & Stem Cells Authors: Udhaya Kumar S Bithia Rajan Thirumal Kumar D Anu Preethi V Taghreed Abunada Salma Younes Sarah Okashah Selvarajan Ethiraj George Priya Doss C Hatem Zayed Tags: Article Source Type: research
Stroke in the patient with diabetes (part 1) – Epidemiology, etiology, therapy and prognosis
There is a higher incidence of stroke in both the type 2 diabetic and the non-diabetic insulin resistant patient which is accompanied by higher morbidity and mortality. The increase in the frequency of stroke is due to an increase in cerebral infarction, mainly lacunar infarcts, with the incidence of cerebral hemorrhage being less frequent. The major risk factors for stroke in the type 2 diabetic patient are age, hypertension, the number of features of the Metabolic Syndrome, the presence of diabetic nephropathy in both the type 1 and type 2 patient, the presence of peripheral and coronary artery disease and especially the...
Source: Diabetes Research and Clinical Practice - May 18, 2020 Category: Endocrinology Authors: David S.H. Bell, Edison Goncalves Tags: Review Source Type: research
Stroke in the patient with diabetes (Part 1) - Epidemiology, etiology, therapy and prognosis
There is a higher incidence of stroke in both the type 2 diabetic and the non-diabetic insulin resistant patient which is accompanied by higher morbidity and mortality. The increase in the frequency of stroke is due to an increase in cerebral infarction, mainly lacunar infarcts, with the incidence of cerebral hemorrhage being less frequent. The major risk factors for stroke in the type 2 diabetic patient are age, hypertension, the number of features of the Metabolic Syndrome, the presence of diabetic nephropathy in both the type 1 and type 2 patient, the presence of peripheral and coronary artery disease and especially the...
Source: Diabetes Research and Clinical Practice - May 18, 2020 Category: Endocrinology Authors: David S.H. Bell, Edison Goncalves Tags: Review Source Type: research
Emerging Targets for Cardiovascular Disease Prevention in Diabetes.
Abstract
Type 1 and type 2 diabetes mellitus (T1DM and T2DM) increase the risk of atherosclerotic cardiovascular disease (CVD), resulting in acute cardiovascular events, such as heart attack and stroke. Recent clinical trials point toward new treatment and prevention strategies for cardiovascular complications of T2DM. New antidiabetic agents show unexpected cardioprotective benefits. Moreover, genetic and reverse translational strategies have revealed potential novel targets for CVD prevention in diabetes, including inhibition of apolipoprotein C3 (APOC3). Modeling and pharmacology-based approaches to improve ins...
Source: Trends in Molecular Medicine - May 14, 2020 Category: Molecular Biology Authors: Stitziel NO, Kanter JE, Bornfeldt KE Tags: Trends Mol Med Source Type: research
