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Specialty: Neurology
Condition: Bleeding

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Total 720 results found since Jan 2013.

Methotrexate induced leucoencephalopathy: A stroke mimic
We describe the case of a 17 year old girl with acute lymphoblastic leukemia, who developed stroke like episodes on two consecutive challenges with a chemotherapeutic regime which included intravenous and intrathecal methotrexate. She had MRI changes consistent with acute ischemic stroke on both occasions. Her deficits recovered completely and spontaneously, as did the MRI changes. She did not have any further episodes when methotrexate was excluded from the chemotherapeutic regime.
Source: Annals of Indian Academy of Neurology - August 26, 2013 Category: Neurology Authors: Tushar D GosaviMohammed Tauqeer AhmadLai-Heng LeeShih-Hui Lim Source Type: research

Pregnancy-associated Intracranial Hemorrhage: Results of a Survey of Neurosurgical Institutes across Japan
Conclusion: Pregnancy-associated hemorrhagic strokes frequently concealed baseline CVDs, especially when they occurred before the 32nd week of gestation. AVMs were the predominant bleeding source. For appropriate treatment, therefore, close examination for cerebral vascular lesions is essential when a pregnancy-associated hemorrhagic stroke is encountered.
Source: Journal of Stroke and Cerebrovascular Diseases - November 18, 2013 Category: Neurology Authors: Jun C. Takahashi, Koji Iihara, Akira Ishii, Eiju Watanabe, Tomoaki Ikeda, Susumu Miyamoto Tags: Original Articles Source Type: research

Predicting intracerebral hemorrhage by baseline magnetic resonance imaging in stroke patients undergoing systemic thrombolysis
ConclusionsIn ischemic stroke patients within 3 h from symptom onset, the existence of FLAIR‐positive lesions on pretreatment MRI is significantly associated with an increased bleeding risk due to systemic thrombolysis. Therefore, considering FLAIR‐positive lesions on baseline MRI might guide treatment decisions in ischemic stroke.
Source: Acta Neurologica Scandinavica - July 18, 2014 Category: Neurology Authors: C. Hobohm, D. Fritzsch, S. Budig, J. Classen, K.‐T. Hoffmann, D. Michalski Tags: Original Article Source Type: research

Gastrointestinal complications after ischemic stroke
Ischemic stroke is an important cause of morbidity and mortality, and currently the leading cause of adult disability in developed countries. Stroke is associated with various non-neurological medical complications, including infections and thrombosis. Gastrointestinal complications after stroke are also common, with over half of all stroke patients presenting with dysphagia, constipation, fecal incontinence or gastrointestinal bleeding. These complications are associated with increased hospital length of stay, the development of further complications and even increased mortality.
Source: Journal of the Neurological Sciences - September 4, 2014 Category: Neurology Authors: Carlos R. Camara-Lemarroy, Beatriz E. Ibarra-Yruegas, Fernando Gongora-Rivera Tags: Review article Source Type: research

Intravenous thrombolysis in a patient with left atrial myxoma with acute ischemic stroke
In this report we describe our experience of IVT in atrial myxoma patient with ischemic stroke and review the relevant literature.
Source: Annals of Indian Academy of Neurology - November 5, 2014 Category: Neurology Authors: Girish Baburao KulkarniRavi YadavVeerendrakumar MustareSailesh Modi Source Type: research

Intravenous Tissue Plasminogen Activator for an Ischemic Stroke with Occult Double Primary Cancer
Discussion: Although systemic thrombolysis with tPA for ischemic stroke in patients with advanced-stage cancer may be performed relatively safely, optimal post-thrombolysis management is important to prevent the complications.Case Rep Neurol 2014;6:238-242
Source: Case Reports in Neurology - November 7, 2014 Category: Neurology Source Type: research

Statistical analysis plan for the ‘Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke’ (TARDIS) trial
DiscussionThis paper and attachment describe the trial's statistical analysis plan, as developed from the protocol during recruitment and prior to unblinding of data. The statistical analysis plan contains design and methods for analyses, and unpopulated tables and figures for the primary and baseline publications. The data from the trial will provide the first large‐scale randomized evidence for the use of intensive antiplatelet therapy for preventing recurrence after acute stroke and transient ischemic attack.
Source: International Journal of Stroke - December 31, 2014 Category: Neurology Authors: Philip M. W. Bath, Katie Robson, Lisa J. Woodhouse, Nikola Sprigg, Robert Dineen, Stuart Pocock, Tags: Protocol Source Type: research

Hemorrhagic stroke, cerebral amyloid angiopathy, Down syndrome and the Boston criteria.
Abstract A stroke, or a cerebrovascular accident (CVA) is a life-threatening condition which often results in permanent or significant disability in the adult population. Several classifications of CVAs exist, one of them being based on the mechanism of injury of brain tissue: ischemic (85-90%) and hemorrhagic (10-15%). In a hemorrhagic stroke an intercranial bleeding occurs, leading to the formation of a focal hematoma typically located in the basal ganglia of the brain (approx. 45% of cases). A common yet underestimated cause of intracerebral hemorrhage is cerebral small vessel disease with microhemorrhages, inc...
Source: Neurologia i Neurochirurgia Polska - May 1, 2015 Category: Neurology Authors: Jastrzębski K, Kacperska MJ, Majos A, Grodzka M, Głąbiński A Tags: Neurol Neurochir Pol Source Type: research

Acute ischemic stroke and abnormal blood hemoglobin concentration
ConclusionsOur results suggest that an elevated HGB on the initial admission is associated with more severe strokes, greater disability at discharge, and higher 30‐day mortality after AIS. A low HGB on admission is associated with longer stay in the acute care hospital.
Source: Acta Neurologica Scandinavica - October 21, 2015 Category: Neurology Authors: J. C. Furlan, J. Fang, F. L. Silver Tags: Original Article Source Type: research

Dual antiplatelet therapy after stroke or transient ischaemic attack – how long to treat? The duration of aspirin plus clopidogrel in stroke or transient ischaemic attack: a systematic review and meta‐analysis
ConclusionsShort‐term DAPT appears to be superior to prolonged DAPT. However, the difference in efficacy outcome needs to be carefully explained and confirmed by further well‐designed randomized controlled trials.
Source: European Journal of Neurology - March 29, 2016 Category: Neurology Authors: F. Ge, H. Lin, Y. Liu, M. Li, R. Guo, Z. Ruan, T. Chang Tags: Original Article Source Type: research

Female Sex, Time in Therapeutic Range, and Clinical Outcomes in Atrial Fibrillation Patients Taking Warfarin Brief Reports
Conclusion— Anticoagulated female patients with atrial fibrillation had a similar rate of cardiovascular death and SSE, but a lower risk of major bleeding, compared with males. TTR (but not female sex) was an independent predictor for combined cardiovascular death and SSE and clinically relevant bleeding events.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Senoo, K., Lip, G. Y. H. Tags: Quality and Outcomes Brief Reports Source Type: research

Standard blood pressure target is sufficient for treating some strokes
An international stroke study found that standard and intensive blood pressure treatments were equally effective in the emergency treatment of acute intracerebral hemorrhage, a type of stroke caused by bleeding into the brain. Patients whose systolic blood pressure was reduced rapidly in emergency rooms to standard levels used to treat acute stroke (140-179 mm Hg) did as well as patients whose pressure was reduced to intensive levels (110-139 mm Hg). The study, published in the New England Journal of Medicine, was funded by the NIH’s National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - June 8, 2016 Category: Neurology Source Type: news

Serum trace elements are associated with hemostasis, lipid spectrum and inflammatory markers in men suffering from acute ischemic stroke
AbstractThe primary objective of the study is investigation of the association between trace elements status and hemostasis, lipid spectrum and inflammatory markers in acute ischemic stroke (AIS). A total of 30 men suffering from AIS and 30 healthy controls were involved in the current survey. Blood count, serum lipid spectrum, complement components C4 and C3a, vascular endothelial growth factor (VEGF), S100B protein, NR2 antibodies (NR2Ab), and total antioxidant status (TAS), as well as plasma fibrinogen, and D-dimer levels and activated partial thromboplastin time (APTT) were assessed. Serum trace elements were analyzed ...
Source: Metabolic Brain Disease - February 19, 2017 Category: Neurology Source Type: research