Filtered By:
Condition: GERD
Education: Study

This page shows you your search results in order of date. This is page number 4.

Order by Relevance | Date

Total 59 results found since Jan 2013.

Patients with Cerebral Stroke Have an Increased Risk of Gastroesophageal Reflux Disease: A Population-Based Cohort Study
This study was designed to investigate the prevalence and risk of gastroesophageal reflux disease (GERD) between patients with stroke and those without stroke in Taiwan.
Source: Journal of Stroke and Cerebrovascular Diseases - January 8, 2018 Category: Neurology Authors: Chen-Shu Chang, Hsuan-Ju Chen, Chun-Hui Liao Source Type: research

Heartburn drugs linked to premature death
Conclusion This larger set of observational data finds that PPI drugs are associated with an increase in the risk of early death compared with either H2 blockers or no acid suppression drugs. This was the case for participants both with and without gastrointestinal problems. It also appears as though the longer the PPIs drugs are taken, the greater the risk of death. Considering that these drugs are widely used in the UK, these findings may cause concern. But the research has a number of important limitations: The study was conducted in a population of mostly white, older US male veterans, which might limit the ability...
Source: NHS News Feed - July 4, 2017 Category: Consumer Health News Tags: Medication Source Type: news

Proton Pump Inhibitors and Dementia Incidence
To the Editor I read with interest the article by Gomm et al investigating the association of proton pump inhibitors and dementia. The authors are to be commended for their large data set, analysis, and detailed proposed pathophysiologic mechanism by which this association might occur. However, 2 important medical comorbidities seem to be missing from their study: gastroesophageal reflux disease and obstructive sleep apnea. Both of these comorbidities can cause cognitive issues, especially in those with apolipoprotein E genetic variants and those who have had a stroke. Gastroesophageal reflux disease would constitute the r...
Source: JAMA Neurology - June 20, 2016 Category: Neurology Source Type: research

PPI Side Effects Destroying Your Blood Vessels
It seems whenever I turn on my TV these days, there’s Larry the Cable Guy with a quick fix for heartburn. He makes it sound so simple. Just pop a pill, eat all the chili dogs you want, and no more heartburn… at least for a couple of weeks. What Is Heartburn? Heartburn is an irritation of the esophagus that is caused by stomach acid. It has nothing to do with the heart. But a new study has found a link between proton-pump inhibitors (PPIs) — heartburn drugs — and the premature aging of blood vessels. Heartburn Drugs PPI Side Effects Researchers focused on the effects of two PPIs, one of which is Nexium. They...
Source: Al Sears, MD Natural Remedies - June 16, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health Source Type: news

Long‐Term Safety of a Coordinated Delivery Tablet of Enteric‐Coated Aspirin 325 mg and Immediate‐Release Omeprazole 40 mg for Secondary Cardiovascular Disease Prevention in Patients at GI Risk
ConclusionsLong‐term treatment with PA32540 once daily for up to 12 months in subjects at risk for aspirin‐associated UGI events is not associated with any new or unexpected safety events.
Source: Cardiovascular Therapeutics - March 3, 2016 Category: Cardiology Authors: Jay L. Goldstein, David J. Whellan, James M. Scheiman, Byron L. Cryer, Glenn M. Eisen, Angel Lanas, John G. Fort Tags: Original Research Article Source Type: research

Link between indigestion drugs and dementia 'inconclusive'
Conclusion This study found people taking PPIs had a 44% higher risk of developing dementia in a seven-year period compared with those not taking the drugs. However, it's not accurate to say this was down to the PPIs – the study couldn't prove this, and there are many possible explanations. For a start, the groups weren't very similar. Those taking PPIs had poorer health, and were more likely to be taking a number of medicines and have conditions linked to a higher risk of dementia, such as diabetes and heart disease. After taking these factors into account in the analysis, the link between PPIs and dementia reduc...
Source: NHS News Feed - February 16, 2016 Category: Consumer Health News Tags: Medication Neurology Older people Source Type: news

Long‐Term Safety of a Coordinated Delivery Tablet of Enteric‐Coated Aspirin 325 mg and Immediate‐Release Omeprazole 40 mg for Secondary Cardiovascular Disease Prevention in Patients at GI Risk
ConclusionsLong‐term treatment with PA32540 once daily for up to 12 months in subjects at risk for aspirin‐associated UGI events is not associated with any new or unexpected safety events. Clinical trials. gov identifier: NCT00995410.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - January 4, 2016 Category: Cardiology Authors: Jay L. Goldstein, David J. Whellan, James M. Scheiman, Byron L. Cryer, Glenn M. Eisen, Angel Lanas, John G. Fort Tags: Original Research Article Source Type: research

Newly diagnosed gastroesophageal reflux disease increased the risk of acute exacerbation of chronic obstructive pulmonary disease during the first year following diagnosis – a nationwide population‐based cohort study
ConclusionThis study demonstrated that GERD is an independent risk factor for AECOPD. Caution should be exercised when assessing GERD symptoms in patients with COPD.
Source: International Journal of Clinical Practice - October 31, 2014 Category: Internal Medicine Authors: Y. H. Lin, C. L. Tsai, L. N. Chien, H. Y. Chiou, C. Jeng Tags: Original Paper Source Type: research

Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort.
CONCLUSIONS: In COPD the presence of physician-diagnosed GERD is associated with increased symptoms, poorer QOL and increased frequency of exacerbations at baseline and during follow-up. These associations are maintained after controlling for PPI use. The PPI-exacerbations association could result from confounding-by-indication. PMID: 24894541 [PubMed - indexed for MEDLINE]
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Martinez CH, Okajima Y, Murray S, Washko GR, Martinez FJ, Silverman EK, Lee JH, Regan EA, Crapo JD, Curtis JL, Hatabu H, Han MK, COPDGene Investigators Tags: Respir Res Source Type: research

Differences in wake‐up and unknown onset stroke examined in a stroke registry
ConclusionWUS has lower rates of ICH but similar stroke severity and outcomes to AOS. UOS prevalence appears to be increasing, with higher stroke severity and worse prognosis.
Source: International Journal of Stroke - October 1, 2014 Category: Neurology Authors: John M. Reid, Dingwei Dai, Bharath Cheripelli, Christine Christian, Yvette Reidy, Gord J. Gubitz, Stephen J. Phillips Tags: Research Source Type: research

Impact of self-reported Gastroesophageal reflux disease in subjects from COPDGene cohort
Background: The coexistence of gastroesophageal reflux disease (GERD) and COPD has been recognized, but there has been no comprehensive evaluation of the impact of GERD on COPD-related health status and patient-centered outcomes. Methods: Cross-sectional and longitudinal study of 4,483 participants in the COPDGene cohort who met GOLD criteria for COPD. Physician-diagnosed GERD was ascertained by questionnaire. Clinical features, spirometry and imaging were compared between COPD subjects without versus with GERD. We evaluated the relationship between GERD and symptoms, exacerbations and markers of microaspiration in univari...
Source: Respiratory Research - June 3, 2014 Category: Respiratory Medicine Authors: Carlos MartinezYuka OkajimaSusan MurrayGeorge WashkoFernando MartinezEdwin SilvermanJin LeeElizabeth ReganJames CrapoJeffrey CurtisHiroto HatabuMeiLan Han Source Type: research

"Impact of self-reported Gastroesophageal reflux disease in subjects from COPDGene cohort"
Background: The coexistence of gastroesophageal reflux disease (GERD) and COPD has been recognized, but there has been no comprehensive evaluation of the impact of GERD on COPD-related health status and patient-centered outcomes. Methods: Cross-sectional and longitudinal study of 4,483 participants in the COPDGene cohort who met GOLD criteria for COPD. Physician-diagnosed GERD was ascertained by questionnaire. Clinical features, spirometry and imaging were compared between COPD subjects without versus with GERD. We evaluated the relationship between GERD and symptoms, exacerbations and markers of microaspiration in univari...
Source: Respiratory Research - June 3, 2014 Category: Respiratory Medicine Authors: Carlos MartinezYuka OkajimaSusan MurrayGeorge WashkoFernando MartinezEdwin SilvermanJin LeeElizabeth ReganJames CrapoJeffrey CurtisHiroto HatabuMeiLan Han Source Type: research

Gastroesophageal Reflux in Chronic Cough and Cough Syncope and the Effect of Antireflux Treatment: Case Report and Literature Review.
CONCLUSION: For chronic cough and cough syncope of unknown cause, the GER assessment could be valuable. In treating well-selected GER-related chronic cough and cough syncope, PPI, SRF, and LF can be considered. Moreover, satisfactory restoration of physical and social functions could be achieved after effective antireflux therapy. PMID: 24842868 [PubMed - as supplied by publisher]
Source: The Annals of Otology, Rhinology, and Laryngology - May 19, 2014 Category: ENT & OMF Authors: Hu ZW, Wang ZG, Zhang Y, Tian SR, Wu JM, Zhu GC, Liang WT Tags: Ann Otol Rhinol Laryngol Source Type: research

Gastroesophageal Reflux during Enteral Feeding in Stroke Patients: A 24-hour Esophageal pH-monitoring Study
Conclusions: GER is associated with aspiration pneumonia and occurs more often in patients with stroke lesions in the left hemisphere.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2011 Category: Neurology Authors: Yukie Satou, Hiroaki Oguro, Yo Murakami, Keiichi Onoda, Shingo Mitaki, Chizuko Hamada, Ryo Mizuhara, Shuhei Yamaguchi Tags: Original Articles Source Type: research