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The heart in m.3243A > G carriers.
CONCLUSIONS: Cardiac involvement in m.3243A>G carriers has been only rarely systematically studied, which is perhaps why the incidence of cardiac diseases in MELAS is lower than would be expected. Myocardial abnormalities are much more frequent than arrhythmias or conduction defects. All symptomatic and asymptomatic m.3243A>G carriers should be systematically investigated for cardiac disease. PMID: 30128910 [PubMed - as supplied by publisher]
Source: Herz - August 23, 2018 Category: Cardiology Tags: Herz Source Type: research

Is there a role for tissue Doppler imaging in predicting thromboembolic risk? A challenging case report of dilated cardiomyopathy with intracardiac thrombus and recurrent stroke
No abstract available
Source: Journal of Cardiovascular Medicine - July 31, 2018 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

The contribution of systematic implementation of cardiovascular explorations for the detection of cardiac sources of embolism in patients with stroke: About 230  patients.
CONCLUSION: Cardiovascular explorations remain indispensable in the workup of all ischemic strokes even if their therapeutic effect is modest. The lacunar infarct out first at 34% followed by 32% of cardio embolic causes and atheroma of the neck vessels in approximately 16%. PMID: 29753425 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - May 9, 2018 Category: Cardiology Authors: Hadi A, Bendriss L, Khatouri A Tags: Ann Cardiol Angeiol (Paris) Source Type: research

Super High Dose Beta-blocker Administration for the Patients with Dilated Cardiomyopathy
First case is a 25-year-old female with dilated cardiomyopathy. Left ventricular end-diastolic diameter (LVEDD) was 74  mm and ejection fraction (EF) was 29%. Carvedilol was already uptitrated to 20 mg twice daily. Right heart catheterization (RHC) revealed very low cardiac output (C.O. 2.82 l/min), cardiac index (C.I. 1.47 l/min/m2), stroke volume (SV 29 ml) and rapid heart rate (HR 96/min) despite maximu m dosage of carvedilol in Japan. Carvedilol was uptitrated to 50 mg twice daily and additional 10 mg bisoprolol twice daily was started under administration of low-dose dobutamine.
Source: Journal of Cardiac Failure - September 20, 2017 Category: Cardiology Authors: Akihiro Isotani, Takashi Morinaga, Shintaro Mori, Shinya Ito, Makoto Hyodo, Shinichi Shirai, Kenji Ando Source Type: research

Key Questions Relating to Left Ventricular Noncompaction Cardiomyopathy: Is the Emperor Still Wearing Any Clothes?
Publication date: June 2017 Source:Canadian Journal of Cardiology, Volume 33, Issue 6 Author(s): Robert H. Anderson, Bjarke Jensen, Timothy J. Mohun, Steffen E. Petersen, Nay Aung, Filip Zemrak, R. Nils Planken, David H. MacIver The evidence is increasing that left ventricular noncompaction cardiomyopathy as it is currently defined does not represent a failure of compaction of pre-existing trabecular myocardium found during embryonic development to form the compact component of the ventricular walls. Neither is there evidence of which we are aware to favour the notion that the entity is a return to a phenotype seen in col...
Source: Canadian Journal of Cardiology - May 24, 2017 Category: Cardiology Source Type: research

Thirty years of heart transplantation at the University Medical Centre Utrecht.
CONCLUSION: Over the past 30 years, patient and donor demographics and underlying diseases have shifted substantially. Furthermore, the increase in waiting time due to lack of available donor hearts has led to a rise in the use of LVADs as bridge to transplant. Importantly, an improvement in survival rates is found over time which could be explained by better immunosuppressive therapy and improvements in follow-up care. PMID: 28247245 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - February 27, 2017 Category: Cardiology Authors: Sammani A, Wind AM, Kirkels JH, Klöpping C, Buijsrogge MP, Ramjakhan FZ, Asselbergs FW, de Jonge N Tags: Neth Heart J Source Type: research

Key Questions relating to left ventricular noncompaction cardiomyopathy - Is the Emperor still wearing any clothes?
Publication date: Available online 1 February 2017 Source:Canadian Journal of Cardiology Author(s): Robert H. Anderson, Bjarke Jensen, Timothy J. Mohun, Steffen E. Petersen, Nay Aung, Filip Zemrak, R Nils Planken, David H. MacIver The evidence is increasing that left ventricular noncompaction cardiomyopathy, as it is currently defined, does not represent failure of compaction of pre-existing trabecular myocardium found during embryonic development so as to form the compact component of the ventricular walls. Nor is there evidence, of which we are aware, to favour the notion that the entity is a return to a phenotype as se...
Source: Canadian Journal of Cardiology - January 31, 2017 Category: Cardiology Source Type: research

The Effects of Levosimendan and Sodium Nitroprusside Combination on Left Ventricular Functions After Surgical Ventricular Reconstruction in Coronary Artery Bypass Grafting Patients.
CONCLUSION: This study showed that LS and SNP combination impressive increase in left ventricular systolic and diastolic functions including LVEF. The use of this combination achieved more less inotrophics and IABP requirement. We therefore suggest preoperative and peroperative levosimendan and SNP combination. PMID: 27583039 [PubMed]
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research

Impact of papillary muscles on ventricular function measurements in 3T cardiac magnetic resonance
Conclusion Global CMR LV parameters are significantly affected by whether TPM are considered as part of the LV blood pool or as part of LV mass. Therefore, a consistent method of LV cavity delineation may be crucial during longitudinal follow-up to avoid misinterpretation and erroneous clinical decision-making.
Source: Cor et Vasa - September 1, 2016 Category: Cardiology Source Type: research

Patients Selection for Left Ventriculoplasty and Mitral Valve Surgery in Non-Ischemic Dilated Cardiomyopathy
The operative indication for dilated cardiomyopathy (DCM) is controversial. Subjects were 20 non-ischemic DCM patients. Left ventriculoplasty and mitral valve repair were conducted. Cardiac index derived from forward stroke volume significantly increased after surgery (from 1.8  ± 0.6 to 2.4 ± 0.6, P = .001). One-year survival rate was 58%. Slope in preload recruitable stroke work relationship (Mw) was an independent predictor for survival after surgery (HR, 0.936; 95%CI, 0.894–0.980; P = .005). Cut-off value of Mw for one-year survival was 42.
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Yasushige Shingu, Tomonori Ooka, Tsuyoshi Tachibana, Yoshiro Matsui Source Type: research

Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter‐Defibrillators Over Time in Ischemic and Dilated Cardiomyopathy Patients
Conclusions: These changes in clinical practice with a shift to primary prevention and rise in non‐ischemic cardiomyopathy implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real life cohort.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - May 15, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, STICHERLING CHRISTIAN, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: Original Source Type: research

Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain
Conclusion In patients with severe secondary MR, speckle-tracking GLS shows more deteriorated LV systolic function than LVEF.
Source: European Heart Journal - March 7, 2016 Category: Cardiology Authors: Kamperidis, V., Marsan, N. A., Delgado, V., Bax, J. J. Tags: Valvular heart disease Source Type: research

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