Filtered By:
Specialty: Cardiology
Condition: Dilated Cardiomyopathy

This page shows you your search results in order of relevance. This is page number 2.

Order by Relevance | Date

Total 88 results found since Jan 2013.

Anticoagulation in Patients with Dilated Cardiomyopathy, Low Ejection Fraction, and Sinus Rhythm: Back to the Drawing Board
Summary Heart failure patients present an important thrombo‐embolic risk, including symptomatic or silent peripheral arterial embolism, pulmonary embolism, and stroke. Patients in sinus rhythm who have concomitant depressed (<35%) left ventricular ejection fraction have a 4% rate of embolic events. Several prospective randomized trials of anticoagulation in this group of patients were either underpowered or had a short period of follow‐up. Even though in two studies warfarin had a slight advantage over aspirin (in the WATCH and WARCEF trials), it was at the cost of an increased risk in major hemorrhage. To decrease ...
Source: Cardiovascular Therapeutics - September 12, 2013 Category: Cardiology Authors: Alexandru Nicolae Mischie, Valentin Chioncel, Ionel Droc, Crina Sinescu Tags: Short communication Source Type: research

Cardiac MRI assessment of atrial fibrosis in atrial fibrillation: implications for diagnosis and therapy
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia in clinical practice, with a prevalence of 0.4–1% in the US population.w1 AF is a potent risk factor, increasing the risk of stroke fivefold and accounting for approximately 15% of all strokes in the USA.w2 AF also significantly increases the risk of mortality from heart failure.w3–7 Many therapies, including pharmacological approaches and direct current cardioversion, have been tried to treat this malignant arrhythmia, but were not found to be that effective.1 w8–w11 Catheter ablation of AF has provided better outcomes compared ...
Source: Heart - March 5, 2014 Category: Cardiology Authors: Higuchi, K., Akkaya, M., Akoum, N., Marrouche, N. F. Tags: Tachyarrhythmias, Atrial fibrillation, Education in Heart, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Heart failure, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Source Type: research

Atorvastatin improves systolic function, but does not prevent the development of dilated cardiomyopathy in streptozotocin-induced diabetic rats
Conclusions: Whereas atorvastatin does not reverse ventricular dilatation, it does have a positive hemodynamic effect on the CV system of diabetic rats. This hemodynamic benefit is independent of cholesterol levels, and is observed concomitantly with reduced oxidative stress, vascular remodeling, and improved endothelial function. Together, these results suggest that atorvastatin decreases the workload on the heart and improves systolic performance in type 1 diabetic rats by reducing oxidative stress, vascular tone, and systemic vascular resistance.
Source: Therapeutic Advances in Cardiovascular Disease - June 11, 2014 Category: Cardiology Authors: Quidgley, J., Cruz, N., Crespo, M. J. Tags: Original Research Source Type: research

Adipose tissue-derived stem cells as a therapeutic tool for cardiovascular disease.
Abstract Adipose tissue-derived stem cells (ADSCs) are adult stem cells that can be easily harvested from subcutaneous adipose tissue. Many studies have demonstrated that ADSCs differentiate into vascular endothelial cells (VECs), vascular smooth muscle cells (VSMCs), and cardiomyocytes in vitro and in vivo. However, ADSCs may fuse with tissue-resident cells and obtain the corresponding characteristics of those cells. If fusion occurs, ADSCs may express markers of VECs, VSMCs, and cardiomyocytes without direct differentiation into these cell types. ADSCs also produce a variety of paracrine factors such as vascular...
Source: World Journal of Cardiology - August 26, 2015 Category: Cardiology Authors: Suzuki E, Fujita D, Takahashi M, Oba S, Nishimatsu H Tags: World J Cardiol Source Type: research

Major depressive disorder in chronic heart failure patients: Does silent cerebral infarction cause major depressive disorder in this patient population?
CONCLUSION: CHF patients have an increased prevalence of SCI and MDD. Patients with SCI have a higher prevalence of MDD compared to patients without SCI in CHF. PMID: 26363742 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - September 1, 2015 Category: Cardiology Authors: Kozdağ G, Yaluğ İ, İnan N, Ertaş G, Selekler M, Kutlu H, Kutlu A, Emre E, Çetin M, Ural D Tags: Turk Kardiyol Dern Ars Source Type: research

Stoke Work Index Predicts Left Ventricular Reverse Remodeling
To examine whether left ventricular stroke work index (LVSWI) predicts LV reverse remodeling after surgery for patients with ischemic dilated cardiomyopathy.
Source: Journal of Cardiac Failure - September 25, 2015 Category: Cardiology Authors: Yasushige Shingu, Satoru Wakasa, Tomonori Ooka, Tsuyoshi Tachibana, Yoshiro Matsui Source Type: research

MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis
Abstract Heart failure remains an important clinical burden, and mitochondrial dysfunction plays a key role in its pathogenesis. The heart has a high metabolic demand, and mitochondrial function is a key determinant of myocardial performance. In mitochondrial disorders, hypertrophic remodeling is the early pattern of cardiomyopathy with progression to dilated cardiomyopathy, conduction defects and ventricular pre-excitation occurring in a significant proportion of patients. Cardiac dysfunction occurs in approximately a third of patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like e...
Source: Heart Failure Reviews - December 28, 2015 Category: Cardiology Source Type: research

Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain
Conclusion In patients with severe secondary MR, speckle-tracking GLS shows more deteriorated LV systolic function than LVEF.
Source: European Heart Journal - March 7, 2016 Category: Cardiology Authors: Kamperidis, V., Marsan, N. A., Delgado, V., Bax, J. J. Tags: Valvular heart disease Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter‐Defibrillators Over Time in Ischemic and Dilated Cardiomyopathy Patients
Conclusions: These changes in clinical practice with a shift to primary prevention and rise in non‐ischemic cardiomyopathy implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real life cohort.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - May 15, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, STICHERLING CHRISTIAN, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: Original Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research

Impact of papillary muscles on ventricular function measurements in 3T cardiac magnetic resonance
Conclusion Global CMR LV parameters are significantly affected by whether TPM are considered as part of the LV blood pool or as part of LV mass. Therefore, a consistent method of LV cavity delineation may be crucial during longitudinal follow-up to avoid misinterpretation and erroneous clinical decision-making.
Source: Cor et Vasa - September 1, 2016 Category: Cardiology Source Type: research

Key Questions relating to left ventricular noncompaction cardiomyopathy - Is the Emperor still wearing any clothes?
Publication date: Available online 1 February 2017 Source:Canadian Journal of Cardiology Author(s): Robert H. Anderson, Bjarke Jensen, Timothy J. Mohun, Steffen E. Petersen, Nay Aung, Filip Zemrak, R Nils Planken, David H. MacIver The evidence is increasing that left ventricular noncompaction cardiomyopathy, as it is currently defined, does not represent failure of compaction of pre-existing trabecular myocardium found during embryonic development so as to form the compact component of the ventricular walls. Nor is there evidence, of which we are aware, to favour the notion that the entity is a return to a phenotype as se...
Source: Canadian Journal of Cardiology - January 31, 2017 Category: Cardiology Source Type: research

Thirty years of heart transplantation at the University Medical Centre Utrecht.
CONCLUSION: Over the past 30 years, patient and donor demographics and underlying diseases have shifted substantially. Furthermore, the increase in waiting time due to lack of available donor hearts has led to a rise in the use of LVADs as bridge to transplant. Importantly, an improvement in survival rates is found over time which could be explained by better immunosuppressive therapy and improvements in follow-up care. PMID: 28247245 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - February 27, 2017 Category: Cardiology Authors: Sammani A, Wind AM, Kirkels JH, Klöpping C, Buijsrogge MP, Ramjakhan FZ, Asselbergs FW, de Jonge N Tags: Neth Heart J Source Type: research