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Cancer: Prostate Cancer
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Total 1438 results found since Jan 2013.
Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research
Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer
Urologie. 2023 Sep 13. doi: 10.1007/s00120-023-02189-z. Online ahead of print.ABSTRACTProstate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-...
Source: Nuklearmedizin - September 13, 2023 Category: Radiology Authors: Anna-Sophie Strau ß Christian Bolenz Ambros J Beer Friedemann Zengerling Meinrad Beer Jonathan Miksch Source Type: research
Cancers, Vol. 15, Pages 4404: PET/CT and Conventional Imaging for the Assessment of Neuroendocrine Prostate Cancer: A Systematic Review
Conclusion: Published data on the role of PET/CT for the assessment of NEPC are limited. At present, it is still uncertain which tracer performs best, and although [18F]FDG has been evaluated and seems to offer some advantages in availability and clinical staging, other tracers may be more useful to understand tumor biology or identify targets for subsequent radioligand therapy. Further research is therefore desirable. In contrast, data are still limited to draw a final conclusion on the role and the specific characteristics of CI in this rare form of neoplasm, and therefore, more studies are needed in this setting.
Source: Cancers - September 3, 2023 Category: Cancer & Oncology Authors: Francesco Dondi Alessandro Antonelli Nazareno Suardi Andrea Emanuele Guerini Domenico Albano Silvia Lucchini Luca Camoni Giorgio Treglia Francesco Bertagna Tags: Review Source Type: research
PSMA PET/CT and PET/MRI in primary staging of prostate cancer and its effect on patient management
ConclusionsDespite the clear superiority of PSMA PET over conventional imaging for primary staging of intermediate- and high-risk PCa, PSMA PET is currently not yet identified as the gold standard imaging modality in this setting in the European Association of Urology (EAU) guidelines, given that no prospective studies demonstrating a clear benefit of treatment adaptation are available at this moment. The results of prospective trials exploring the benefit of PSMA PET-based treatment algorithms are, therefore, strongly awaited.
Source: Clinical and Translational Imaging - August 30, 2023 Category: Radiology Source Type: research
The Balance Between the Therapeutic Efficacy and Safety of < sup > 177 < /sup > LuLu-NeoB in a Preclinical Prostate Cancer Model
CONCLUSIONS: Treatment with [177Lu]Lu-NeoB is effective in a preclinical PCa model. Adjusting the administered dose could positively impact the risk-benefit balance as a higher dose might not lead to an increased therapeutic effect, but it may lead to an increase in toxicological effects in healthy organs such as the kidneys.PMID:37640941 | DOI:10.1007/s11307-023-01851-4
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Marjolein Verhoeven Joost Haeck Erik de Blois Francesca Orlandi Donato Barbato Mattia Tedesco Mark Konijnenberg Simone U Dalm Source Type: research
Prostate-specific membrane antigen-based imaging for stereotactic irradiation of low-volume progressive prostate cancer: a single-center experience
CONCLUSION: PSMA-based imaging is a promising diagnostic method for specifying the stage and detecting the low-volume progression. Our results suggest that PSMA-based hybrid imaging can influence treatment decisions and target volume delineation for SBRT.PMID:37637070 | PMC:PMC10448522 | DOI:10.3389/fonc.2023.1166665
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Linda Varga Zsuzsanna Besenyi Viktor R Paczona Istv án Farkas Szabolcs Urb án G ábor Sipka L ászló Pávics Zoltan Varga Emese Fodor Katalin Hidegh éty Judit Olah Zolt án Bajory Anik ó Maráz Source Type: research
A randomised trial of < sup > 18 < /sup > FPSMA-1007-PET/CT versus NaF-PET/CT for staging primary prostate cancer: A trial protocol
BJUI Compass. 2023 May 12;4(5):513-522. doi: 10.1002/bco2.243. eCollection 2023 Sep.ABSTRACTBACKGROUND: Prostate-specific membrane antigen (PSMA)-positron emission tomography/contrast-enhanced computed tomography (PET/CT) is a sensitive imaging modality for prostate cancer (PCa). Due to lack of knowledge of the patient benefit, PSMA-PET/CT is not yet recommended in the European guidelines for staging and treatment planning of patients with newly diagnosed PCa. We will investigate the potential difference in progression-free survival (PFS) and quality of life (QoL) of using PSMA-PET/CT versus sodium fluoride (NaF)-PET/CT fo...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Karen Middelbo Buch-Olsen Mads Hvid Poulsen Steinbj ørn Hansen Mie Holm Vilstrup Jorun Holm S øren Hess Paw Christian Holdgaard Karsten Egbert Arnold Zieger S øren Sørensen Madsen Oke Gerke Kasper Tholstrup Pedersen Johan Hygum Dam Niels Langkj ær Lo Source Type: research
Efficient segmentation using domain adaptation for MRI-guided and CBCT-guided online adaptive radiotherapy
CONCLUSION: The proposed method utilizing personalized modeling improved the segmentation accuracy of ART.PMID:37634767 | DOI:10.1016/j.radonc.2023.109871
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 27, 2023 Category: Radiology Authors: Yuxiang Liu Bining Yang Xinyuan Chen Ji Zhu Guangqian Ji Yueping Liu Bo Chen Ningning Lu Junlin Yi Shulian Wang Yexiong Li Jianrong Dai Kuo Men Source Type: research
A comparison of the sarcopenic effect of androgen receptor-axis-targeted agents vs. androgen deprivation alone in patients with metastatic prostate cancer
CONCLUSIONS: Although we found no significant difference in the sarcopenic effects of GnRH alone, GnRH with abiraterone, or GnRH with enzalutamide in our cohort of 55 hormone-naive metastatic prostate cancer patients, overall decreases in muscle mass were observed for all three groups. This highlights the importance of muscle-retaining strategies for patients undergoing ADT for metastatic prostate cancer, regardless of therapeutic regimen.PMID:37581552 | DOI:10.5489/cuaj.8245
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Tarek Lawen Kaveh Masoumi-Ravandi Ricardo A Rendon Liette Connor Ross J Mason Source Type: research
