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Total 532 results found since Jan 2013.

Midlife fitness predicts less burden of chronic disease in later life.
CONCLUSIONS: Healthy, fit, middle-aged adults developed fewer chronic conditions in later life than unfit persons and had a lesser burden of chronic disease before death. PMID: 24169299 [PubMed - in process]
Source: Clinical Lung Cancer - November 1, 2013 Category: Cancer & Oncology Authors: Rantanen T Tags: Clin J Sport Med Source Type: research

Isolated Shoulder Palsy due to Cortical Infarction: A Case Report and Literature Review of Clinicoradiological Correlations
We report an 80-year-old woman with isolated shoulder palsy because of cortical ischemic infarction in the base of the left precentral gyrus as confirmed by brain magnetic resonance imaging. In our patient, cardiogenic embolism or Trousseau syndrome associated with lung cancer was considered the cause of ischemic infarction. Physicians should consider small cortical infarction, when a patient complains of sudden onset of shoulder weakness without pain. In line with the previous reports, a responsible cortical lesion in our patient corresponded to motor shoulder area in the motor homunculus reported to be located more media...
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2013 Category: Neurology Authors: Akiko Kawasaki, Keisuke Suzuki, Hidehiro Takekawa, Norito Kokubun, Masanari Yamamoto, Yohei Asakawa, Madoka Okamura, Koichi Hirata Tags: Case Reports Source Type: research

Sudden cardiac death: a critical appraisal of the implantable cardioverter defibrillator
Summary ImportanceApproximately 350,000 Americans still die of sudden cardiac death each year. This exceeds the number of patients who die annually from stroke, lung cancer, breast cancer and AIDS combined. ObjectiveThis review aims to trace the history of implantable cardioverter defibrillators (ICD) with reference to landmark trials and their influence on the formulation of Medicare guidelines for ICD implantation criteria. This paper will also discuss the cost‐effectiveness of ICDs and the quality of life after implantation. The reasons for the disparity between guidelines for implantation and actual clinical practice...
Source: International Journal of Clinical Practice - December 22, 2013 Category: Internal Medicine Authors: A. Rajabali, E. K. Heist Tags: Review Article Source Type: research

Estimating the decline in excess risk of chronic obstructive pulmonary disease following quitting smoking - a systematic review based on the negative exponential model.
Abstract We quantified the decline in COPD risk following quitting using the negative exponential model, as previously carried out for other smoking-related diseases. We identified 14 blocks of RRs (from 11 studies) comparing current smokers, former smokers (by time quit) and never smokers, some studies providing sex-specific blocks. Corresponding pseudo-numbers of cases and controls/at risk formed the data for model-fitting. We estimated the half-life (H, time since quit when the excess risk becomes half that for a continuing smoker) for each block, except for one where no decline with quitting was evident, and H...
Source: Regulatory Toxicology and Pharmacology : RTP - December 19, 2013 Category: Toxicology Authors: Lee PN, Fry JS, Forey B Tags: Regul Toxicol Pharmacol Source Type: research

Widening Rural–Urban Disparities in Life Expectancy, U.S., 1969–2009
Conclusions: Between 1969 and 2009, residents in metropolitan areas experienced larger gains in life expectancy than those in nonmetropolitan areas, contributing to the widening gap.
Source: American Journal of Preventive Medicine - January 17, 2014 Category: Global & Universal Authors: Gopal K. Singh, Mohammad Siahpush Tags: Research Articles Source Type: research

Early ambulatory palliative care visits focus on psychosocial elements such as building rapport and coping, as well as managing symptoms and enhancing illness understanding
This study has had significant impact, but many professionals have asked for more details about palliative care interventions. Findings from the present study will help define what palliative care specifically provides. Context Professional organisations in the fields of oncology, such as the American Society of Clinical Oncology2 and palliative care, including the American Academy of Hospice and Palliative Medicine, have articulated the need for palliative care to be integrated into disease-focused care. There has been a wide international interest in this area as well. Achieving this aim will require a greater understanding...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Ferrell, B. Tags: End of life decisions (geriatric medicine), Adult nursing, Stroke, Lung cancer (oncology), End of life decisions (palliative care), Hospice, Lung cancer (respiratory medicine), End of life decisions (ethics), Resuscitation, Information management Source Type: research

ONS suggests that one in four deaths are 'avoidable'
“1 in 4 deaths could have been prevented,” The Times reports. Figures released by the Office for National Statistics (ONS) found that 23% of deaths could have been prevented through better care, more effective treatment and healthier living. The news is based on an ONS bulletin titled Avoidable Mortality in England and Wales, 2012 (PDF 186kb). The bulletin provides mortality figures for causes of death that are considered avoidable if timely and effective healthcare is received or healthier lifestyle choices adopted. Figures were provided for the period 2001 to 2012 so that trends can be seen. The bulletin found tha...
Source: NHS News Feed - May 8, 2014 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Cancer QA articles Source Type: news

P-119 * different measures to prevent atrial fibrillation in patients undergoing pulmonary resection for lung cancer: evidence from a comprehensive network meta-analysis of randomized and observational studies
Conclusions: Beta-blockers and flecainide are effective in reducing the incidence of postoperative AF in patients after pulmonary resections which is not the case with digoxin; data on remaining treatments are sparse and preclude drawing definite conclusions. Disclosure: No significant relationships.
Source: Interactive CardioVascular and Thoracic Surgery - June 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kowalewski, M., Lewandowska, M. A., Kowalewski, J. Tags: SESSION VII: MODERATED POSTERS Source Type: research

P-154 * bilobectomy for non-small-cell lung cancer: results of a multicentre study on 425 cases
Conclusions: Bilobectomy is associated with increased morbidity. Five-year survival is influenced by tumour stage and completeness of resection. Worse survival occurs in adenocarcinoma and bronchus intermedius involvement. Disclosure: No significant relationships.
Source: Interactive CardioVascular and Thoracic Surgery - June 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Filosso, P. L., Welter, S., Rena, O., Ampollini, L., Siedlecka, D., Avaro, J. P., Anile, M., Margaritora, S., Pischik, V., Thomas, P. Tags: SESSION VII: MODERATED POSTERS Source Type: research

Perspectives on end of life care
It looked at three conditions, heart failure, lung cancer and stroke, chosen to represent differing disease trajectories. More ....
Source: NHS Networks - June 19, 2014 Category: UK Health Authors: Maria Axford Source Type: news

Preemie baby and toothless adults urge smokers to quit in new CDC ads
You probably know that smoking causes lung cancer, emphysema and heart disease. But former smokers want you to know that cigarettes can give you a stroke, make your teeth fall out and cause your baby to be born dangerously early.
Source: Los Angeles Times - Science - June 25, 2014 Category: Science Source Type: news

Lung cancer screening with low-dose CT (LDCT) is ready for prime time in the USA
Commentary on: Humphrey LL, Deffebach M, Pappas M, et al.. Screening for lung cancer with low-dose computed tomography: a systematic review to update the US Preventive Services Task Force recommendation. Ann Intern Med 2013;159:411–20. Context The US Preventative Services Task Force (USPSTF) has published their long-awaited, updated systematic review of low-dose CT (LDCT) screening for lung cancer. Last reviewed in 2004, lung cancer screening has been under intense study worldwide for the past decade. The issue of lung cancer screening is important because lung cancer is the leading cause of cancer mortality in the U...
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Wilson, D. O. Tags: Smoking and tobacco, Health policy, Clinical trials (epidemiology), Epidemiologic studies, Immunology (including allergy), Stroke, Screening (oncology), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Health econom Source Type: research

Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches.
Abstract It has been clear that at least 1 billion adults worldwide are smokers and at least 700 million children are passive smokers at home. Smoking exerts a detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease, cancer of head and neck, cancer of the urinary and gastrointestinal tract, periodontal disease, cataract and arthritis. Additionally, smoking is an important modifiable risk factor for the development of cardiovascular disease such as coronary artery disease, stable angina, acute coronary syndromes, sudden death, s...
Source: Current Medicinal Chemistry - August 26, 2014 Category: Chemistry Authors: Siasos G, Tousoulis D, Michalea S, Oikonomou E, Vavuranakis M, Athanasiou D, Tourikis P, Gouliopoulos N, Miliou A, Mazaris S, Papavassiliou AG, Stefanadis C Tags: Curr Med Chem Source Type: research

Bm-19 * symptomatic and economic burden of brain metastases in patients with alk+ nsclc
CONCLUSIONS: BM presents a substantial symptomatic and economic burden in patients with ALK+ NSCLC. Given the large percentage of ALK+ NSCLC patients who will eventually develop BM, this highlights an important unmet need.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Macalalad, A., Sasane, M., Zhang, J., Culver, K., Dea, K., Nitulescu, R., Wu, E., Guerin, A. Tags: BRAIN METASTASES (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

Cause-specific mortality by education in Canada: a 16-year follow-up study.
This study examines cause-specific mortality rates by education in a broadly representative sample of Canadians aged 25 or older. The data are from the 1991 to 2006 Canadian census mortality follow-up study, which included about 2.7 million people and 426,979 deaths. Age-standardized mortality rates (ASMRs) were calculated by education for different causes of death. Rate ratios, rate differences and excess mortality were also calculated. RESULTS: All-cause ASMRs were highest among people with less than secondary graduation and lowest for university degree-holders. If all cohort members had the mortality rates of those ...
Source: Health Reports - November 14, 2014 Category: Global & Universal Tags: Health Rep Source Type: research