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PET/CT features of lung SABR chest wall toxicity
SummaryStereotactic ablative radiotherapy offers a radical treatment approach for early stage lung cancers and an aggressive local therapy for pulmonary oligometastases from other tumour sites. Chest wall toxicity is one of the key dose ‐limiting toxicities for intrathoracic stereotactic treatments. The description of stereotactic radiotherapy chest wall toxicity using functional imaging has not been reported previously. A 56‐year‐old male received 60 Gy in 8 fractions delivered by volumetric modulated arc therapy for a T1bN0 M0 clinical left upper lobe lung cancer. The past medical history included poorly controlled...
Source: Journal of Medical Imaging and Radiation Oncology - February 7, 2021 Category: Radiology Authors: Urvashi Singh,
Gerard M Walls,
Gerard G Hanna,
Tom B Lynch,
Jonathan McAleese Tags: Medical Imaging —Radiation Oncology—Case Letter Source Type: research
ESMO 2019 —personal non-small lung cancer highlights
In conclusion, ESMO 2019 fueled the lung cancer c ommunity with inspiring new data, contributing to a more individualized, hopefully improved lung cancer treatment and continuing to decrease lung cancer mortality.
Source: Memo - Magazine of European Medical Oncology - March 19, 2020 Category: Cancer & Oncology Source Type: research
Cannabis-based medicines and medical cannabis for adults with cancer pain
CONCLUSIONS: There is moderate-certainty evidence that oromucosal nabiximols and THC are ineffective in relieving moderate-to-severe opioid-refractory cancer pain. There is low-certainty evidence that nabilone is ineffective in reducing pain associated with (radio-) chemotherapy in people with head and neck cancer and non-small cell lung cancer. There is low-certainty evidence that a single dose of synthetic THC analogues is not superior to a single low-dose morphine equivalent in reducing moderate-to-severe cancer pain. There is low-certainty evidence that CBD does not add value to specialist palliative care alone in the ...
Source: Cochrane Database of Systematic Reviews - June 7, 2023 Category: General Medicine Authors: Winfried H äuser Patrick Welsch Lukas Radbruch Emma Fisher Rae Frances Bell R Andrew Moore Source Type: research
Basket Trials for Intractable Cancer
This study has made a significant impact on clinical practice in cancer patients harboring the TRK translocation, and also illustrates the potential for future advancements in drug development and clinical trials of cancers harboring rare genomic alterations (50).
Second, a basket trial may allow screening for potential efficacy across multiple tumor types in order to guide more traditional, disease-specific, follow-up studies. The goal of some basket trials is to obtain an overall assessment of the drug with pooled histologies; in such trials, subsequent analyses are straightforward, and are comparable to those in standa...
Source: Frontiers in Oncology - April 11, 2019 Category: Cancer & Oncology Source Type: research
Cannabis-based medicines and medical cannabis for adults with cancer pain
CONCLUSIONS: There is moderate-certainty evidence that oromucosal nabiximols and THC are ineffective in relieving moderate-to-severe opioid-refractory cancer pain. There is low-certainty evidence that nabilone is ineffective in reducing pain associated with (radio-) chemotherapy in people with head and neck cancer and non-small cell lung cancer. There is low-certainty evidence that a single dose of synthetic THC analogues is not superior to a single low-dose morphine equivalent in reducing moderate-to-severe cancer pain. There is low-certainty evidence that CBD does not add value to specialist palliative care alone in the ...
Source: Cochrane Database of Systematic Reviews - June 7, 2023 Category: General Medicine Authors: Winfried H äuser Patrick Welsch Lukas Radbruch Emma Fisher Rae Frances Bell R Andrew Moore Source Type: research
Association Between Cancer Incidence and Mortality in Web-Based Data in China: Infodemiology Study
Conclusions: Search behaviors indeed reflect public awareness of cancer from a different angle. Research on internet search behaviors could present an innovative and timely way to monitor and estimate cancer incidence and mortality rates, especially for cancers not included in national registries.
Source: Journal of Medical Internet Research - January 29, 2019 Category: General Medicine Authors: Chenjie Xu Yi Wang Hongxi Yang Jie Hou Li Sun Xinyu Zhang Xinxi Cao Yabing Hou Lan Wang Qiliang Cai Yaogang Wang Source Type: research
The Limits of Google: How Patients Can Find Out What Works In Medical Care
This report increased the likelihood that patients who might benefit from the drug will have it covered by their insurance.
ICER calculates a fair benchmark price to the manufacturer, the payer, the patient and the overall health system, so that these decisions can be made collaboratively in full view of you, the patient. These decisions have always been made behind closed doors, so the fact that cost is being addressed and discussed openly provides patients with a significant advantage.
Still, when it comes to considering costs, some patient advocacy groups get nervous when the subject comes up. I would not be fair if I...
Source: Science - The Huffington Post - July 27, 2016 Category: Science Source Type: news
NSCLC and Melanoma Lead Continuing Fall in US Cancer Death Rates NSCLC and Melanoma Lead Continuing Fall in US Cancer Death Rates
Cancer death rates in the US continue to decline overall for many common cancers in both men and women, especially non –small cell lung cancer (NSCLC) and melanoma.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - July 14, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies
J Med Libr Assoc. 2022 Apr 1;110(2):185-204. doi: 10.5195/jmla.2022.1306.ABSTRACTINTRODUCTION: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines. We aimed to develop and validate an objectively derived content search strategy containing generic search terms that can be adapted for any search for evidence on patient-based BRA of medicines for any therapeutic area.METHODS: We used a robust multistep process to develop and validate the content search strategy: (1) we developed a bank of search terms derived from s...
Source: J Med Libr Assoc AND... - April 20, 2022 Category: Databases & Libraries Authors: Hiba El Masri Treasure M McGuire Christine Dalais Mieke van Driel Helen Benham Samantha A Hollingworth Source Type: research
