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Total 18961 results found since Jan 2013.

Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium
CONCLUSION: Our data suggest that breastfeeding does not protect against CBT.PMID:37421504 | DOI:10.1007/s10552-023-01746-3
Source: Cancer Control - July 8, 2023 Category: Cancer & Oncology Authors: Jeremy M Schraw Eleni Th Petridou Audrey Bonaventure John D Dockerty Maria Karalexi Evangelia Ntzani Claire Infante-Rivard Jacqueline Clavel Paige M Bracci Roberta McKean-Cowdin Eve Roman Eleanor Kane Friederike Erdmann Joachim Sch üz Beth A Mueller Mich Source Type: research

Breastfeeding and Nutrition to 2 Years of Age and Risk of Childhood Acute Lymphoblastic Leukemia and Brain Tumors.
Abstract Acute lymphoblastic leukemia (ALL) and childhood brain tumors (CBT) are 2 of the most common forms of childhood cancer, but little is known of their etiology. In 2 nationwide case-control studies we investigated whether breastfeeding, age of food introduction, or early diet are associated with the risk of these cancers. Cases aged 0-14 years were identified from Australian pediatric oncology units between 2003 and 2007 (ALL) and 2005 and 2010 (CBT) and population-based controls through nationwide random-digit dialing. Mothers completed questionnaires giving details of infant feeding up to the age of 2 y...
Source: Nutrition and Cancer - February 3, 2015 Category: Cancer & Oncology Authors: Greenop KR, Bailey HD, Miller M, Scott RJ, Attia J, Ashton LJ, Downie P, Armstrong BK, Milne E Tags: Nutr Cancer Source Type: research

Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium
ConclusionOur data suggest that breastfeeding does not protect against CBT.
Source: Cancer Causes and Control - July 8, 2023 Category: Cancer & Oncology Source Type: research

Characterizing internet search patterns for neurologic and neurosurgical conditions following celebrity diagnosis
CONCLUSIONS: Following major events related to the neurological disease of public figures there is an expected rise in Google search interest relevant to these topics. Our findings suggest that there is an optimal window of approximately 2 weeks following each of these events for activist and clinical groups to publicize their desired message, and for the field of neurosurgery and neurological science to increase public awareness regarding specific diseases, with a regression to baseline interest by 4-months following the event.PMID:34763394 | DOI:10.23736/S0390-5616.21.05569-7
Source: Journal of Neurosurgical Sciences - November 12, 2021 Category: Neurosurgery Authors: Max S Ward Michael J Feldman Brittany N Ward Vera Ong Nolan J Brown Shane Shahrestani Chen Y Yang Mickey E Abraham Boris Paskhover Anil Nanda Source Type: research

Cancers, Vol. 13, Pages 3028: Co-Deregulated miRNA Signatures in Childhood Central Nervous System Tumors: In Search for Common Tumor miRNA-Related Mechanics
Conclusions: Our approach could prove significant in the search for global miRNA targets for tumor diagnosis and therapy. To the best of our knowledge, there are no previous reports concerning the present approach.
Source: Cancers - June 17, 2021 Category: Cancer & Oncology Authors: George I. Lambrou Apostolos Zaravinos Maria Braoudaki Tags: Article Source Type: research

Do animal models of brain tumors replicate human peritumoral edema? a systematic literature search
ConclusionNo animal model currently exists that enable the investigation of novel candidates for the treatment of peritumoral brain edema. With current interest in alternative treatments for peritumoral brain edema, there is an unmet need for clinically relevant animal models.
Source: Journal of Neuro-Oncology - February 9, 2023 Category: Cancer & Oncology Source Type: research

Rare-43. search for druggable targets in primary nervous system melanotic tumors: melanocytomas, melanotic schwannomas, primary melanomas
Due to the extreme rarity of primary nervous system melanotic tumors, relatively limited studies have been conducted attempting to identify distinguishing mutations and/or druggable targets. Melanocytomas share GNAQ mutations with uveal melanoma (Brain Pathol. 25:202-8, 2015; Acta Neuropathol 119:317-323, 2010); clinical trials in uveal melanomas have shown that MEK inhibition may result in clinical benefit in tumors with these mutations. BRAF V600E mutations (paralleled by BRAF VE1 immunohistochemistry) are targetable by vemurafenib, but large numbers of primary nervous system melanomas have not been assessed. Adding to t...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Lillehei, K., Davies, K., Aisner, D., Kleinschmidt-DeMasters, B. K. Tags: RARE TUMORS Source Type: research