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Long-term incidence of haematological cancer after bariatric surgery or usual care in the Swedish Obese Subjects study: a prospective cohort study
This study is registered with ClinicalTrials.gov (NCT01479452) and is ongoing.FINDINGS: A total of 4047 individuals with obesity were enrolled between Sept 1, 1987, and Jan 31, 2001. Overall, 34 participants in the surgery group and 51 participants in the usual care control group were diagnosed with haematological cancer during follow-up (hazard ratio [HR] 0·60; 95% CI 0·39-0·92; p=0·020). Moreover, there were three deaths by haematological cancer in the surgery group and 13 deaths in the control group (0·22; 0·06-0·76; p=0·017). Surgery was also associated with a reduced incidence of lymphoma (0·45; 0·23-0·88; ...
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Kajsa Sj öholm Johanna C Andersson-Assarsson Felipe M Kristensson Stephan Hjorth Hege Gravdahl Garelius Peter Jacobson Per-Arne Svensson Sofie Ahlin Bj örn Carlsson Markku Peltonen Lena M S Carlsson Magdalena Taube Source Type: research

Unraveling crime scenes strand by strand: the forensic odyssey of Bruce Budowle
Biotechniques. 2023 Aug 25. doi: 10.2144/btn-2023-0069. Online ahead of print.ABSTRACTBruce Budowle speaks to Ashling Cannon, Journal Development Editor for BioTechniques, about advancements & challenges in forensic science. Budowle completed his doctorate in genetics at Virginia Tech (VA, USA) formally known as Virginia Polytechnic Institute and State University. He then went on to complete a postdoctoral fellowship at the University of Alabama at Birmingham (AL, USA) to study genetic risk factors for acute lymphocytic leukemia, diabetes and melanoma. Budowle was early in his career and hadn't spent much time in foren...
Source: BioTechniques - August 25, 2023 Category: Biotechnology Authors: Bruce Budowle Source Type: research

HTLV on the government agenda: the case of the states of Bahia and Minas Gerais, Brazil
This article aimed to investigate and analyze the process of inclusion of HTLV on the government agenda in the states of Bahia and Minas Gerais, and which impacted health sector actions and policies. Interviews were held with key actors, and a document search was performed for analysis, using as the main reference the Multiple Streams framework proposed by John Kingdon. Various factors contributed to the theme's inclusion on the health sector agenda in Bahia, the state of Brazil with the widest range of policies on HTLV, involving high prevalence of the infection, a favorable political context, and activism by infected ind...
Source: Cadernos de Saude Publica - December 8, 2021 Category: International Medicine & Public Health Authors: Ionara Ferreira da Silva Garcia Élida Azevedo Hennington Source Type: research

Fight Aging! Newsletter, November 22nd 2021
This study nicely illustrates the importance of the cellular metabolic state of myeloid cells: it highlights that not only the availability of glucose, but also its channeling into different pathways (glycolysis versus glycogen synthesis) contributes to maintaining proper myeloid function. On the Ability of Redundant Blood Vessels to Lower Cardiovascular Mortality https://www.fightaging.org/archives/2021/11/on-the-ability-of-redundant-blood-vessels-to-lower-cardiovascular-mortality/ A few strategies offer the possibility of growing additional redundant blood vessels, though this is far from rigorously pr...
Source: Fight Aging! - November 21, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Zeolites as Carriers of Antitumor Ribonuclease Binase
In this study we tested the clinoptilolite, chabazite, and natrolite ability to be loaded by antitumor ribonuclease binase and the cytotoxicity of the obtained complexes. We found the optimal conditions for binase loading into zeolites and established the dynamic of its release. Cytotoxic effects of zeolite-binase complexes toward colorectal cancer Caco2 cells were characterized after 24 and 48 h of incubation with cells using MTT-test. Zeolites were toxic by itselfs and reduced cells viability by 30% (clinoptilolite), 40% (chabazite), and 70% (natrolite) after 48 h of incubation. Binase complexes with clinoptilolite as we...
Source: Frontiers in Pharmacology - May 2, 2019 Category: Drugs & Pharmacology Source Type: research

Artificial Intelligence at RSNA: I ' m Sorry, Dave. I ' m Afraid I Won ' t Be Taking Over...
DISCUSSION all over RSNA was Artificial Intelligence, and in particular, AI as applied to Radiology. Well, let ' s be even more specific. There was a cloud (pun intended) hanging over McCormick, the specter of RSNA Yet To Come, which I quite presciently predicted in my 2011RSNA Christmas Carol:I sat down on a PET/CT gantry and bowed my head. The room spun, and when I looked up again, we were seated on a bench beside Lake Michigan. It was a blustery day, with winds one only sees in Chicago in the winter. Strangely, I felt no chill, as I watched leaves blowing through the PACSman ' s shadowy figure.I looked behind me and gas...
Source: Dalai's PACS Blog - December 11, 2016 Category: Radiology Source Type: blogs

What scientific idea is ready for retirement?
Each year a forum for the world's most brilliant minds asks one question. This year's drew responses from such names as Richard Dawkins, Ian McEwan and Alan Alda. Here, edge.org founder John Brockman explains how the question came into being and we pick some of the best responsesEdge.org was launched in 1996 as the online version of "the Reality Club", an informal gathering of intellectuals who met from 1981 to 1996 in Chinese restaurants, artist lofts, investment banking firms, ballrooms, museums, living rooms and elsewhere. Though the venue is now in cyberspace, the spirit of the Reality Club lives on in the lively back-...
Source: Guardian Unlimited Science - January 12, 2014 Category: Science Authors: The Observer Tags: Astronomy Biology Mathematics Technology Physics Features Internet Animal behaviour The Observer Science Source Type: news