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Cancer: Breast Cancer
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Total 60720 results found since Jan 2013.
Twenty-Year Follow-Up of a Phase II Trial of Taxotere/Carboplatin/Herceptin in Patients With Metastatic HER2-Positive Breast Cancer
CONCLUSION: A subset of patients (10%) receiving trastuzumab in the metastatic setting have achieved long-term survival beyond 20 years.PMID:37725049 | DOI:10.1093/oncolo/oyad258
Source: The Oncologist - September 19, 2023 Category: Cancer & Oncology Authors: Juan Luis Gomez Marti Azadeh Nasrazadani Ying Ding Daniel Normolle Adam M Brufsky Source Type: research
Design and Synthesis of New bis-oxindole and Spiro(triazole-oxindole) as CDK4 Inhibitors with Potent Anti-breast Cancer Activity
CONCLUSION: According to all of the findings, bis-oxindole 3c shows promise as a cancer treatment targeting CDK4.PMID:37723960 | DOI:10.2174/1573406419666230810124855
Source: Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Thoraya A Farghaly Rami Adel Pashameah Abrar Bayazeed Amerah M Al-Soliemy Amani M R Alsaedi Marwa F Harras Source Type: research
Accessory breast cancer: A case report and literature review of ultrasonographic findings
Australas J Dermatol. 2023 Sep 18. doi: 10.1111/ajd.14160. Online ahead of print.NO ABSTRACTPMID:37723873 | DOI:10.1111/ajd.14160
Source: The Australasian Journal of Dermatology - September 19, 2023 Category: Dermatology Authors: Kazuki Ichihashi Akimasa Adachi Yasuyuki Sawada Source Type: research
The quality and clinical translation of radiomics studies based on MRI for predicting Ki-67 levels in patients with breast cancer
CONCLUSION: Ki-67 index is a common tumor biomarker with high clinical value. Radiomics is an ever-growing quantitative data-mining method helping predict tumor biomarkers from medical images. However, the quality of the reviewed studies evaluated by the RQS was not so satisfactory and there are ample opportunities for improvement. Open science and data, external validation, phantom study, publicly open radiomics database and standardization in the radiomics practice are what researchers should pay more attention to in the future.ADVANCES IN KNOWLEDGE: The RQS tool considered the radiomics used to predict the Ki-67 level w...
Source: The British Journal of Radiology - September 19, 2023 Category: Radiology Authors: Min Wang Ting Mei Youling Gong Source Type: research
Quality of evidence supporting the role of acupuncture for breast cancer-related lymphoedema: an overview of systematic reviews and meta-analyses
CONCLUSIONS: Acupuncture may be beneficial in improving BCRL. However, due to the identified limitations and conflicting findings, further more prescriptive and rigorous SRs/MAs are required to give strong evidence for final judgments.PMID:37721568 | DOI:10.1007/s00432-023-05419-1
Source: Clinical Breast Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Lei Wang Xueyuan Du Peng Hu Yaling Zhang Mingchao Yao Xiaoling Che Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Breast Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
Enhanced Photoacoustic Imaging of Urokinase-Type Plasminogen Activator Activity in Tumors
Anal Chem. 2023 Sep 18. doi: 10.1021/acs.analchem.3c03305. Online ahead of print.ABSTRACTPhotoacoustic (PA) imaging of urokinase-type plasminogen activator (uPA) activity in vivo holds high promise for early diagnosis of breast cancer. Molecular probes with resisted fluorescence (FL) emission for enhanced PA signals of uPA activity have not been reported. Herein, we proposed a molecular probe Cbz-Gly-Gly-Arg-Phe-Phe-IR775 (Z-GGRFF-IR775) which, upon uPA cleavage, assembled into nanoparticles FF-IR775-NP with quenched fluorescence but enhanced PA signals. Experimental results validated that, upon uPA activation, Z-GGRFF-IR7...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Xinyi Hu Xianbao Sun Xiaoyang Liu Hai-Dong Xu Liang Yang Songqin Liu Rui Wang Gaolin Liang Source Type: research
In Vitro and In Vivo Effects of Docetaxel and Dasatinib in Triple-Negative Breast Cancer: A Research Study
Conclusions TNBC is a difficult-to-treat oncologic condition, even in an experimental setting. Promising results concerning the addition of targeted therapies (dasatinib) to the conventional cytotoxic ones (docetaxel) have been shown, awaiting further evaluation.PMID:37719631 | PMC:PMC10500968 | DOI:10.7759/cureus.43534
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Ioannis D Passos Dimochristos Papadimitriou Areti Katsouda Georgios E Papavasileiou Apostolos Galatas Panagiotis Tzitzis Alexandra Mpakosi Maria Mironidou-Tzouveleki Source Type: research
Erratum to: Comprehensive serum lipidomic analyses reveal potential biomarkers for malignant breast cancer: A case-control study
Cancer Biomark. 2023 Sep 14. doi: 10.3233/CBM-239003. Online ahead of print.NO ABSTRACTPMID:37718782 | DOI:10.3233/CBM-239003
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Source Type: research
β-Glucan Regulates Lipopolysaccharide Induced Genotoxic Damage to The Liver through The Induction of BRCA1 Protein Expression
CONCLUSION: The results manifested that the βG is a strong inducer of the BRCA1 protein expression in the LPSinduced hepatic stress and the protein constitutes the key component of a βG mediated liver protection against an LPS-induced genotoxic and pathological damage.PMID:37718767 | DOI:10.22074/cellj.2023.1989382.1226
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: G özde Aydoğan Kılıç Mojahed Alsafi Source Type: research
Diagnostic performance of two versions of an artificial intelligence system in interval breast cancer detection
CONCLUSION: The present study showed that Tranpara v1.7 has a higher specificity, sensitivity and diagnostic performance in IBC determination than v1.6. AI systems can be used in breast screening as a secondary or third reader in screening programs.PMID:37722761 | DOI:10.1177/02841851231200785
Source: Acta Radiologica - September 18, 2023 Category: Radiology Authors: Levent Çelik Davut Can G üner Ömer Özçağlayan Rahmi Çubuk Mustafa Erkin Ar ıbal Source Type: research
Quality of evidence supporting the role of acupuncture for breast cancer-related lymphoedema: an overview of systematic reviews and meta-analyses
CONCLUSIONS: Acupuncture may be beneficial in improving BCRL. However, due to the identified limitations and conflicting findings, further more prescriptive and rigorous SRs/MAs are required to give strong evidence for final judgments.PMID:37721568 | DOI:10.1007/s00432-023-05419-1
Source: Clinical Genitourinary Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Lei Wang Xueyuan Du Peng Hu Yaling Zhang Mingchao Yao Xiaoling Che Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Genitourinary Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer
Res Sq. 2023 Sep 8:rs.3.rs-3266720. doi: 10.21203/rs.3.rs-3266720/v1. Preprint.ABSTRACTThe alternative splicing of PML precursor mRNA gives rise to various PML isoforms, yet their expression profile in breast cancer cells remains uncharted. We discovered that PML1 is the most abundant isoform in all breast cancer subtypes, and its expression is associated with unfavorable prognosis in estrogen receptor-positive (ER+) breast cancers. PML depletion reduces cell proliferation, invasion, and stemness, while heterologous PML1 expression augments these processes and fuels tumor growth and resistance to fulvestrant, an FDA-approv...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Hung-Ying Kao Chun-Peng Pai Han Wang Neel Agarwal Joshua Adams Zhenghao Liu Darcie Seachrist Ruth Keri William Schiemann Source Type: research
Erratum to: Comprehensive serum lipidomic analyses reveal potential biomarkers for malignant breast cancer: A case-control study
Cancer Biomark. 2023 Sep 14. doi: 10.3233/CBM-239003. Online ahead of print.NO ABSTRACTPMID:37718782 | DOI:10.3233/CBM-239003
Source: Cancer Biomarkers : Section A of Disease Markers - September 18, 2023 Category: Cancer & Oncology Source Type: research
