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Total 11 results found since Jan 2013.
The Conspirituality of Robert F. Kennedy Jr.
This article has been adapted from Chapter 23 of Conspirituality: How New Age Conspiracy Theories Became a Health Threat by Derek Beres, Matthew Remski, and Julian Walker. Copyright © 2023. Available from PublicAffairs, an imprint of Hachette Book Group, Inc.
Source: TIME: Health - July 5, 2023 Category: Consumer Health News Authors: Derek Beres, Matthew Remski, and Julian Walker Tags: Uncategorized freelance politics Source Type: news
Science ’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew
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Source: ScienceNOW - December 15, 2022 Category: Science Source Type: news
Anthony Fauci, 100 Days Into the Biden Administration, Is Finally Getting to Do His Job
When Dr. Anthony Fauci arrived at 1600 Pennsylvania Ave. for his first White House press briefing under the new Biden Administration, he could see things would be different.
It was the day after the Inauguration, and President Joe Biden was eager to get the country’s COVID-19 response back on track. Five minutes before he addressed the public, Fauci spoke with the new President. “He said, ‘I want you to just go and tell the science, explain to people that if we make mistakes, we’re going to fix the mistakes and we’re not going to dwell on the mistakes. Let science be communicated to the public...
Source: TIME: Health - May 18, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
NIH Slated for 7 percent Budget Cut
The President has proposed a $38.7 billion budget for the National Institutes of Health in fiscal year (FY) 2021. This translates to a $3 billion or 7 percent cut in the agency’s funding compared to FY 2020.
The NIH budget request includes a $50 million initiative to use artificial intelligence (AI) to develop a better understanding of the causes of chronic diseases and to identify early treatments. This plan is in line with the Administration’s “Industries of the Future” effort, which supports using and developing AI across sectors.
The budget would provide $50 million for the Childhood Cancer ...
Source: Public Policy Reports - February 18, 2020 Category: Biology Authors: AIBS Source Type: news
Functional Antibody Responses Following Allogeneic Stem Cell Transplantation for TP53 Mutant pre-B-ALL in a Patient With X-Linked Agammaglobulinemia
Discussion
This case demonstrates successful cure of pre-B-ALL complicating XLA by alloSCT with restoration of B-cell development and functional antibody response.
We are aware of only one previous case of pre-B-ALL in an XLA patient (21), which suggests that human BTK deficiency in itself does not predispose to pre-B-ALL. However, there are data to suggest that BTK may act as a tumor suppressor, and BTK deficiency may predispose to tumor development following a “second hit.” Mice with a genetic deficiency in Slp65, a gene encoding an adaptor protein that functions together with BTK, have a block in proge...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research
A Gene Therapy Breakthrough Could Offer a Treatment for the Rare and Deadly ‘Bubble Boy’ Disease
Researchers used an experimental gene therapy to develop a possible treatment for a rare and deadly immune disorder known as “bubble boy” disease, the National Institutes of Health (NIH) announced Wednesday.
Because of a gene mutation, babies who are born with X-linked severe combined immunodeficiency (X-SCID) do not develop immune cells properly, leaving them highly susceptible to infections. The condition, which strikes up to one in 50,000 newborns, primarily affects boys and requires extreme measures to prevent infection. In one famous case, a boy with SCID, David Vetter, lived in a sterile plastic “bu...
Source: TIME: Health - April 18, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Research Source Type: news
Editorial: Shaping of Human Immune System and Metabolic Processes by Viruses and Microorganisms
Conclusions
In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases.
Author Contributions
All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - April 16, 2019 Category: Microbiology Source Type: research
Beyond CAR T Cells: Other Cell-Based Immunotherapeutic Strategies Against Cancer
Conclusions: CAR T cell therapies have demonstrated the clinical benefits of harnessing our body's own defenses to combat tumor cells. Similar research is being conducted on lesser known modifications and gene-modified immune cells, which we highlight in this review.
Introduction
Chimeric antigen receptors and engineered T cell receptors (based on previously identified high affinity T cell receptors) function by redirecting T cells to a predefined tumor-specific (or tumor-associated) target. Most of these modifications use retroviral or lentiviral vectors to integrate the construct, and most of the receptors ...
Source: Frontiers in Oncology - April 9, 2019 Category: Cancer & Oncology Source Type: research
Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies
Conclusions:
Arsenic exposure increased tIgG and tIgE in plasma, and tended to decrease mumps-specific IgG in children at 9 years of age. https://doi.org/10.1289/EHP318
Received: 09 April 2016
Revised: 09 October 2016
Accepted: 24 October 2016
Published: 14 June 2017
Address correspondence to R. Raqib, Immunobiology, Nutrition and Toxicology Laboratory, Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Mohakhali, Dhaka-1212, Bangladesh. Telephone: 880-2-9827068. E-mail: rubhana@icddrb.org
Supplemental Material is available online (https://doi.org/10.1289/EHP318).
The authors declare they have n...
Source: EHP Research - June 15, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Research Source Type: research
Developing immunotherapies for childhood cancer
Introduction The development of immune-based treatment (immunotherapy) for childhood cancer is a rapidly advancing field with impressive results already achieved in children with leukaemia.1 2 For cancers resistant to conventional treatments, harnessing the power and specificity of the immune system to fight cancer is one of several current avenues of research. The immune system is essential for controlling cancer progression by continual surveillance and elimination of transformed cells. This protective process is hindered by the ability of cancer cells to develop mechanisms enabling them to ‘hide’ from immune...
Source: Archives of Disease in Childhood - Education and Practice - May 16, 2017 Category: Pediatrics Authors: Capsomidis, A., Anderson, J. Tags: Oncology, Immunology (including allergy), Drugs: infectious diseases, Vaccination / immunisation, Dermatology, Guidelines Research in practice Source Type: research
Immunisation against HPV in girls with intellectual disabilities
Since September 2008 in the UK, immunisation against human papillomavirus (HPV) has been routinely offered to all girls aged 12–13 years as part of the childhood immunisation programme. It has been shown in previous research, that children attending schools for children and young people with intellectual disability are less likely to receive routine vaccines compared with non-disabled peers.1 Unpublished data from an audit carried out in the Portsmouth district suggests similar issues for HPV vaccination. This paper looks at what we know about HPV infection and the risks to individuals with intellectual disabili...
Source: Archives of Disease in Childhood - November 13, 2014 Category: Pediatrics Authors: MacLeod, R., Tuffrey, C. Tags: Oncology, Epidemiologic studies, Immunology (including allergy), Drugs: infectious diseases, Vaccination / immunisation, Cervical cancer, Cervical screening, Adolescent health, Child and adolescent psychiatry (paedatrics), Child health, Disability, Screen Source Type: research
