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Total 138 results found since Jan 2013.
Cardiac comorbidity in head and neck cancer patients and its influence on cancer treatment selection and mortality: a prospective cohort study
AbstractComorbidity assessment and a profound cardiac examination were implemented into pre-treatment diagnostics to analyze their influence on head and neck squamous cell carcinoma (HNSCC) therapy selection and short-term mortality. Comorbidity was measured prospectively in 49 HNSCC patients using standard indices between 2012 and 2013. Cardiac examinations included electrocardiogram, echocardiography, and bicycle ergometry. Most patients had stage IV tumors (61 %), smoked (61 %), and showed alcohol abuse (57 %); 38 patients (78 %) received a multimodal therapy; 65 % had an adult comorbidity evaluation 27 index ≥2...
Source: European Archives of Oto-Rhino-Laryngology - August 4, 2016 Category: ENT & OMF Source Type: research
Intracranial hypertension as the primary symptom of gastric signet-ring cell carcinoma: A case report and literature review
Conclusion: To our knowledge, this is the first reported case of gastric signet-ring cell carcinoma primarily presenting IH and accompanied by subcutaneous metastases. This case emphasizes the importance of excluding malignancy from the differential diagnosis of IH.
Source: Medicine - August 1, 2016 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
E-067 Endovascular Approach in the Repair of the Middle Cerebral Artery Aneurysm Including Those with Wide Neck and Complex in Morphology-A Case Series
ConclusionsEndovascular repair of the MCA aneurysm inclosing those with wide neck and complex are not only safe and feasible, but associated with high long-term functional outcome. Therefore, endovascular options must be offered to patients prior to surgical clipping of a MCA aneurysm. Further study may be warranted.DisclosuresY. Lodi: None. V. Reddy: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Lodi, Y., Reddy, V. Tags: Electronic poster abstracts Source Type: research
Stroke after Radiotherapy for Head and Neck Cancer – What is the Risk?
Treating head and neck squamous cell carcinomas with radiotherapy has been shown to cause damage to the cerebrovasculature. This retrospective cohort study found that any exposure to radiation was associated with a 46% higher hazard of stroke, and with radiotherapy as the sole treatment modality, 70% increased risk of stroke compared to surgery alone. Implications of this research speak to the need for adequate follow-up and survivorship care among patients that were treated with RT.
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Source Type: research
Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC).
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Tags: Clinical Investigation Source Type: research
EPMA-World Congress 2015
Table of contents
A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma
Jella-Andrea Abraham, Olga Golubnitschaja
A2 Integrated market access approach amplifying value of “Rx-CDx”
Ildar Akhmetov
A3 Disaster response: an opportunity to improve global healthcare
Russell J. Andrews, Leonidas Quintana
A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy
Russell J. Andrews
A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research
Discovery of a Novel Anti-Cancer Agent Targeting Both Topoisomerase I & II as well as Telomerase Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo: Cinnamomum verum Component Cuminaldehyde.
Discovery of a Novel Anti-Cancer Agent Targeting Both Topoisomerase I & II as well as Telomerase Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo: Cinnamomum verum Component Cuminaldehyde.
Curr Cancer Drug Targets. 2016 Apr 26;
Authors: Chen TW, Tsai KD, Yang SM, Wong HY, Liu YH, Cherng J, Chou KS, Wang YT, Cuizon J, Cherng JM
Abstract
Cinnamomum verum is used to make the spice cinnamon and has been used for more than 5000 years by both of the two most ancient forms of medicine in the words: Ayurveda and traditional Chinese herbal medicines for various applications such as a...
Source: Current Cancer Drug Targets - April 25, 2016 Category: Cancer & Oncology Authors: Chen TW, Tsai KD, Yang SM, Wong HY, Liu YH, Cherng J, Chou KS, Wang YT, Cuizon J, Cherng JM Tags: Curr Cancer Drug Targets Source Type: research
Radiotherapy Induced Atherosclerosis and Stroke Syndrome (RIASS) Causing Bilateral Vision Loss and Multifocal Strokes. A Case Report and Literature Review (P4.358)
Conclusions: Evidence-based guidelines for the management of asymptomatic and symptomatic RIASS are lacking. We recommend periodic surveillance with carotid duplex scan for early diagnosis and implementation of effective stroke-prevention therapies. Most studies are retrospective surgical case series on patients with extracranial carotid stenosis (ECS) and favor either stenting or endarterectomy. Neither approach is clearly superior, as no head-to-head trial comparing both procedures in this context exists. Bypass surgery has been used in cases of HNXRT associated ECS but the long term effect has not been demonstrated. Aty...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rathore, J., Ali, M., Ulanski, L., Testai, F. Tags: Cerebrovascular Case Reports Source Type: research
Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study Stroke
Conclusions
Our data provide strong support for future studies on the role of PTCSC3 in the pathogenesis of LAA stroke and the association between LAA stroke development and thyroid function. In addition, these findings provide insights into the genetic basis of LAA stroke and identify a novel pathway that might be applicable for future therapeutic intervention.
Source: JAHA:Journal of the American Heart Association - March 28, 2016 Category: Cardiology Authors: Lee, T.-H., Ko, T.-M., Chen, C.-H., Lee, M.-T. M., Chang, Y.-J., Chang, C.-H., Huang, K.-L., Chang, T.-Y., Lee, J.-D., Chang, K.-C., Yang, J.-T., Wen, M.-S., Wang, C.-Y., Chen, Y.-T., Hsieh, C.-S., Chou, S.-Y., Liu, Y.-M., Chen, H.-W., Liao, H.-T., Wang, Tags: Genetic, Association Studies, Ischemic Stroke Source Type: research
Cardiovascular Disease Among Survivors of Adult-Onset Cancer: A Community-Based Retrospective Cohort Study Epidemiology
Conclusion
The magnitude of subsequent CVD risk varies according to cancer subtype and by the presence of CVRFs. Overall survival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies for individuals at highest risk of developing CVD.
Source: Journal of Clinical Oncology - March 22, 2016 Category: Cancer & Oncology Authors: Armenian, Xu, Ky, Sun, Farol, Pal, Douglas, Bhatia, Chao Tags: Population and observational studies (SEER, WHI observational, etc.) Epidemiology Source Type: research
Cardiovascular Disease Among Survivors of Adult-Onset Cancer: A Community-Based Retrospective Cohort Study.
CONCLUSION: The magnitude of subsequent CVD risk varies according to cancer subtype and by the presence of CVRFs. Overall survival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies for individuals at highest risk of developing CVD.
PMID: 26834065 [PubMed - as supplied by publisher]
Source: Clinical Prostate Cancer - February 1, 2016 Category: Cancer & Oncology Authors: Armenian SH, Xu L, Ky B, Sun C, Farol LT, Pal SK, Douglas PS, Bhatia S, Chao C Tags: J Clin Oncol Source Type: research
ConnectViz : Accelerated Approach for Brain Structural Connectivity Using Delaunay Triangulation
This study proposes an accelerated approach for brain connectomic visualization based on graph theory paradigm using compute unified device architecture, extending the previously proposed SurLens Visualization and computer aided hepatocellular carcinoma frameworks. The accelerated brain structural connectivity framework was evaluated with stripped brain datasets from the Department of Surgery, University of North Carolina, Chapel Hill, USA. Significantly, our proposed framework is able to generate and extract points and edges of datasets, displays nodes and edges in the datasets in form of a network and clearly maps data v...
Source: Interdisciplinary Sciences, Computational Life Sciences - January 14, 2016 Category: Bioinformatics Source Type: research
Massive Epistaxis from Internal Carotid Pseudoaneurysm during Acute Ischemic Stroke in a Patient with Nasopharyngeal Carcinoma.
CONCLUSION: Carotid blowout syndrome in NPC patients during acute ischemic stroke warrants further cervical angiographic study. Endovascular treatment provides immediate hemostasis and obliteration of ICA pseudoaneurysm.
PMID: 26077184 [PubMed - indexed for MEDLINE]
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research
Dementia Risk in Irradiated Patients With Head and Neck Cancer
This study estimated the dementia risk associated with different treatment modalities in a head and neck cancer population with long-term follow-up.
Taiwan's National Health Insurance claims database and a cancer registry database from the Collaboration Center of Health Information Application were linked for the present analysis. Patients with head and neck cancer, treated from January 1, 2002 to December 31, 2010, were included in the study. The follow-up duration was the period from the index date to December 31, 2012. Inclusion criteria were head and neck cancer; an age>20 years; and having undergone surgery, CT, concu...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
