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Total 352 results found since Jan 2013.

State Prisons Need More Smoking-Cessation Programs: Study
MONDAY, Feb. 4, 2019 -- Many inmates in U.S. state prisons who want to quit smoking have nowhere to turn for help, a new study finds. That increases their risk of smoking-related diseases, including cancer, heart disease and stroke. And the risk is...
Source: Drugs.com - Daily MedNews - February 4, 2019 Category: General Medicine Source Type: news

Exercise Your Right to Fight Disease
MONDAY, Feb. 4, 2019 -- Research consistently tells you just how important exercise is for health. It can help head off heart disease, stroke, diabetes and many types of cancer, including breast and colon cancers. A report published in the New...
Source: Drugs.com - Daily MedNews - February 4, 2019 Category: General Medicine Source Type: news

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
Publication date: 2–8 February 2019Source: The Lancet, Volume 393, Issue 10170Author(s): Jane Armitage, Colin Baigent, Elizabeth Barnes, D John Betteridge, Lisa Blackwell, Michael Blazing, Louise Bowman, Eugene Braunwald, Robert Byington, Christopher Cannon, Michael Clearfield, Helen Colhoun, Rory Collins, Björn Dahlöf, Kelly Davies, Barry Davis, James de Lemos, John R Downs, Paul Durrington, Jonathan EmbersonSummaryBackgroundStatin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We u...
Source: The Lancet - February 2, 2019 Category: General Medicine Source Type: research

General health checks in adults for reducing morbidity and mortality from disease.
CONCLUSIONS: General health checks are unlikely to be beneficial. PMID: 30699470 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 31, 2019 Category: General Medicine Authors: Krogsbøll LT, Jørgensen KJ, Gøtzsche PC Tags: Cochrane Database Syst Rev Source Type: research

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses
Publication date: Available online 10 January 2019Source: The LancetAuthor(s): Andrew Reynolds, Jim Mann, John Cummings, Nicola Winter, Evelyn Mete, Lisa Te MorengaSummaryBackgroundPrevious systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have usually examined a single marker and a limited number of clinical outcomes. We aimed to more precisely quantify the predictive potential of several markers, to determine which markers are most useful, and to establish an evidence base for quantitative recommendations for intakes of dietary fibre.MethodsWe did a series of systema...
Source: The Lancet - January 11, 2019 Category: General Medicine Source Type: research

Heart Risks High in Older Cancer Patients Before Diagnosis
FRIDAY, Dec. 21, 2018 -- There ' s a significant rise in the risk of heart attack and stroke in older people in the months before they ' re diagnosed with cancer, a new study finds. " Our data show there is an associated risk of ischemic stroke and heart...
Source: Drugs.com - Daily MedNews - December 21, 2018 Category: General Medicine Source Type: news

Obesity and cardiovascular risk in an oncology day ward population
ConclusionsWe observed similar or lower rates of obesity and CV risk factors in this cohort compared to the general adult Irish population. The average predicted risk of developing CV disease in this grp was moderate to high. This can have significant future implications with regard to cancer survivorship, disease recurrence and suitability for further oncological treatments.
Source: Irish Journal of Medical Science - December 18, 2018 Category: General Medicine Source Type: research

Ezetimibe for the prevention of cardiovascular disease and all-cause mortality events.
CONCLUSIONS: Moderate- to high-quality evidence suggests that ezetimibe has modest beneficial effects on the risk of CVD endpoints, primarily driven by a reduction in non-fatal MI and non-fatal stroke, but it has little or no effect on clinical fatal endpoints. The cardiovascular benefit of ezetimibe might involve the reduction of LDL-C, total cholesterol and triglycerides. There is insufficient evidence to determine whether ezetimibe increases the risk of adverse events due to the low and very low quality of the evidence. The evidence for beneficial effects was mainly obtained from individuals with established atheroscler...
Source: Cochrane Database of Systematic Reviews - November 19, 2018 Category: General Medicine Authors: Zhan S, Tang M, Liu F, Xia P, Shu M, Wu X Tags: Cochrane Database Syst Rev Source Type: research

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
Publication date: 10–16 November 2018Source: The Lancet, Volume 392, Issue 10159Author(s): Gregory A Roth, Degu Abate, Kalkidan Hassen Abate, Solomon M Abay, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Haftom Temesgen Abebe, Molla Abebe, Zegeye Abebe, Ayenew Negesse Abejie, Semaw F Abera, Olifan Zewdie Abil, Haftom Niguse Abraha, Aklilu Roba AbrhamSummaryBackgroundGlobal development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden ...
Source: The Lancet - November 11, 2018 Category: General Medicine Source Type: research

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
This study is registered with ClinicalTrials.gov, number NCT02465515.FindingsPatients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat popu...
Source: The Lancet - October 5, 2018 Category: General Medicine Source Type: research

Premature Deaths Attributable to Long-term Exposure to Ambient Fine Particulate Matter in the Republic of Korea.
Conclusion: Premature deaths due to long-term exposure to PM2.5 accounted for 6.4% of all deaths in Korea. However, individual efforts alone cannot prevent the effects of air pollution. This disease burden study can serve as a basis for the establishment of government policies and budgets and can be used to assess the effectiveness of environmental health policies. PMID: 30190659 [PubMed - in process]
Source: J Korean Med Sci - September 8, 2018 Category: General Medicine Authors: Kim JH, Oh IH, Park JH, Cheong HK Tags: J Korean Med Sci Source Type: research

The burden of disease in Spain: Results from the Global Burden of Disease 2016.
CONCLUSION: Low back and neck pain was the most important contributor of disability in Spain in 2016. There has seen a remarkable increase in the burden due to Alzheimer disease and other dementias. Tobacco remains the most important health issue to address in Spain. PMID: 30037695 [PubMed - as supplied by publisher]
Source: Medicina Clinica - July 26, 2018 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Spatial and Temporal Trends of Number of Deaths Attributable to Ambient PM2.5 in the Korea.
Conclusion: Our findings show that further actions to improve air quality in Korea would substantially improve the health burden due to particulate matter. PMID: 30034305 [PubMed - in process]
Source: J Korean Med Sci - July 23, 2018 Category: General Medicine Authors: Han C, Kim S, Lim YH, Bae HJ, Hong YC Tags: J Korean Med Sci Source Type: research

Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials
Publication date: Available online 17 July 2018Source: The LancetAuthor(s): Peter M Rothwell, Nancy R Cook, J Michael Gaziano, Jacqueline F Price, Jill F F Belch, Maria Carla Roncaglioni, Takeshi Morimoto, Ziyah MehtaSummaryBackgroundA one-dose-fits-all approach to use of aspirin has yielded only modest benefits in long-term prevention of cardiovascular events, possibly due to underdosing in patients of large body size and excess dosing in patients of small body size, which might also affect other outcomes.MethodsUsing individual patient data, we analysed the modifying effects of bodyweight (10 kg bands) and height (10 cm ...
Source: The Lancet - July 18, 2018 Category: General Medicine Source Type: research

CMS Requirements for Mandatory Shared Decision Making for Cardiac Procedures and Other Tests
This Viewpoint discusses Centers for Medicare& Medicaid Services (CMS) policies requiring physicians to engage patients in shared decision making prior to implantation of an implantable cardioverter-defibrillator, lung cancer screening, and left atrial appendage closure for stroke prevention in atrial fibrillation, and argues that better guidance is needed if the requirements are to promote meaningful shared decisions.
Source: JAMA - Journal of the American Medical Association - June 4, 2018 Category: General Medicine Source Type: research