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Specialty: Cancer & Oncology
Cancer: Cancer

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Total 908 results found since Jan 2013.

Androgen Deprivation Therapy and Risk of Cardiovascular Disease in Patients With Prostate Cancer Based on Existence of Cardiovascular Risk
CONCLUSIONS: Compared with GnRH agonists, the GnRH antagonist was found to be associated with a decreased risk of HF, specifically among patients with prior CVD. Among those with no prior CVD, the GnRH antagonist was associated with a decreased risk of IHD but an increased risk of arrhythmia.PMID:36791755 | DOI:10.6004/jnccn.2022.7083
Source: Journal of the National Comprehensive Cancer Network : JNCCN - February 15, 2023 Category: Cancer & Oncology Authors: Alice Dragomir Nawar Touma Jason Hu Sylvie Perreault Armen G Aprikian Source Type: research

Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?
In conclusion, the mutual regulation of autophagy and inflammation in ICH is worth exploring. The control of inflammation by autophagy will hopefully prove to be an essential treatment target for ICH.PMID:36726453 | PMC:PMC9884704 | DOI:10.3389/fncel.2022.1036313
Source: Cancer Control - February 2, 2023 Category: Cancer & Oncology Authors: Kaijing Fu Weilin Xu Cameron Lenahan Yong Mo Jing Wen Teng Deng Qianrong Huang Fangzhou Guo Ligen Mo Jun Yan Source Type: research

Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry
ConclusionAlthough the survival of LS patients with PC or BTC is better than in sporadic cancers, it is still poor and may be reflected by the relatively higher surgical resectability accounted for by the earlier age of onset. More studies on analyses of the molecular and immune profile, screening, and management of LS-associated pancreaticobiliary cancers are warranted.
Source: Frontiers in Oncology - February 1, 2023 Category: Cancer & Oncology Source Type: research

Vitamin D intake and all-cause and cause-specific mortality in Japanese men and women: the Japan Public Health Center-based prospective study
Eur J Epidemiol. 2023 Jan 31. doi: 10.1007/s10654-023-00968-8. Online ahead of print.ABSTRACTWhile higher circulating 25-hydroxyvitamin D concentrations have been reported to be associated with decreased risk of all-cause mortality, evidence on dietary vitamin D intake is limited and inconsistent. We investigated whether vitamin D intake is associated with all-cause and cause-specific mortality among Japanese adults. Participants were 42,992 men and 50,693 women who responded to the second survey of the Japan Public Health Center-based Prospective Study (1995-1998) and who were followed up for mortality through 2018. Dieta...
Source: Cancer Control - January 31, 2023 Category: Cancer & Oncology Authors: Akiko Nanri Tetsuya Mizoue Atsushi Goto Mitsuhiko Noda Norie Sawada Shoichiro Tsugane Japan Public Health Center-based Prospective Study Group Source Type: research

Recognizing the True Value of Testosterone Therapy in Health Care
Androg Clin Res Ther. 2022 Dec 28;3(1):217-223. doi: 10.1089/andro.2022.0021. eCollection 2022.ABSTRACTThere has been little recognition within the medical community of the health impact of testosterone (T) deficiency (TD), also known as hypogonadism, and the substantial benefits of testosterone therapy (TTh) on health and quality of life despite high-level clinical evidence. In a roundtable symposium, investigators summarized the contemporary evidence in several key clinical areas. TD negatively impacts human health and quality of life and is associated with increased mortality. Several studies have demonstrated that TTh ...
Source: Clinical Prostate Cancer - January 16, 2023 Category: Cancer & Oncology Authors: Abraham Morgentaler Abdulmaged Traish Rajat S Barua Paresh Dandona Sandeep Dhindsa Mohit Khera Farid Saad Source Type: research

High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: Findings from a population-based cohort
This study assessed whether in a population with comorbidity of neurodegenerative and cerebrovascular disease (mixed pathology) the association of glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and phosphorylated tau181 (p-tau181) with dementia risk varied depending on levels of total cholesterol and apolipoprotein E (APOE) ε4 genotype.METHODS: Plasma biomarkers were measured using Simoa technology in 768 participants of a nested case-control study embedded within an ongoing population-based cohort. Logistic and spline regression models, and receiver operating characteristic curves were calculate...
Source: Cancer Control - January 13, 2023 Category: Cancer & Oncology Authors: Laura Perna Ute Mons Hannah Stocker L éon Beyer Konrad Beyreuther Kira Trares Bernd Holleczek Ben Sch öttker Robert Perneczky Klaus Gerwert Hermann Brenner Source Type: research

Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative
CONCLUSION: Among postmenopausal Hispanic women with overweight, greater adherence to pro-inflammatory diets was associated with higher risk of CVD. Additional research is needed to understand how to promote long-term heart-healthy dietary habits to reduce inflammation and prevent CVD in at-risk Hispanic women.PMID:36631866 | DOI:10.1186/s12937-023-00838-9
Source: Cancer Control - January 11, 2023 Category: Cancer & Oncology Authors: Monica D Zuercher Danielle J Harvey Margarita Santiago-Torres Lauren E Au Nitin Shivappa Aladdin H Shadyab Matthew Allison Linda Snetselaar Buyun Liu John A Robbins James R H ébert Lorena Garcia Source Type: research

Enablers & amp; challenges of tribal women & amp; health system for implementation of screening of non-communicable diseases & amp; common cancers: A mixed-methods study in Palghar district of Maharashtra, India
CONCLUSIONS: The study recommends incorporating socioculturally relevant strategies in the tribal population and strengthening health facilities in terms of infrastructure and training with involvement of ASHAs for successful implementation of the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) through health and wellness centres.PMID:36629192 | DOI:10.4103/ijmr.ijmr_3240_21
Source: Cancer Control - January 11, 2023 Category: Cancer & Oncology Authors: Shantanu Birje Anushree Devashish Patil Kiran Ramdas Munne Vidya Chavan Beena Nitin Joshi Anamika Akula Neha Salvi Smitha Nair Shahanara Prabhu Valawalkar Deepti Tandon Sanjay Chauhan Devendra Patil Bontha V Babu Source Type: research

Multi-omics reveals specific host metabolism-microbiome associations in intracerebral hemorrhage
In conclusion, microbiome-related metabolites in ICH patients was associated with the severity of ICH, the microbiota-host co-metabolites may be a potential may be potential therapeutic targets.PMID:36619742 | PMC:PMC9813413 | DOI:10.3389/fcimb.2022.999627
Source: Cancer Control - January 9, 2023 Category: Cancer & Oncology Authors: Lei Chen Sai Wang Yupeng Zhang Ye Li Xiangbin Zhang Junyi Ma Xuelun Zou TianXing Yao Si Li Junyou Chen Huifang Zhou Lianxu Wu Yanhong Zhou Le Zhang Source Type: research

Predicted cardiac and second cancer risks for patients undergoing VMAT for mediastinal Hodgkin lymphoma
ConclusionFor patients with mediastinal lymphoma excess mortality risks from CVD and second cancers remain clinically significant despite contemporary chemotherapy and photon-RT. Efforts to reduce the toxicity of combined modality treatment, for example, using DIBH, reduced margins and advanced RT, e.g. proton beam therapy, should be continued to further reduce potentially fatal treatment effects.
Source: Clinical and Translational Oncology - December 31, 2022 Category: Cancer & Oncology Source Type: research

Association between peripheral blood cytopenia and cancer mortality: A race ‐specific risk factor for cancer death
ConclusionIn this large, observational biracial prospective study, cytopenia was a risk factor for cancer death, with stronger association in Black than White people. Though race impacted the association of cytopenia with cancer mortality, cytopenia was not a mediator of the racial disparity in cancer mortality.
Source: Cancer Medicine - December 30, 2022 Category: Cancer & Oncology Authors: Diego A. Adrianzen ‐Herrera, Insu Koh, Radhika Gangaraju, Tomi Akinyemiju, Neil A. Zakai Tags: RESEARCH ARTICLE Source Type: research

Predicted cardiac and second cancer risks for patients undergoing VMAT for mediastinal Hodgkin lymphoma
CONCLUSION: For patients with mediastinal lymphoma excess mortality risks from CVD and second cancers remain clinically significant despite contemporary chemotherapy and photon-RT. Efforts to reduce the toxicity of combined modality treatment, for example, using DIBH, reduced margins and advanced RT, e.g. proton beam therapy, should be continued to further reduce potentially fatal treatment effects.PMID:36585562 | DOI:10.1007/s12094-022-03034-z
Source: Clinical Genitourinary Cancer - December 30, 2022 Category: Cancer & Oncology Authors: Orla A Houlihan Georgios Ntentas David J Cutter Patricia Daly Charles Gillham Orla McArdle Frances K Duane Source Type: research