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Total 166 results found since Jan 2013.

Finding Power in My Panic Attacks
Trouble started in the form of rivulets of sweat dampening the waistband of my underwear. It was a bluebird afternoon in Phoenix in December of 2020, mid 60s, desert dry, and my heart was jackhammering against my ribcage. Breathing felt like I was sucking air through a stir straw. A small ABC News crew was arrayed before me, ready to broadcast the report I’d written that day, but with my vision narrowed to a needle’s eye, I could barely see them. I tried to swallow away the sandiness in my mouth but realized I’d forgotten how. [time-brightcove not-tgx=”true”] “I can’t swallow!...
Source: TIME: Health - September 12, 2023 Category: Consumer Health News Authors: Matt Gutman Tags: Uncategorized freelance Source Type: news

Aflatoxins posing threat to food safety and security in Pakistan: Call for a one health approach
Food Chem Toxicol. 2023 Aug 29:114006. doi: 10.1016/j.fct.2023.114006. Online ahead of print.ABSTRACTAflatoxins are among the most important mycotoxins due to their widespread occurrence and adverse impacts on humans and animals. These toxins and/or their metabolites cannot be destroyed with cooking or boiling methods. Therefore, consumption of aflatoxin-contaminated food may lead to impaired growth, compromised immunity, stomach and liver cancer, and acute toxicity. These adverse effects along with food wastage might have detrimental consequences on a country's economy. Several studies from Pakistan reported a high preval...
Source: Food and Chemical Toxicology - August 31, 2023 Category: Food Science Authors: Waseela Ashraf Abdul Rehman Masood Rabbani Waseem Shaukat Jia-Sheng Wang Source Type: research

"Is free-roaming a key factor determining lifespan? An epidemiological study on the life expectancy of Turkish companion dogs"
Res Vet Sci. 2023 Jul 10;162:104953. doi: 10.1016/j.rvsc.2023.104953. Online ahead of print.ABSTRACTCompanion dog lifespan data has exclusively been studied in developed economies. Here we report results from n = 1312 privately owned Turkish companion dogs (Free-roaming and non Free-roaming) from an online survey analyzed through Kaplan-Meier analysis and Cox regression. Median survival time (MST) was 13 years. Most common causes of death were viral infections (n = 126), cancer (n = 60), and cardiovascular disease (n = 36). Desexing (χ2 = 31.6, P = 2E-8), being a mixed breed (χ2 = 6.4, P = 0.01), and regular preventative...
Source: Cancer Control - July 28, 2023 Category: Cancer & Oncology Authors: Anil Demeli Silvan R Urfer Source Type: research

The prevalences and levels of occupational exposure to dusts and/or fibres (silica, asbestos and coal): A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury
CONCLUSIONS: Overall, we judged the bodies of evidence for occupational exposure to silica to vary by industrial sector between very low and moderate quality of evidence for prevalence, and very low and low for level. For occupational exposure to asbestos, the bodies of evidence varied by industrial sector between very low and low quality of evidence for prevalence and were of very low quality of evidence for level. For occupational exposure to coal dust, the bodies of evidence were of very low or moderate quality of evidence for prevalence, and low for level. None of the included studies were population-based studies (i.e...
Source: Cancer Control - July 24, 2023 Category: Cancer & Oncology Authors: Vivi Schl ünssen Daniele Mandrioli Frank Pega Natalie C Momen Bal ázs Ádám Weihong Chen Robert A Cohen Lode Godderis Thomas G öen Kishor Hadkhale Watinee Kunpuek Jianlin Lou Stefan Mandic-Rajcevic Federica Masci Ben Nemery Madalina Popa Natthadanai R Source Type: research

Macroeconomics and health: Understanding the impact of a declining economy on health outcomes of children and young adults in South Africa
CONCLUSIONS: Economic decline worsen mental health conditions, metabolic risk factors, and non-communicable conditions. The South African government may want to prioritize these conditions as covid-19 economic shocks continue to backslide economic growth.PMID:37155486 | PMC:PMC10116162 | DOI:10.1016/j.ssmph.2023.101404
Source: Cancer Control - May 8, 2023 Category: Cancer & Oncology Authors: Cyprian M Mostert Source Type: research

Day surgery unit robotics thoracic surgery: feasibility and management
CONCLUSION: Before this, day surgery and robotics assistant surgery in thoracic surgery had been proved feasibility and safety. However, there was no report of day surgery unit robotics assistant thoracic surgery. Our clinical practice demonstrated that the method of day surgery unit robotics thoracic surgery is feasibility and safety enough.PMID:37037929 | DOI:10.1007/s00432-023-04731-0
Source: Clinical Lung Cancer - April 10, 2023 Category: Cancer & Oncology Authors: Xin Li Yuanqi Liu Yanwu Zhou Yang Gao Chaojun Duan Chunfang Zhang Source Type: research

Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
Signal Transduct Target Ther. 2023 Apr 7;8(1):149. doi: 10.1038/s41392-023-01408-5.ABSTRACTHuman diseases, particularly infectious diseases and cancers, pose unprecedented challenges to public health security and the global economy. The development and distribution of novel prophylactic and therapeutic vaccines are the prioritized countermeasures of human disease. Among all vaccine platforms, viral vector vaccines offer distinguished advantages and represent prominent choices for pathogens that have hampered control efforts based on conventional vaccine approaches. Currently, viral vector vaccines remain one of the best st...
Source: Cancer Control - April 7, 2023 Category: Cancer & Oncology Authors: Shen Wang Bo Liang Weiqi Wang Ling Li Na Feng Yongkun Zhao Tiecheng Wang Feihu Yan Songtao Yang Xianzhu Xia Source Type: research

Empirical relationship between chromosomal damage and airborne particulate matter: A systematic review and meta-analysis of studies in exposed populations
Mutat Res Rev Mutat Res. 2023 Feb 12:108454. doi: 10.1016/j.mrrev.2023.108454. Online ahead of print.ABSTRACTAmbient particulate matter (PM) has gained significant attention as an environmental risk factor for human health. Although the association between ambient PM and micronucleus (MN) induction has been investigated, the quantitative association of PM and genomic instability is inconclusive. We conducted a systematic review and meta-analysis to study the association between PM exposure and MN endpoint. Four databases were systematically searched for studies published up to November 2022, to find papers investigating th...
Source: Cell Research - February 14, 2023 Category: Cytology Authors: Francisco Carlos da Silva Junior Leticya Pinto de Ara újo Jo ão Paulo de Mendonça Freitas Nilmara de Oliveira Alves Stefano Bonassi Silvia Regina Batistuzzo de Medeiros Source Type: research

Synthesis and antitumor activities of α-hydroxyamino phosphine oxides by catalyst-free hydrophosphinylation of nitrones
Chem Commun (Camb). 2023 Feb 10. doi: 10.1039/d2cc06981d. Online ahead of print.ABSTRACTInspired by the diverse bioactivities of α-amino phosphine oxides, an efficient strategy for the synthesis of less researched α-(hydroxyamino)diarylphosphine oxides has been developed and their antitumor activities are explored. Under water as a solvent and catalyst-free conditions, the addition of nitrones and diphenylphosphine oxide occurs smoothly to afford α-(hydroxyamino) diarylphosphine oxides in high yields. This reaction features a wide substrate scope, facile starting materials, atom economy, and easy purification. Moreover,...
Source: Chemical Communications - February 10, 2023 Category: Chemistry Authors: Pengfei Zhao Peiyuan Li Jian Xiao Yali Wang Xiaohui Hao Aiguo Meng Chunyan Liu Source Type: research

Cluster of resistance-inducing genes in MCF-7 cells by estrogen, insulin, methotrexate and tamoxifen extracted via NMF
Pathol Res Pract. 2023 Jan 30;242:154347. doi: 10.1016/j.prp.2023.154347. Online ahead of print.ABSTRACTBreast cancer has become a leading cause of death for women as the economy has grown and the number of women in the labor force has increased. Several biomarkers with diagnostic, prognostic, and therapeutic implications for breast cancer have been identified in studies, leading to therapeutic advances. Resistance, on the other hand, is one of clinical practice's limitations. In this paper, we use Nonnegative Matrix Factorization to automatically extract two gene signatures from gene expression profiles of wild-type and r...
Source: Pathology, Research and Practice - February 4, 2023 Category: Pathology Authors: Angelina Boccarelli Nicoletta Del Buono Flavia Esposito Source Type: research