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Total 164 results found since Jan 2013.
FDA permits marketing of new endoscopic device for treating gastrointestinal bleeding
The U.S. Food and Drug Administration permitted marketing of Hemospray, a new device used to help control certain types of bleeding in the gastrointestinal (GI) tract.“The device provides an additional, non-surgical option for treating upper and lower GI bleeding in certain patients, and may help reduce the risk of death from a GI bleed for many patients,” said Binita Ashar, M.D., director, division of surgical devices, in the FDA’s Center for Devices and R adiological Health.GI bleeding can occur in the upper GI tract (esophagus, stomach or small intestine) or the lower GI tract (colon and rectum). Causes of GI blee...
Source: Medical Hemostat - September 23, 2018 Category: Medical Devices Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs
GRGDS-functionalized chitosan nanoparticles as a potential intravenous hemostat for traumatic hemorrhage control in an animal model
Publication date: Available online 5 September 2018Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Pingyi Zhang, Subo Li, Shikun Zhang, Xue Zhang, Luming Wan, Zhimin Yun, Shouping Ji, Feng Gong, Manna Huang, Leilei Wang, Xinhai Zhu, Yingxia Tan, Yiqian WanAbstractHemostats, which are used for immediate intervention during internal hemorrhage in order to reduce resulting mortality and morbidity, are relatively rare. Here, we describe novel intravenous nanoparticles (CPG-NPs-2000) with chitosan succinate (CSS) as cores, polyethylene glycol (PEG-2000) as spacers and a glycine-arginine-glycine-aspartic aci...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - September 5, 2018 Category: Nanotechnology Source Type: research
In-vitro and in-vivo evaluation of hemostatic potential of decellularized ECM hydrogels
Publication date: Available online 6 August 2018Source: Materials LettersAuthor(s): Reiza D. Ventura, Andrew R. Padalhin, Byong Taek LeeAbstractExtracellular matrix (ECM) hydrogels with a porous microstructure and good swelling behavior were fabricated via lyophilization and cross-linked with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC). Platelet adhesion studies revealed that platelets easily adhered to hydrogels while coagulation studies showed rapid blood aggregate formation. In-vitro cytotoxicity studies showed ECM hydrogels are biocompatible. In-vivo studies using rat tail bleeding and rabbit arterial injury ...
Source: Materials Letters - August 7, 2018 Category: Materials Science Source Type: research
Combination treatment for cicatrix after neonatal circumcision: an office-based solution to a challenging problem
We present our successful experience that combines cicatrix stretching with a hemostat using local anesthesia in the office followed by several weeks of topical steroids with a minority of patients needing any additional therapy.
Source: Journal of Pediatric Urology - June 27, 2018 Category: Urology & Nephrology Authors: Seth A. Alpert, Christina B. Ching, Daniel G. DaJusta, Daryl J. McLeod, Molly E. Fuchs, Venkata R. Jayanthi Source Type: research
Sa1962 THE HEMOSTATIC EFFECT OF MUSSEL-INSPIRED CATECHOL ADHESIVE SHEET AFTER MUCOSECTOMY INDUCED ULCER: PORCINE EXPERIMENT
Gastrointestinal bleeding is the common problem in daily clinical practice. InnoSEAL Plus ® is a sheet-type hemostat that is made of a mussel-inspired catecholic adhesive material. It can stop a variety of bleedings in a coagulopathy independent manner. The aim of this study was to evaluate hemostatic efficacy of the catechol-adhesive sheet on gastric ulcer bleeding on porcine model.
Source: Gastrointestinal Endoscopy - May 30, 2018 Category: Gastroenterology Authors: In Kyung Yoo, Joo Young Cho, Sung-Pyo Hong Tags: Saturday abstract Source Type: research
Cook Medical wins FDA de novo nod for Hemospray
Cook Medical said yesterday it won FDA de novo clearance for its Hemospray endoscopic hemostat designed for treating bleeding in the gastrointestinal tract.
The Hemospray product won indications from the FDA for treating non-variceal GI bleeds, the Bloomington, Ind.-based company said. Hemospray is a single-use device designed to deliver an aerosolized spray of a mineral blend to a bleeding site during endoscopic procedures, and can cover large areas including ulcers and tumors, according to an FDA release.
“We are extremely pleased to receive this approval to market from FDA. We have worked diligently to bring a di...
Source: Mass Device - May 8, 2018 Category: Medical Devices Authors: Fink Densford Tags: Blood Management Endoscopic / Arthroscopic Food & Drug Administration (FDA) Regulatory/Compliance Cook Medical Source Type: news
4 Trends Advancing Medtech
For the past 20 years, the Medical Design Excellence Awards have celebrated medical products that improve the quality and accessibility of healthcare. Our finalists this year carry on this tradition, while also keeping in step with today’s high-tech digital and consumer trends.
With the help of our esteemed jurors, we have identified four key trends in this year’s group of finalists: risk reduction; faster, more-efficient healthcare delivery; the influence of the Internet of Things; and the consumerization of healthcare.
We’ve been tracking a few of these trends in past awards programs, so they’re not necessarily n...
Source: MDDI - April 27, 2018 Category: Medical Devices Authors: Daphne Allen Tags: MD & M East (New York) Design Source Type: news
Recombinant batroxobin-coated nonwoven chitosan as hemostatic dressing for initial hemorrhage control.
In conclusion, hemostasis can be improved by combining a chitosan-based nonwoven dressing with other agents, and rBat-coated chitosan-based nonwoven dressings have enormous potential to improve blood coagulation.
PMID: 29514041 [PubMed - as supplied by publisher]
Source: International Journal of Biological Macromolecules - March 4, 2018 Category: Biochemistry Authors: Seon GM, Lee MH, Kwon BJ, Kim MS, Koo MA, Seomun Y, Kim JT, Kim TH, Park JC Tags: Int J Biol Macromol Source Type: research
Hemostasis Solution Controls Bleeding during Surgery
A novel handheld device delivers a powder based on collagen to help surgeons achieve hemostatic bleeding control during surgical procedures.The Biom ’Up (Saint-Priest, France) HemoBlast Bellows is a sterile delivery device that is preloaded with a dry, sterile powder made of highly purified porcine collagen, glucose, chondroitin sulfate, and thrombin. The hemostatic powder is applied to the source of the bleeding by squeezing the bellows. Once applied, the powdered collagen and glucose components start the coagulation process by absorbing blood, concentrating coagulation factors and platelets, and providing a surface for...
Source: Medical Hemostat - January 2, 2018 Category: Medical Devices Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs
Hemostatic granules and dressing prepared from formulations of carboxymethyl cellulose, kappa-carrageenan and polyethylene oxide crosslinked by gamma radiation
In this study, we prepared biocompatible hydrogel-based hemostat crosslinked by ionizing radiation. Granules made from carboxymethyl cellulose and dressing from kappa carrageenan and polyethylene oxide were characterized by FT-IR, SEM, and gel analysis. Gamma radiation with a dose of 25kGy was used for sterilization process. Stability studies indicate that the products remain effective with a shelf life of up to 18 months based on accelerated aging. Both hemostatic agents were demonstrated to be effective in vitro blood clotting assays showing a low blood clotting index, high platelet adhesion capacity and accelerated clot...
Source: Radiation Physics and Chemistry - December 27, 2017 Category: Physics Source Type: research
Potent Hemostatic Efficacy of a Novel Recombinant Fibrin Sealant Patch (KTF-374) in Rabbit Bleeding Models.
CONCLUSIONS: These results suggest that KTF-374 possesses more potent hemostatic properties than FCCF for various patterns of bleeding. KTF-374 is a promising hemostat due to its potent efficacy and good visibility of the wound site through the patch.
PMID: 29260920 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - December 22, 2017 Category: Surgery Tags: J Invest Surg Source Type: research
Scientists Develop Squirtable Glue That Seals Wounds In Seconds
A potentially life-saving surgical glue that is highly elastic and adhesive can quickly seal wounds in seconds without the need for common staples or sutures.The surgical glue, called MeTro, is a development from biomedical engineers at the University of Sydney and biomedical engineers from Harvard University.MeTro has a high elasticity that can seal wounds in body tissues that need to expand and contract continuously, like the lungs, heart and arteries. Wounds on these types of tissues are prone to re-opening after sealing with staples and sutures.The glue is also beneficial for wounds that are in hard-to-reach places tha...
Source: Medical Hemostat - October 25, 2017 Category: Medical Devices Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs
Gecko Biomedical receives CE Mark Approval for SETALUM ™ Sealant
Paris, France, September 11, 2017 – Gecko Biomedical (“Gecko”), a medical device company developing innovative polymers to support tissue reconstruction, announced today that it has received CE Mark approval for its SETALUM™ Sealant allowing the company to market its technology in Europe.The SETALUM ™ Sealant is a biocompatible, bioresorbable and on-demand activated sealant usable in wet and dynamic environments as an add-on to sutures during vascular surgery. The polymer is applied to tissue in-situ and activated using a proprietary light activation pen.The technology at the foundation of the SETALUM ™ Sealant...
Source: Medical Hemostat - October 25, 2017 Category: Medical Devices Authors: hemostatguy at gmail.com (hemostat guy) Source Type: blogs
Comparison of 2 modified methods for the active removal of silicone oil with a 23-gauge transconjunctival vitrectomy system
Abstract To report and compare 2 modified approaches for the active removal of silicone oil (ROSO) with a 23-gauge transconjunctival vitrectomy system.
This prospective single blinded study was conducted from January 2015 to December 2016. Eighty-nine eyes of 86 patients who underwent silicone oil removal were enrolled. Patients were randomly divided into either group A or B. In group A, the fluid–air exchange tube was connected to a 1 mL syringe with the plunger removed and the tip was dilated with a hemostat so that it fit into the cap of the 23-gauge cannula to form a seal for oil drainage. In group B, the tip of t...
Source: Medicine - October 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Selective Stimulation of Facial Muscles Following Chronic Intraneural Electrode Array Implantation and Facial Nerve Injury in the Feline Model
Conclusion: We have established in the animal model the ability of a chronically implanted MEA to selectively stimulate restricted FN fiber populations and elicit activations in specific facial muscles. Likewise, after FN injury, selective stimulation of restricted FN fiber populations and subsequent activation of discrete facial muscles can be achieved after acute MEA implantation.
Source: Otology and Neurotology - September 16, 2017 Category: ENT & OMF Tags: Basic Science Source Type: research
