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SA55 Novel Coronavirus Broad-spectrum Neutralizing Antibody Nasal Spray in Health People
Condition:   COVID-19 Intervention:   Drug: SA55 nasal spray Sponsor:   Sinovac Life Sciences Co., Ltd. Recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

Omicron BA.4/5-Delta COVID-19 Vaccine Phase I Clinical Trial
Condition:   COVID-19 Interventions:   Biological: Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells);   Biological: Placebo Sponsors:   Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.;   Hunan Provincial Center for Disease Control and Prevention Not yet recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

SA55 Novel Coronavirus Broad-spectrum Neutralizing Antibody Nasal Spray in Health People
Condition:   COVID-19 Intervention:   Drug: SA55 nasal spray Sponsor:   Sinovac Life Sciences Co., Ltd. Recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

Mental health among UK secondary pupils worsened sharply in pandemic, study shows
First comparative research of its kind finds those with lots of social interaction and supportive family coped betterSecondary school pupils in the UK experienced significantly higher rates of depression, social, emotional and behavioural difficulties, and overall worse mental wellbeing during the Covid pandemic, research shows.Cases of depression among secondary school pupils aged 11 to 13 rose by 8.5% during the pandemic compared with a 0.3% increase for the same cohort prior to Covid, according to a comparative study by researchers at the University of Oxford ’s psychiatry department.Continue reading...
Source: Guardian Unlimited Science - September 21, 2023 Category: Science Authors: Rachel Hall Tags: Young people Mental health Coronavirus UK news Society Medical research Depression University of Oxford Education Schools Children Source Type: news

Biden announces $600m for more free Covid-19 tests in anticipation of surge
The Biden administration announced Wednesday that it is providing $600m in funding to produce new, at-home Covid-19 tests and is restarting a website allowing Americans to again order up to four free tests per household – aiming to prevent possible shortages during a rise in coronavirus cases that…#hhs #usps #maryland #oconnell #xavierbecerra #covid19rapid
Source: Reuters: Health - September 21, 2023 Category: Consumer Health News Source Type: news

The impact of COVID-19 infection before the vaccination era on the hospitalized patients requiring hemodialysis: a single-center retrospective cohort
Ren Fail. 2023;45(2):2251593. doi: 10.1080/0886022X.2023.2251593. Epub 2023 Sep 21.ABSTRACTDue to effective vaccinations, the COVID-19 (coronavirus disease 2019) infection that caused the pandemic has a milder clinical course. We aimed to assess the mortality of hospitalized COVID-19 patients before the vaccination era. We investigated the mortality in those patients between 1 October 2020 and 31 May 2021 who received hemodialysis treatment [patients with previously normal renal function (nCKD), patients with chronic kidney disease previously not requiring hemodialysis (CKDnonHD), chronic kidney disease (CKD), and patients...
Source: Renal Failure - September 21, 2023 Category: Urology & Nephrology Authors: Ákos Géza Pethő P éter Kevei M árk Juha Ágnes Kóczy N óra Ledó Andr ás Tislér Istv án Takács Ádám G Tabák Source Type: research

Effects of pulmonary rehabilitation in survivors of severe acute respiratory syndrome coronavirus 2. Role of vaccination
Monaldi Arch Chest Dis. 2023 Sep 18. doi: 10.4081/monaldi.2023.2738. Online ahead of print.ABSTRACTSurvivors of severe COVID-19 requiring hospital admission may suffer from short- and long-term sequelae, including disability and reduced physical performance. Vaccination and pulmonary rehabilitation (PR) are effective tools against COVID-19 effects. While the beneficial effect of each of these treatments is known, there are no data about their combined effect. In people admitted to PR hospitals after severe COVID-19 disease, we retrospectively analyzed whether PR outcome might be influenced by vaccination status. Ninety-six...
Source: Monaldi Archives for Chest Disease - September 21, 2023 Category: Respiratory Medicine Authors: Matteo Vigna Piero Ceriana Mara Santomassimo Michele Vitacca Mauro Maniscalco Nicolino Ambrosino Source Type: research

Urinary stones complicated with novel coronavirus pneumonia after lung cancer surgery
Panminerva Med. 2023 Sep 21. doi: 10.23736/S0031-0808.23.04938-8. Online ahead of print.NO ABSTRACTPMID:37733011 | DOI:10.23736/S0031-0808.23.04938-8
Source: Panminerva Medica - September 21, 2023 Category: General Medicine Authors: Xiaojuan Li Yanping Cao Pengbo Yin Hongxu Zhang Source Type: research

Paxlovid as a potential treatment for long COVID
Expert Opin Pharmacother. 2023 Sep 21. doi: 10.1080/14656566.2023.2262387. Online ahead of print.ABSTRACTINTRODUCTION: On 31 July 2023, the United States Department of Health and Human Services announced the formation of the Office of Long COVID Research and Practice and the United States National Institutes of Health opened enrollment for RECOVER-Vital, a randomized study to evaluate new treatment options for long Coronavirus (long COVID).AREAS COVERED: The RECOVER Initiative is a $1.15 billion research platform intended to describe, categorize, treat, and prevent long-term symptoms following infection by Severe Acute Res...
Source: Expert Opinion on Pharmacotherapy - September 21, 2023 Category: Drugs & Pharmacology Authors: Matthew W McCarthy Source Type: research

Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Arch Med Sci. 2021 Oct 15;19(5):1410-1420. doi: 10.5114/aoms/142103. eCollection 2023.ABSTRACTCoronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), declared a global pandemic by the World Health Organization (WHO). The three key principles in management of the COVID-19 pandemic are prevention, early detection and targeted treatment. Vaccine-based prevention together with early detection has already proven its efficacy in controlling the pandemic. Early detection of infected patients could substantially accelerate the implementation of treatment,...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Aleksandra Skwarek Aleksandra G ąsecka Mi łosz J Jaguszewski Łukasz Szarpak Tomasz Dzieci ątkowski Krzysztof J Filipiak Source Type: research

Reduction of lymphocyte count at early stage elevates severity and death risk of COVID-19 patients: a hospital-based case-cohort study
CONCLUSIONS: Older COVID-19 patients are more susceptible to lymphopenia. Multiple organ injuries were more serious in COVID-19 patients with lymphopenia. Lymphopenia at an early stage aggravates the severity and elevates the death risk of COVID-19 patients.PMID:37732034 | PMC:PMC10507779 | DOI:10.5114/aoms.2020.99006
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Jun Fei Lin Fu Ying Li Hui-Xian Xiang Ying Xiang Meng-Die Li Fang-Fang Liu De-Xiang Xu Hui Zhao Source Type: research

Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Arch Med Sci. 2021 Apr 23;19(5):1327-1359. doi: 10.5114/aoms/135703. eCollection 2023.ABSTRACTCOVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system. COVID-19 (coronavirus) and other enveloped viruses including severe acute respiratory syndrome (SARS-CoV-1 of 2002-2003) and Middle East respiratory syndrome (MERS; 2012-ongoing) and hepatitis B and C (HBV and HCV) can be inactivated by AA, γ-linolenic acid (GLA, dihomo-GLA (DGLA), eicosapentaenoic ...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Undurti N Das Source Type: research