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Total 230 results found since Jan 2013.

Diagnostic and treatment dilemma during the coronavirus disease 2019 pandemic: a primary pulmonary lymphoma presenting as a cavitary mass in a patient with coronavirus disease 2019: a case report
ConclusionA careful multidisciplinary strategy is required to expeditiously diagnose and treat aggressive cancers of the respiratory tract in patients acutely infected with severe acute respiratory syndrome coronavirus-2 while observing practices to prevent healthcare worker infection during the ongoing coronavirus disease 2019 pandemic.
Source: Journal of Medical Case Reports - January 13, 2023 Category: General Medicine Source Type: research

Increased Incidence of Ventilator-Acquired Pneumonia in Coronavirus Disease 2019 Patients: A Multicentric Cohort Study*
OBJECTIVES: Little is known about the epidemiology of ventilator-acquired pneumonia among coronavirus disease 2019 patients such as incidence or etiological agents. Some studies suggest a higher risk of ventilator-associated pneumonia in this specific population. DESIGN: Cohort exposed/nonexposed study among the REA-REZO surveillance network. SETTING: Multicentric; ICUs in France. PATIENTS: The coronavirus disease 2019 patients at admission were matched on the age, sex, center of inclusion, presence of antimicrobial therapy at admission, patient provenance, time from ICU admission to mechanical ven...
Source: Critical Care Medicine - February 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

The practice of empiric antibiotic therapy in patients with coronavirus disease 2019 (COVID-19)
Conclusion: The results of our study indicate a high frequency of inappropriate prescription of antibiotics in the detection of COVID-19 and a high readiness of doctors to prescribe its for the treatment of mild viral infection.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Fesenko, O. Tags: Respiratory infections and bronchiectasis Source Type: research

Report on the Epidemiological Features of Coronavirus Disease 2019 (COVID-19) Outbreak in the Republic of Korea from January 19 to March 2, 2020.
This report summarizes the epidemiologic features and the snapshots of the outbreak in the Republic of Korea from January 19 and March 2, 2020. PMID: 32174069 [PubMed - in process]
Source: Journal of Korean Medical Science - March 18, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Heart failure with preserved ejection fraction in coronavirus disease 2019 patients: the promising role of diuretic therapy in critically ill patients
We describe a 46‐year‐old man with a history of mild hypertension who presented to the emergency department with fever, cough, and myalgia for 2 days. The patient was tested positive for SARS‐CoV‐2. He was admitted and started on a combinatio n of antiviral and antimicrobial therapy. He developed respiratory distress 2 days later, and O2 saturation declined. Blood tests showed an increased N ‐terminal pro‐B type natriuretic peptide (NT‐proBNP) level, and echocardiography showed normal left ventricular ejection fraction and E/e′ ratio of 16. Computed tomography scan showed interstitial pulmonary oedema and...
Source: ESC Heart Failure - January 14, 2021 Category: Cardiology Authors: Mitra Chitsazan, Ahmad Amin, Mandana Chitsazan, Naghmeh Ziaie, Parviz Amri Maleh, Hamidreza Pouraliakbar, Stephan Von Haehling Tags: Case Report Source Type: research

Molecular detection of bovine coronavirus in a diarrhea outbreak in pasture-feeding Nellore steers in southern Brazil
This study describes the molecular detection of BCoV in a diarrhea outbreak in beef cattle steers (Nellore) raised on pasture in Parana, southern Brazil. During the outbreak, the farm had about 600 fattening steers. Watery and bloody diarrhea unresponsive to systemic broad-spectrum antibiotic therapy reveals a morbidity rate of approximately 15 %. The BCoV N gene was identified in 42.9 % (6/14) of the diarrheic fecal samples evaluated by semi-nested polymerase chain reaction (SN-PCR) technique. Other enteric microorganisms occasionally identified in adult cattle and evaluated in this study such as bovine groups A, B, and...
Source: Tropical Animal Health and Production - December 28, 2015 Category: Veterinary Research Source Type: research

Personalized ß-lactam dosing in patients with coronavirus disease 2019 (COVID-19) and pneumonia: A retrospective analysis on pharmacokinetics and pharmacokinetic target attainment
Pathophysiological changes are important risk factors for critically ill patients with pneumonia manifesting sub-therapeutic antibiotic exposures during empirical treatment. The effect of coronavirus disease 2019 (COVID-19) on antibiotic dosing requirements is uncertain. We aimed to determine the effect of COVID-19 on ß-lactam pharmacokinetics (PK) and PK target attainment in critically ill patients with a personalized dosing strategy. Retrospective, single-center analysis of COVID-19 ± critically ill patients with pneumonia (community-acquired pneumonia or hospital-acquired pneumonia) who received continuous infusi...
Source: Medicine - June 4, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Early viral versus late antibiotic-associated diarrhea in novel coronavirus infection
This study aimed to compare these types of diarrhea. We included patients with COVID-19 in a cohort study and excluded patients with chronic diarrhea, laxative use, and those who died during the first day of hospitalization. There were 89 (9.3%), 161 (16.7%), and 731 (75.7%) patients with early viral, late antibiotic-associated, and without diarrhea, respectively. Late diarrhea lasted longer (6 [4–10] vs 5 [3–7] days, P 0.6 × 109 cells/L predicted the development of late diarrhea in the coming days (sensitivity 82.0%, specificity 70.8%, area under the curve = 0.791 [0.710–0.872]). Diarrhea in CO...
Source: Medicine - October 15, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Methicillin-resistant Staphylococcus aureus lung infection in coronavirus disease 2019: how common?
Purpose of review Some patients with coronavirus disease 2019 (COVID-19) may develop pulmonary bacterial coinfection or superinfection, that could unfavorably impact their prognosis. Recent findings The exact burden of methicillin-resistant Staphylococcus aureus (MRSA) lung infection in peculiar populations such as patients with COVID-19 remains somewhat elusive, possibly because of wide heterogeneity in methods and endpoints across studies. Summary There was important heterogeneity in the retrieved literature on the epidemiology of MRSA lung infection in patients with COVID-19, both when considering all ...
Source: Current Opinion in Infectious Diseases - March 10, 2022 Category: Infectious Diseases Tags: RESPIRATORY INFECTIONS: Edited by Michael S. Niederman Source Type: research

Clinical Impact of Empirical Antibiotic Therapy in Patients With Coronavirus Disease 2019 Requiring Oxygen Therapy
J Korean Med Sci. 2022 Jul 25;37(29):e238. doi: 10.3346/jkms.2022.37.e238.ABSTRACTDespite the low prevalence of secondary bacterial infection in coronavirus disease 2019 (COVID-19) patients, most of them were administered antibiotic therapy empirically. However, the prognostic impact of empirical antibiotic therapy has not been evaluated. We conducted retrospective propensity score-matched case-control study of 233 COVID-19 patients with moderate to severe illnesses who required oxygen therapy and evaluated whether empirical antibiotic therapy could improve clinical outcomes. Empirical antibiotic therapy did not improve cl...
Source: Journal of Korean Medical Science - July 26, 2022 Category: Biomedical Science Authors: Do Hyeon Park Chan Mi Lee Euijin Chang Chang Kyung Kang Wan Beom Park Nam Joong Kim Pyoeng Gyun Choe Myoung-Don Oh Source Type: research