Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | PMC:PMC8691146 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | PMC:PMC8691146 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | PMC:PMC8691146 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats
CONCLUSION: Ergosteroside combined risedronate can patently ameliorate the healing effect of fracture in rats.PMID:34932671 | PMC:PMC8691146 | DOI:10.1590/ACB361107 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 21, 2021 Category: Surgery Authors: Xiaofeng Xu Wenyu Hui Nian Liu Yong Zhang Source Type: research

The Impact of Continuous Passive Motion on Heterotopic Ossification Maturation
Heterotopic ossification is the formation of pathological bone in soft tissues. It is postulated that continuous passive motion is a helpful adjuvant in the halt of the heterotopic ossification progression and the maintenance or increase of the joint mobility. The purpose of this clinical case study is to present the effectiveness of continuous passive motion. A 46-yr-old male patient experiencing right hemiparesis arrived in our rehabilitation department with limitation on passive flexion of the right hip. On x-ray of the pelvis, immature heterotopic bone formation was found. To halt this ongoing process of heterotopic bo...
Source: American Journal of Physical Medicine and Rehabilitation - November 26, 2021 Category: Rehabilitation Tags: Case Reports Source Type: research

Osteoporosis treatment with risedronate: a population pharmacokinetic model for the description of its absorption and low plasma levels
ConclusionThe absorption and disposition kinetics of risedronate were successfully characterized. Simulations revealed the high discrepancy in the concentration levels observed after different dosage regimens, implying the safety profile of risedronate. In virtual patients with renal impairment, the blood levels of risedronate are increased, but not in an extent requiring dose adaptation. (Source: Osteoporosis International)
Source: Osteoporosis International - November 1, 2021 Category: Orthopaedics Source Type: research

Risedronate use to attenuate bone loss following sleeve gastrectomy: Results from a pilot randomized controlled trial
SummaryThe purpose of this study was to explore the efficacy of 150 mg once monthly oral risedronate use in the prevention of sleeve gastrectomy (SG) associated bone loss. Twenty-four SG patients (56 ± 7 years, 83% female, 21% black) were randomized to risedronate or placebo for 6 months, with an optional 12-month assessment. Outcome measures included 6 (n = 21) and 12 (n = 14) month change in dual energy x-ray absorptiometry-acquired regional areal bone mineral density (aBMD). Six-month treatment effect estimates [mean (95% CI)] revealed significant between group aBMD differences at the femoral neck [risedronate: +0.013 ...
Source: Clinical Obesity - September 27, 2021 Category: Eating Disorders & Weight Management Authors: Kristen M. Beavers, Daniel P. Beavers, Adolfo Z. Fernandez, Katelyn A. Greene, Ashlyn A. Swafford, Ashley A. Weaver, Sarah J. Wherry, Jamy D. Ard Tags: Original Research Article Source Type: research

Investigation on Potential of Chitosan Nanoparticles for Oral Bioavailability Enhancement of Risedronate Sodium
In conclusion, developed RS-loaded chitosan nanoparticles seem to be a promising approach to increase oral bioavailability and can avoid upper GI tract side effects.PMID:34535843 | DOI:10.1208/s12249-021-02090-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - September 18, 2021 Category: Drugs & Pharmacology Authors: Nikhil Suthar Jagruti Desai Hetal Paresh Thakkar Source Type: research