IJERPH, Vol. 18, Pages 12441: Application of Inspiratory Muscle Training to Improve Physical Tolerance in Older Patients with Ischemic Heart Failure
echura Regardless of the management regime for heart failure (HF), there is strong evidence supporting the early implementation of exercise-based cardiac rehabilitation (CR). Respiratory therapy is considered to be an integral part of such secondary prevention protocols. The aim of the study was to evaluate the effect of inspiratory muscle training (IMT) on exercise tolerance and the functional parameters of the respiratory system in patients with heart failure involved in cardiac rehabilitation. The study included 90 patients with HF who took part in the second-stage 8-week cycle of cardiac rehabilitation (CR). They w...
Source: International Journal of Environmental Research and Public Health - November 26, 2021 Category: Environmental Health Authors: Monika Piotrowska Paulina Okrzymowska Wojciech Kucharski Krystyna Ro żek-Piechura Tags: Article Source Type: research

Eosinopenia in COPD patients with severe acute respiratory virus 2 (Sars-CoV-2) infection as a potential fatal outcome predictor
Eosinophils contribute to innate antiviral immunity of the lung and eosinophilic blood count can be used as an early, effective and relevant biomarker predicting high disease severity in COPD patients with Sars-CoV-2 infection. Aim was to investigate the diagnostic and prognostic value of eosinopenia in Covid-19 positive COPD patients. Retrospective pilot study based on medical record review was performed on patients admitted for hospital treatment from the start of pandemic in March 2020 till end of January 2021. All patients had a positive PCR test at the moment of admission and COPD diagnose was confirmed from the medic...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Paluero, J.-E., Tokhi, L., Roglic, M., Labor, M. Tags: Monitoring airway disease Source Type: research

Early intervention with non-invasive respiratory therapies in mild acute respiratory distress syndrome secondary to COVID-19
Conclusion: Early intervention with NIRT did not reduce orotracheal intubations or deaths in a group of COVID-19 patients with mild ARDS. Characteristic All patients (N=42) Cases (N=14) Controls (N=28) p-valueAge, years (SD)60.9 (11.7)60.4 (11.9)61.2 (11.7)0.84Males, %28 (66.7)9 (64.3)19 (67.9)1.00Body mass index, kg/m2 (SD)29.5 (5.6)28.7 (5.7)30.0 (5.6)0.51Charlson index (SD)1.9 (1.6)1.9 (1.3)1.9 (1.5)0.49SpO2/FiO2 pre-NIRT (SD)269.1 (18.4)272.3 (20.0)267.5 (17.7)0.43C reactive protein pre-NIRT (SD)12.9 (8.4)12.1 (8.9)13.4 (8.2)0.65SOFA score pre-NIRT (SD)3.1 (1.3)2.8 (0.9)3.2 (1.4)0.32 (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Suarez Escudero, S., Lopez-Padilla, D., Teran Tinedo, J. R., Parra Leon, V., Lopez Martin, S., Caballero Segura, F., Castro Riera, C., Cerezo Lajas, A., Ojeda Castillejo, E., Recio Moreno, B., Puente Maestu, L. Tags: Noninvasive ventilatory support Source Type: research

First and second waves results of COVID-19 patients treated with non-invasive respiratory therapies outside the ICU: unicentric, observational study
Conclusions: Sixty-day mortality in COVID-19 patients treated with NIRT was of almost 38%, where age, comorbidities, SOFA score and lactate dehydrogenase associated with mortality. Multivariate analysisORCI95%p-valueAge1.071.04 – 1.11<0.01Charlson comorbidity index1.231.02 – 1.480.03Lactate dehydrogenase1.021.01 – 1.050.04SOFA score1.631.24 – 2.13<0.01 (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Parra Leon, V., Lopez-Padilla, D., Teran Tinedo, J. R., Suarez Escudero, S., Lopez Martin, S., Ojeda Castillejo, E., Caballero Segura, F., Recio Moreno, B., Castro Riera, C., Puente Maestu, L. Tags: Noninvasive ventilatory support Source Type: research