High Risk Surgical Patients Have Lower Mortality Rates at Major Teaching Hospitals
I firmly believe that it's important to get oneself to a major teaching hospital if you fall into the category of a high risk, general surgery patient. A recent article put some numbers to this advice (see:High risk patients have lower mortality rates at major teaching hospitals). Below is an excerpt from the article:New research published in the Annals of Surgery shows that high-risk general surgery patients have greater survival rates at major teaching hospitals than at non-teaching hospitals....The 30-day mortality rate for these high-risk patients was 15.9% at major teaching hospitals, compared with 18.2% at ...
Source: Lab Soft News - October 30, 2019 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Cost of Healthcare Healthcare Delivery Hospital Financial Medical Research Population Health Public Health Quality of Care Source Type: blogs

Using FibroScan in The Clinic: Interview with Dr. Stephen A. Harrison
EchoSens creates non-invasive liver diagnosis medical devices. The company’s line of products, called FibroScan, work by measuring the speed of ultrasound waves as they move through liver tissue. This measurement can tell us about the state of the liver. For example, ultrasound waves move faster through fibrotic/scarred livers. EchoSens recently appointed Dominique Legros as their new global CEO, and we recently spoke about his plans for growth in a Medgadget exclusive.  To learn more about how a clinician would use the FibroScan, we spoke with Dr. Stephen A. Harrison, Medical Director of Pinnacle Clinical Re...
Source: Medgadget - September 30, 2019 Category: Medical Devices Authors: Ben Ouyang Tags: Diagnostics Exclusive GI Medicine Source Type: blogs

Fight Aging! Newsletter, September 23rd 2019
Discussion of Developmental Effects on Aging Microtubule Function and Longevity in Nematodes Quantifying the Correlation Between Poverty and Faster Pace of Aging Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019 https://www.fightaging.org/archives/2019/09/matthew-oconnor-presenting-on-underdog-pharmaceuticals-at-undoing-aging-2019/ Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atheroscle...
Source: Fight Aging! - September 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019
Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atherosclerosis and other conditions. Oxidized cholesterols, and largely 7-ketocholesterol, are the primary cause of dysfunction in the macrophage cells normally responsible for preventing the build up of fatty plaques in blood vessel walls. That dysfunction is the cause of atherosclerosis, and the fact that the presence of oxidized cholesterols increases with age is one of the reasons why ath...
Source: Fight Aging! - September 16, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Fight Aging! Newsletter, September 16th 2019
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - September 15, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

LEAF Interviews David Sinclair
David Sinclair recently published a new book to assist in publicizing his present research directions, companies, and thinking on aging, and is here interviewed by the Life Extension Advocacy Foundation (LEAF) volunteers. The work presently underway includes supplements to increase levels of NAD+ in mitochondria and, separately, partial reprogramming of cells in a living individual in order to gain some of the effects of full reprogramming, particularly restoration of mitochondrial function. Fully reprogramming cells into induced pluripotent stem cells has been shown to clear out dysfunctional mitochondria and reset epigen...
Source: Fight Aging! - September 12, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Much Is Life Worth?
Multivitamins, drugs, gene therapies, human skin, heart, eyeballs, kidneys, entire dead bodies – everything comes with a price tag. Putting aside the moral questions of why and how come that the capitalist market priced even our body parts and health, we asked the question of how much is life worth: what is the maximum that you would/should pay for a life-saving drug? How high is too high a cost if a drug can save 200-300 babies a year from debilitating illness or death? And ultimately, does the pricing of new technologies, especially gene therapies, enable to fulfill their promise? There’s a price for everything: ...
Source: The Medical Futurist - August 31, 2019 Category: Information Technology Authors: nora Tags: Bioethics Biotechnology Future of Pharma Genomics cost daraprim drug drug price Gene gene therapy genetics insulin life medication pricing policy rare disease rare disorder Source Type: blogs

Commentators and Journalists Weigh In On Digital Health And Related Privacy, Safety And Security Matters. Lots Of Interesting Perspectives - August 27, 2019.
-----This weekly blog is to explore the larger issues around Digital Health, data security, data privacy and related matters.I will also try to highlight ADHA Propaganda when I come upon it.Just so we keep count, the latest Notes from the ADHA Board are dated 6 December, 2018! Secrecy unconstrained! This is really the behavior of a federal public agency gone rogue!-----https://gardn.org.au/news/my-health-record-presentation/My Health Record Presentation20, Aug 2019 ADHA PropagandaGenetic and Rare Disease Network and WA Primary Health Alliance (WAPHA) collaborated in June to bring you an information session to learn about t...
Source: Australian Health Information Technology - August 26, 2019 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Why Don ’t Digital Health Investors Finance Solutions To Tough Medical Issues?
Why did activity trackers flood the digital health market, while there’s barely a company dealing with menopause, arthritis, or rare diseases? How do digital health investors decide when it comes to funding a new project, and what are the specific factors to take into account in relation to the healthcare market? We looked around what could scare off financiers from funding tough medical issues, and have a suggestion on how to bring forward solutions for marginalized health problems. Read on. Investment in digital health for everyone? Investment in healthcare, especially in the digital health market, is growing ste...
Source: The Medical Futurist - August 3, 2019 Category: Information Technology Authors: nora Tags: Business Future of Medicine companies company digital digital health digital health startups finance funding Healthcare investment technology Source Type: blogs

Why Don ’t Digital Health Investors Finance Tough Medical Issues?
Why did activity trackers flood the digital health market, while there’s barely a company dealing with menopause, arthritis, or rare diseases? How do digital health investors decide when it comes to funding a new project, and what are the specific factors to take into account in relation to the healthcare market? We looked around what could scare off financiers from funding tough medical issues, and have a suggestion on how to bring forward solutions for marginalized health problems. Read on. Investment in digital health for everyone? Investment in healthcare, especially in the digital health market, is growing ste...
Source: The Medical Futurist - August 3, 2019 Category: Information Technology Authors: nora Tags: Business Future of Medicine companies company digital digital health digital health startups finance funding Healthcare investment technology Source Type: blogs

Fixing the present, building for the future: newborn screening for rare conditions
This report contains recommendations to adapt decision making to fit rare diseases, to embrace the potential of screening as a rare disease identification system, and to take advantage of developments in technology.Report and charterGenetic Alliance UK - news (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - July 24, 2019 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities New technologies Source Type: blogs

Genome sequencing and the NHS: the views of rare disease patients and carers
Genetic Alliance UK - Genomics England commissioned Genetic Alliance UK to seek the views of patients and carers around the introduction of whole genome sequencing (WGS) into the NHS. They also wanted to hear about people ’s experiences of taking part in the 100,000 Genomes Project. This information will be used by Genomics England to inform the launch of mainstream WGS, as part of the new Genomic Medicine Service.ReportPress release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - July 22, 2019 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Source Type: blogs

New Organization Forms to Confront the Epidemic of Popcorn Lung
Prompted by the statements of anti-tobacco groups throughout the country claiming that vaping causes popcorn lung, a new organization was launched this past Thursday to confront this new and alarming epidemic among young people. The organization is called the American Popcorn Lung Association (APLA) and it has aTwitter feed (@LungPopcorn)." Popcorn lung " is a serious, progressive lung disease that is technically known as bronchiolitis obliterans. The disease results in obstruction of the smallest airways in the lung. The disease is irreversible and can be fatal. A lung transplant is the only definitive treatment. The most...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - July 15, 2019 Category: Addiction Source Type: blogs

Multi-Organ Lab-on-a-Chip for Cancer Drug Testing
Researchers at Hesperos, Inc., a biotech firm based in Florida, have collaborated with Roche and the University of Central Florida to develop a multi-organ lab-on-a-chip system for drug testing. The device includes human organ-derived tissue constructs that allow for the efficacy and side-effects of anti-cancer drugs in various organs to be tested in a way that does not involve laboratory animals. The technique is another step for lab-on-a-chip devices in making preclinical testing easier, less expensive, and more humane. Lab-on-a-chip devices for drug testing are an active area of research, with numerous devices being ...
Source: Medgadget - June 20, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Source Type: blogs

Healthcare In Estonia: Where Grandmas Go For Genetic Data
Imagine a country where citizens will have their genetic profiles integrated into the digital health system with individual risk scores and pharmacogenomic information, so when they go to the doctor, they will get fully personalized, genetic risk-based diagnosis, medication, and preventive measures. That’s where healthcare in Estonia will arrive soon. They started to build their digital health system 20 years ago, and within the next years, the Baltic country will start to reap the benefits of a transparent, blockchain-based, digital health system hooked on genetic data. The first fully digitized republic certainly sets ...
Source: The Medical Futurist - May 16, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Healthcare Policy analysis digital digital democracy digital health digital health strategy digital health system digital healthcare Estonia genetics genomics personalized Personalized medicine pharmacogenomi Source Type: blogs