Does this T wave pattern mean anything?
Written by Michael Doyle DO and Timothy Palmieri MD. Edited by Bracey, Meyers, Grauer, and SmithA 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiac arrest with return of spontaneous circulation. The described rhythm was an irregular, wide complex rhythm. By EMS report, open pill bottles were found nearby at the scene, including quetiapine, fluoxetine, hydroxyzine, and gabapentin. She was successfully revived after several rounds of ACLS including defibrillation and amiodarone.On arrival to the ED the patient was intubated with normal vi...
Source: Dr. Smith's ECG Blog - October 23, 2023 Category: Cardiology Authors: Bracey Source Type: blogs

Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reactive Astrocytes in Neurodegenerative Conditions
Chronic, unresolved inflammation in brain tissue is a feature of age-related neurodegenerative conditions, and may even be the most important mechanism in these very complex conditions. The supporting cells of the brain, primarily microglia and astrocytes, become more active and inflammatory in later life. This overlaps with a rising count of senescent cells in these populations. Senescent cells produce an outsized contribution to inflammatory signaling, belying their relatively small numbers compared to non-senescent cells. Active microglia and astrocytes are largely not senescent, however. They are reacting to inflammato...
Source: Fight Aging! - March 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Prozac And Zoloft Worsen Anxiety: SSRI Side-Effect
SSRI antidepressants such as Prozac and Zoloft can increase anxiety in the first few weeks. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 23, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Antidepressants Source Type: blogs

Mapping ‘psychedelic trips’ in the brain to better direct their therapeutic effects
This article was originally published on The Conversation. To learn more: Why MDMA-assisted psychotherapy may become an FDA-approved treatment for PTSD within 2 years Next: Psychedelic-assisted psychotherapy? The post Mapping ‘psychedelic trips’ in the brain to better direct their therapeutic effects appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - April 4, 2022 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health academic research anxiety artificial intelligence brain regions cognitive-flexibility depression psychedelics psychiatric conditions psychotropic drugs therapeutic treat psychiatric conditions Source Type: blogs

Xylological Delusions of Being a Tree
The mythology surroundingreverse inter-metamorphosis, a delusional syndrome that involves transformation into a beast, has frightened and fascinated for hundreds of years. A special instance of reverse inter-metamorphosis isclinical lycanthropy, the delusion that one has been transformed into a wolf (or another animal). A recent review identified 43 cases in the literature between 1852 and today (Guessoum et al., 2021). Psychotic depression and schizophrenia were the most common co-existing psychiatric diagnoses in these individuals.The article advocates a cultural and person-centered approach to treatment, as did many of ...
Source: The Neurocritic - October 31, 2021 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

We Shouldn ’t Tolerate Sloppy Allergy Lists
By HANS DUVEFELT The medication and allergy lists seem like they would be the most important parts of a health record to keep current and accurate. But we all see errors too often. I think it shouldn’t be possible to enter an allergy without describing the reaction. Because without that information the list becomes completely useless. The other day I saw a patient who needed an urgent CT angiogram. The allergy list said “All Contrast Materials”, which isn’t even “structured data entry”, and thus not recognized by the computer if my EMR (Me again, Greenway!) would have been clever enough to check for al...
Source: The Health Care Blog - October 4, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Primary Care Hans Duvefelt Source Type: blogs

Screening for Depression: Then What?
By HANS DUVEFELT Primary Care is now mandated to screen for depression, among a growing host of other conditions. That makes intuitive sense to a lot of people. But the actual outcomes data for this are sketchy. “Don’t order a test if the results won’t change the outcome” was often drilled into my cohort of medical students. Even the US Public Health Service Taskforce on Prevention admits that depression screening needs to take into consideration whether there are available resources for treatment. They, in their recommendation, refer to local availability. I am thinking we need to consider the availability i...
Source: The Health Care Blog - May 11, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care depression depression screening Hans Duvefelt Source Type: blogs

The Art of Prescribing (Or Not)
By HANS DUVEFELT I have learned a few things about prescribing medications during my 42 years as a physician. Some are old lessons, and some are more recent. I thought I’d share some random examples. First: I don’t like to have to use medications, but when they seem necessary, I choose, present and prescribe them with great care. CHOOSING MEDICATIONS Medications are like people. They have personalities. With so many choices for any given diagnosis or symptom, I consider their mechanism of action, possible beneficial additional effects and their risk of unwanted side effects when selecting which one to presc...
Source: The Health Care Blog - February 1, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Hans Duvefelt Source Type: blogs

Sarah ’ s Wheat Belly health and life transformation
  Sarah’s story reminds us how the simple matter of diet can shape our lives for decades, affecting energy, body weight, emotional health–just about every aspect of our physical and social lives before we finally stumble on the right answers. After many years of struggling with poor health, relying on prescription medications that never addressed underlying causes, it therefore came as a surprise to Sarah that she could indeed achieve magnificent health without the drugs by simply following the diet programmed into human genetic code and supplementing nutrients that are deficient in modern life.   ...
Source: Wheat Belly Blog - January 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free Inflammation joint pain wheat belly Source Type: blogs

Ranolazine – Class Id
Ranolazine, originally introduced as an antianginal agent for the treatment of chronic stable angina, is now being recognized as an antiarrhythmic agent as well. It has been included in the class Id of the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. Class Id is by virtue of its inhibition of late Na+ current (INaL). It has been included among the drugs for treatment of ventricular arrhythmias in the 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death [2]. Ranolazine reduces early after depolarization (EAD) induced triggered activ...
Source: Cardiophile MD - October 15, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: ECG / Electrophysiology Source Type: blogs

Children, teens, and the safety of psychotropic medicines
Medicines prescribed for attention deficit/hyperactivity disorder (ADHD), depression, anxiety, and other mood disorders — known as psychotropic drugs — have largely been studied in adults. This concerns many parents whose children take these drugs regularly. Studies have most often looked at the effectiveness of these medicines in teens and children. Now a recent systematic review of multiple studies done in children and adolescents offers new guidance on safety for commonly used medicines. What did the study look at? The aim of this study was to comprehensively synthesize current evidence on the safety of four major c...
Source: Harvard Health Blog - August 6, 2020 Category: Consumer Health News Authors: Hyun Jung Kim, MD Tags: Adolescent health Anxiety and Depression Behavioral Health Children's Health Mental Health Parenting Source Type: blogs

Top 25 Psychiatric Medications for 2018
Psychiatric medications are an important part of treatment for many people with mental disorders, such as depression, bipolar disorder, ADHD, schizophrenia, anxiety, and others. They play an important role in helping to alleviate the most serious symptoms, allowing people to better focus on their lives and on other treatment types, such as psychotherapy. Psychiatric medications are an important part of many people’s treatment plans for obtaining the most effective treatment for a mental health concern or mental illness. It’s good to know what drugs are being prescribed most often for mental disorders in the U.S...
Source: World of Psychology - December 15, 2019 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: General Medications Psychiatry psychiatric meds psychiatric prescriptions Source Type: blogs

Inside Schizophrenia: Childhood Schizophrenia
 In this episode of Inside Schizophrenia, our hosts tackle the topic of early onset – or childhood – schizophrenia. Host Rachel Star discusses her personal experiences with schizophrenia symptoms as an adolescent and Dr. Joseph Gonzalez-Heydrich from Harvard Medical School discusses some of the latest research. Listen in now! About Our Guest Joseph Gonzalez-Heydrich, MD is Director of the Developmental Neuropsychiatry Clinic at Boston Children’s Hospital and an Associate Professor of Psychiatry at the Harvard Medical School. He did his undergraduate and medical school at Johns Hopkins, his residency training at U...
Source: World of Psychology - July 17, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Disorders Inside Schizophrenia Psychiatry Source Type: blogs

The Paracetamol Papers
I have secretly obtained a large cache of files from Johnson& Johnson, makers of TYLENOL ®, the ubiquitous pain relief medication (generic name: acetaminophen in North America,paracetamol elsewhere). The damaging information contained in these documents has been suppressed by the pharmaceutical giant, for reasons that will become obvious in a moment.1After a massive upload of materials to Wikileaks, it can now be revealed that Tylenol not only...eases social rejectionmends a broken heartlessens mortality salience(i.e., fear of death)reduces antisocial behaviortreats chronic anxiety disorder...but along with the good c...
Source: The Neurocritic - April 26, 2019 Category: Neuroscience Authors: The Neurocritic Source Type: blogs