The Complicated Prostate: Cancer Is a Concern but There's More to Consider
Most younger men don’t spend a lot of time considering the health of their prostate. However, around the age of 50, they’ll likely find that their physicians want to check out prostate health both physically and through blood work known as a prostate-specific antigen (PSA) test. The PSA is not a perfect test, but it’s still used to help detect prostate cancer since there aren’t many alternatives. National Prostate Cancer Awareness Month is meant to increase the knowledge about possible prostate problems and make certain that men get checked out regularly. What is the prostate? The prostate is a small organ locat...
Source: Minding Our Elders - September 7, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 01, 2022 Edition-----This week it is all about weather and climate change with floods, heatwaves and droughts in Parkistan, Europe and China. In the US drought is causing all sorts of food supply issues and price rises.In the EU was a seeing all sorts of energy supply problems.In Australia we have a feast of investigations into ScoMo, RoboDebt and so on. Lots to browse!-----Major Issues.-----https://www.afr.com/policy/foreign-affairs/us-alliance-fear-that-dare-not-speak-its-name-20220818-p5bat8US alliance fear that dare not speak its nameUneasiness about divided, inward-looking America fulfilling its security gua...
Source: Australian Health Information Technology - September 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Mining Ultrasound Data to Improve Liver Diagnostics: Interview with Beth Rogozinski, CEO at Oncoustics
Oncoustics, a medtech company based in Ontario, Canada, developed the OnX Liver Assessment Solution, an AI-powered ultrasound-based diagnostic system for liver disease. At present, detecting liver disease is a challenge, potentially involving high-end imaging systems, specialists, and invasive biopsies. These challenges, and the related expense, can limit patient access to such testing for those with strong indications of liver disease. Consequently, in many cases, liver disease may not be detected until it is already quite advanced, limiting the potential for early detection and treatment. There is a clear need for a n...
Source: Medgadget - August 23, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Oncology Radiology liver disease oncoustics Source Type: blogs

Weekly Overseas Health IT Links –20th August 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://www.digitalhealth.net/2022/08/ai-predictive-trial-staffordshire-hn-reduce-ae-admissions/AI predictive trial in Staffordshire reduces A&E admissions by 35%A trial which looked at how existing patient data could be used to predict those most likely to need hospital care has led to a 35% reduction on average in A&E attendances across Staffordshire.Jor...
Source: Australian Health Information Technology - August 20, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, July 11th 2022
In this study we employ a transcriptome-wide and multi-tissue approach to analyze the influence of both LTDR and short-term DR (STDR) at old age on the aging phenotype. We were able to characterize a common transcriptional gene network driving inflammaging in most of the analyzed tissues. This network is characterized by chromatin opening and upregulation in the transcription of innate immune system receptors and by activation of interferon signaling through interferon regulatory factors, inflammatory cytokines, and Stat1-mediated transcription. We also found that both DR interventions ameliorate this inflammaging phenotyp...
Source: Fight Aging! - July 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

6 changes that could lower the risk of developing prostate cancer
After skin cancer, prostate cancer is the most common type of cancer diagnosed in people with a prostate. Some risk factors associated with prostate cancer can’t be mitigated. Those factors include older age, a family history of prostate cancer, and race (Black men have double the risk of developing prostate cancer compared to white men).Read more …6 changes that could lower the risk of developing prostate cancer originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 7, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/miles-j-varn" rel="tag" data-wpel-link="internal" > Miles J. Varn, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs

Cancer Survivors Exhibit a Significantly Higher Risk of Cardiovascular Disease
The dominant cancer therapies of chemotherapy and radiotherapy have not yet been replaced by immunotherapies for more than a handful of cancer types. These classes of therapy produce a significantly increased burden of senescent cells in patients; one of the goals of cancer therapy is to drive cancerous cells into senescence, those that cannot be killed. These additional senescent cells in turn accelerate the progression of degenerative aging. The advent of senolytic therapies to clear senescent cells from aged tissues will make a sizable difference to these patients. More effort should be undertaken today to enable patien...
Source: Fight Aging! - July 4, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How IoT Medical Devices Save and Improve Lives
The following is a guest article by Erik Kling, Interim Head of IoT Americas at Vodafone Business. IoT, or the Internet of Things, has transformed our homes with connected lights and smart appliances. It’s also revolutionized all areas of business, including manufacturing. Sensors connected to the internet can track goods throughout the supply chain — from sourcing materials to delivering completed products to consumers. IoT technology has improved the way we live, but its most profound impact may be in healthcare, where it’s saving lives and improving health. Before IoT revolutionized healthcare, doctors and care pr...
Source: EMR and HIPAA - June 23, 2022 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT IT Infrastructure and Dev Ops AED American College of Cardiology Connected Defibrillators Continuous Glucose Monitors CPAP Dr. Ami Bhatt Elliot Erik Kling Healthcare AI Source Type: blogs

Science Snippet: RNA ’s Remarkable Roles
RNA, though less well known than its cousin DNA, is equally integral to our bodies. RNA molecules are long, usually single-stranded chains of nucleotides. (DNA molecules are also made up of nucleotides but are typically double-stranded.) There are three major types of RNA, which are all involved in protein synthesis: Messenger RNA (mRNA) is complementary to one of the DNA strands of a gene and carries genetic information for protein synthesis to the ribosome—the molecular complex in which proteins are made.Transfer RNA (tRNA) works with mRNA to make sure the right amin...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 18, 2022 Category: Research Authors: Matt Mills Tags: Cells Injury and Illness Cellular Processes RNA Science Snippet Source Type: blogs

Fight Aging! Newsletter, May 16th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 15, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing Mitochondria-Derived Peptides in Aging
Researchers have explored a number of mitochondria-derived peptides as a basis for treatments in the context of aging. These peptides are created from fragments of genes in the mitochondrial DNA, released from the cell, and appear to be involved in a range of mechanisms relevant to declining function in aging. Is it possible to supply such peptides as a therapy in order to produce benefits in an aged metabolism? A number of groups working towards that goal, on the basis of data in animal studies and humans patients. The mechanisms that explain mitochondrial dysfunction in aging and healthspan continue to be studie...
Source: Fight Aging! - May 13, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article. It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs

Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mcl-1 Inhibitors as a Novel Class of Senolytic
Researchers working with prostate cancer cells here show that senescent cancer cells depend upon Mcl-1 to prevent programmed cell death, a novel target with existing drugs that may prove useful as general purpose senolytics, able to clear senescent cells from tissues. Cancers are highly varied, and this would have to be tested against the more usual types of senescent cell present in the aged body. Even if only applicable in the context of some cancers, however, this is still a useful discovery. Cancer survivors have a significantly reduced life expectancy in large part because they suffer a greatly increased burden of cel...
Source: Fight Aging! - April 29, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Prostate cancer, sex drive, male menopause and conversations to have with your doctor
Americans are having less sex than ever before. Should we be worried? Ask your prostate. A 2022 study from the National Survey of Sexual Health and Behavior found that the rate of all types of sexual intercourse have declined from 2009 to 2018. While the authors speculate as to why this may be the caseRead more …Prostate cancer, sex drive, male menopause and conversations to have with your doctor originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 21, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/kevin-charles-king" rel="tag" data-wpel-link="internal" > Kevin Charles King, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs