Evaluation of Psychiatric Symptomatology, Quality of Life, and Caregiver Burden in Mothers and Children with Primary Immunodeficiency
CONCLUSION: Statistically, we found significantly lower psychosocial health summary scores and total scale score levels from the subclass of PedsQL in the patient group than in the control group. According to the views of both children and mothers, we observed that PID children had higher depression and anxiety scores than healthy children. It was also found that the BDI and BAI values in case of mothers in the patient group were significantly higher than those in the control group.PMID:37937495 | DOI:10.15586/aei.v51i6.927 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - November 8, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research

Primary immunodeficiency diseases of adults: a review of pulmonary complication imaging findings
AbstractOur objective in this review is to familiarize radiologists with the spectrum of initial and progressive CT manifestations of pulmonary complications observed in adult patients with primary immunodeficiency diseases, including primary antibody deficiency (PAD), hyper-IgE syndrome (HIES), and chronic granulomatous disease (CGD). In patients with PAD, recurrent pulmonary infections may lead to airway remodeling with bronchial wall-thickening, bronchiectasis, mucus-plugging, mosaic perfusion, and expiratory air-trapping. Interstitial lung disease associates pulmonary lymphoid hyperplasia, granulomatous inflammation, a...
Source: European Radiology - November 8, 2023 Category: Radiology Source Type: research

Estimating the prevalence of immunocompromising conditions and primary immunodeficiency disorders in the Chinese population
To the Editor: (Source: Journal of Infection)
Source: Journal of Infection - November 7, 2023 Category: Infectious Diseases Authors: Tao Chen, Hongni Wang, Hongbo Lin, Jianhua Liu, Chuanxi Fu Tags: Letter to the Editor Source Type: research

Effectiveness of infliximab in common variable immunodeficiency associated with enteropathy
Rev Esp Enferm Dig. 2023 Nov 6. doi: 10.17235/reed.2023.10032/2023. Online ahead of print.ABSTRACTCommon Variable Immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in adults, with non-infectious gastrointestinal involvement present in up to 50% of patients, with the small intestine and colon being the most affected areas. Reports have evaluated the effectiveness of biologic therapy in this scenario. Here, we describe the clinical, endoscopic, and histological findings of a patient who presented a satisfactory response to infliximab.PMID:37929954 | DOI:10.17235/reed.2023.10032/2023 (Source: Rev...
Source: Revista Espanola de Enfermedades Digestivas - November 6, 2023 Category: Gastroenterology Authors: Rodrigo Quera Paulina N úñez Figueroa P ía Zañartu Luis Contreras Source Type: research

Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis
CONCLUSION: The cuproptosis may be a potential pathogenesis of atherosclerosis and CRGs may be promising markers for the diagnosis and molecular subtypes identification of atherosclerosis.PMID:37928399 | PMC:PMC10622704 | DOI:10.1016/j.heliyon.2023.e21158 (Source: Atherosclerosis)
Source: Atherosclerosis - November 6, 2023 Category: Cardiology Authors: Mengxi Wang Liying Cheng Qian Xiang Ziwei Gao Yuhan Ding Haitao Xie Xiaohu Chen Peng Yu Le Shen Source Type: research

Effectiveness of infliximab in common variable immunodeficiency associated with enteropathy
Rev Esp Enferm Dig. 2023 Nov 6. doi: 10.17235/reed.2023.10032/2023. Online ahead of print.ABSTRACTCommon Variable Immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in adults, with non-infectious gastrointestinal involvement present in up to 50% of patients, with the small intestine and colon being the most affected areas. Reports have evaluated the effectiveness of biologic therapy in this scenario. Here, we describe the clinical, endoscopic, and histological findings of a patient who presented a satisfactory response to infliximab.PMID:37929954 | DOI:10.17235/reed.2023.10032/2023 (Source: Rev...
Source: Revista Espanola de Enfermedades Digestivas - November 6, 2023 Category: Gastroenterology Authors: Rodrigo Quera Paulina N úñez Figueroa P ía Zañartu Luis Contreras Source Type: research