Case Report: COVID Associated Pancytopenia Unmasking Previously Undiagnosed Pernicious Anemia
We report a case of a symptomatic 24-year-old active duty male in Hawaii with post-COVID pancytopenia that was found to have previously undiagnosed pernicious anemia and his response to standard treatment.PMID:35405638 | DOI:10.4269/ajtmh.21-1194 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 11, 2022 Category: Infectious Diseases Authors: Javier J Barranco-Trabi Robert Minns Roushon Akter Katherine Park Sean Babb Jennifer Masel Source Type: research

Case Report: COVID Associated Pancytopenia Unmasking Previously Undiagnosed Pernicious Anemia
We report a case of a symptomatic 24-year-old active duty male in Hawaii with post-COVID pancytopenia that was found to have previously undiagnosed pernicious anemia and his response to standard treatment.PMID:35405638 | DOI:10.4269/ajtmh.21-1194 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 11, 2022 Category: Tropical Medicine Authors: Javier J Barranco-Trabi Robert Minns Roushon Akter Katherine Park Sean Babb Jennifer Masel Source Type: research

Elevated IL-19 Serum Levels in Patients With Pernicious Anemia and Autoimmune Gastritis
Pernicious anemia (PA) is a megaloblastic anemia consisting of hematological, gastric and immunological alterations. The immunopathogenesis of PA is sustained by both autoantibodies (e.g. intrinsic factor (IFA) antibodies and anti parietal cell (PCA) antibodies and autoreactive T cells specific for IFA and the parietal cell proton pump ATPase. Iron deficient anemia (IDA) is a microcytic anemia and represents the most common cause of anemia worldwide. Our work aimed to investigate serum levels of several interleukins (IL) of the IL-20 cytokine subfamily in patients with PA, with IDA and in healthy subjects (HC). We compared...
Source: Frontiers in Immunology - April 11, 2022 Category: Allergy & Immunology Source Type: research

Falsely elevated serum vitamin B12 levels in a case of pernicious anemia
(Source: Annals of Hematology)
Source: Annals of Hematology - April 1, 2022 Category: Hematology Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research

Vitamin B12 absorption and malabsorption
Vitam Horm. 2022;119:241-274. doi: 10.1016/bs.vh.2022.01.016. Epub 2022 Mar 1.ABSTRACTVitamin B12 is assimilated and transported by complex mechanisms that involve three transport proteins, intrinsic factor (IF), haptocorrin (HC) and transcobalamin (TC) and their respective membrane receptors. Vitamin deficiency is mainly due to inadequate dietary intake in vegans, and B12 malabsorption is related to digestive diseases. This review explores the physiology of vitamin B12 absorption and the mechanisms and diseases that produce malabsorption. In the stomach, B12 is released from food carrier proteins and binds to HC. The degr...
Source: Vitamins and Hormones - March 26, 2022 Category: Endocrinology Authors: Jean-Louis Gu éant Rosa-Maria Gu éant-Rodriguez David H Alpers Source Type: research