New National Academy of Sciences Members Minisymposium
A mini-symposium featuring NIH's three newest investigators elected to the National Academy of Sciences: Carolina Barillas-Mury (NIAID), Marius Clore (NIDDK), and Shiv Grewal (NCI). Each will speak about their latest research. Barillas-Mury is chief of the Mosquito Immunity and Vector Competence Section in the NIAID Laboratory of Malaria and Vector Research. She investigates the interactions between the mosquito immune system and Plasmodium parasites to understand how they affect malaria transmission. Clore is an NIH Distinguished Investigator in the NIDDK Laboratory of Chemical Physics. His lab is develo...
Source: Videocast - All Events - June 13, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video

Genetic Basis of Protozoan Pathogan Emergence and Disease
Presented by: Michael Grigg, Ph.D. Chief, Molecular Parasitology Section, Laboratory of Parasitic Diseases, NIAID, NIH Category: NIH Director's SeminarsAired date: 03/07/2014 (Source: Videocast - All Events)
Source: Videocast - All Events - March 11, 2014 Category: Journals (General) Tags: Past Events Source Type: video

Genetic Basis of Protozoan Pathogan Emergence and Disease
NIH Director's Seminar Dr. Grigg’s research program investigates the emergence and pathogenesis of prevalent zoonoses that infect a broad spectrum of animal and human hosts. His group is particularly focused on the protozoan parasites Toxoplasma, Leishmania, Giardia, and Cryptosporidium. He performs population and molecular genetic analyses, using both forward and reverse genetics, to identify virulence genes that control pathogenesis and perturb immune system homeostasis in animal models of natural infection. Recent work is exploring the extent to which protozoan parasites utilize their sexual cycles to rapidly produce...
Source: Videocast - All Events - March 4, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video

Discovery of Vaccine and/or Drug Targets in Plasmodium Falciparum using Irradiated Long-Lived Merozoites
Development of a malaria vaccine, as well as, new drugs is crucial for the future control of Plasmodium falciparum, the most severe form of human malaria causing nearly a million deaths each year. Unfortunately, no licensed malaria vaccine is available and development of drug resistant parasites is a continual problem. To provide future opportunities for development, we aimed to identify the phenotypic difference(s) between a novel irradiated P. falciparum long-lived merozoite line and its parental line that displays up to a 20 fold increase in erythrocyte invasion rates, in vitro. Using the tools of systems biology, t...
Source: Videocast - All Events - October 28, 2013 Category: Journals (General) Tags: Upcoming Events Source Type: video

Illumination of innate and adpative immunity in the brain
NIH Director's Seminar Series Immune responses are highly dynamic and often shaped by the tissue in which they develop. The Viral Immunology and Intravital Imaging Unit is interested in defining the mechanics of innate and adaptive immune responses in living tissues. To accomplish this, we use a real-time imaging technique referred to as two-photon laser scanning microscopy. This approach enables us to peer into lymphoid and non-lymphoid tissues as they experience different immunological perturbations. We are particularly interested in understanding the dynamics of immune responses that develop to infections (viruses,...
Source: Videocast - All Events - February 1, 2013 Category: Journals (General) Tags: Upcoming Events Source Type: video