NCCIH Announces Availability of Frequently Asked Questions (FAQs) for RFA-AT-22-003: HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management (R61/R33, Clinical Trial Required)
Notice NOT-AT-22-011 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2022 Category: Research Source Type: funding

HEAL Initiative: Discovery and Functional Evaluation of Human Pain-associated Genes and Cells (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-018 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement is to support research that uses human tissue or cells to generate comprehensive datasets for the discovery and characterization of functional genetic elements, epigenetic signatures, and molecular/cellular pathways that underlie human pain transduction, transmission, and processing. This FOA will support concerted multidisciplinary team science efforts that apply large-scale high-throughput approaches on tissues involved in human pain processing as part of the NIH HEAL Initiatives Program ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 4, 2022 Category: Research Source Type: funding

HEAL Initiative: Human Pain-associated Genes and Cells Data Coordination and Integration Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-021 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity announcement is to support a Human Pain-associated Genes and Cells Data Coordination and Integration Center as part of the NIH HEAL Initiatives Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of Human Pain (PRECISION Human Pain).The Data Coordination and Integration Center will curate, harmonize, and integrate comprehensive -omics and cellular function datasets generated by companion U19 Centers for Discovery and Functional Evaluation of Human Pain-...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 4, 2022 Category: Research Source Type: funding

Integrative Research in Gynecologic Health (R01 Clinical Trial Optional)
Funding Opportunity RFA-HD-23-006 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to encourage integrated and synergistic research in the study of uterine fibroids, endometriosis, adenomyosis, gynecologic pain syndromes, and/or pelvic floor disorders. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2022 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)
Notice NOT-NS-22-070 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 28, 2022 Category: Research Source Type: funding

Notice of Technical Assistance Webinar for RFA-AR-22-009, HEAL Initiative: Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN)
Notice NOT-AR-22-016 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 24, 2022 Category: Research Source Type: funding

Advancing Research on Mechanisms and Management of Pain for Diseases and Conditions within NIDDK Mission Areas (R01 Clinical Trial Optional)
Funding Opportunity RFA-DK-22-005 from the NIH Guide for Grants and Contracts. The impact of pain on patient quality of life for diseases and conditions within the mission of the NIDDK is enormous. Despite prior research efforts, our understanding of the underlying biological and clinical contributors of pain remains limited. In addition, new clinical management strategies that better measure, predict, and target pain and improve upon current interventions, such as opioids, are critically needed. The current Funding Opportunity Announcement will address these needs through solicitation of broad investigator-initiated re...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 21, 2022 Category: Research Source Type: funding

HEAL Initiative: Secondary Analysis and Integration of Existing Data Related to Acute and Chronic Pain Development or Management in Humans (R21 Clinical Trials Not Allowed)
Funding Opportunity RFA-DE-22-011 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is soliciting applications to support the analysis of existing data and resources from humans, including large, diverse national research cohorts, to answer specific questions about the development of human acute or chronic pain and its management. Applications may be related to, but must be distinct from, the specific aims of the original data collection. Generation of new primary data with this funding is not allowed. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 21, 2022 Category: Research Source Type: funding

Emergency Awards: HEAL Initiative- New Innovator Award (DP2 Clinical Trial Not Allowed)
Funding Opportunity RFA-TR-22-013 from the NIH Guide for Grants and Contracts. NCATS is issuing this FOA in response to the declared public health emergency issued by the Secretary, HHS. Please see Determination that a Public Health Emergency Exists Nationwide as the Result of the Opioid Crisis as renewed in Renewal of the Determination that a Public Health Emergency Exists Nationwide as the Result of the Continued Consequences of the Opioid Crisis. The Helping End Addiction Long-Term (HEAL) New Innovator Award supports a postdoctoral or newly independent Early Stage Investigator of exceptional creativity who proposes n...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 20, 2022 Category: Research Source Type: funding

HEAL Initiative: Advancing Health Equity in Pain and Comorbidities (R61/R33 Clinical Trial Required)
Funding Opportunity RFA-NS-22-037 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to solicit applications to develop, test, and implement, novel, multi-level, culturally appropriate interventions and/or adapt, test and evaluate efficacy and effectiveness of existing interventions in NIH designated populations that disproportionately experience negative health outcomes (HDP). Desired outcomes of these interventions include reduction of pain and pain-related symptoms and improvement in patient satisfaction, and overall health outcomes, including function and quality of ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 20, 2022 Category: Research Source Type: funding

Emergency Awards: HEAL Initiative-Limited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Research Network (ERN) (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-TR-22-012 from the NIH Guide for Grants and Contracts. NCATS is issuing this FOA in response to the declared public health emergency issued by the Secretary, HHS. Please see Determination that a Public Health Emergency Exists Nationwide as the Result of the Opioid Crisis as renewed in Renewal of the Determination that a Public Health Emergency Exists Nationwide as the Result of the Continued Consequences of the Opioid Crisis. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to continue support of Resource Center activities funded under RFA-TR-15-002 and RFA-TR...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 19, 2022 Category: Research Source Type: funding

HEAL Initiative: National K12 Clinical Pain Career Development Program (K12 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-045 from the NIH Guide for Grants and Contracts. This FOA will support early career clinical pain scientists development as a means to enhance the clinical pain research workforce. Under this award, promising early-career clinician-scientists will have access to high-quality mentorship that will promote their successful transition to independent research careers in academic settings. Clinicians in their last year of residency/fellowship/post-doctoral training, or in their first year of an independent faculty position, can apply to the awarded HCPDP national program for support, which is int...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 10, 2022 Category: Research Source Type: funding

HEAL Initiative: Coordinating Center for National Pain Scientists Career Development (R24 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-046 from the NIH Guide for Grants and Contracts. There is an urgent need for more research to establish best practices in the pain management field, however, there is a limited workforce pipeline of pain researchers to meet NIHs long-term goals of providing effective non-opioid options for the treatment of pain conditions and better pain management overall. The Interagency Pain Research Coordinating Committee (IPRCC) has identified the workforce problem as a barrier for new pain research, and has identified factors that contributed to it such as barriers to entry into the field of pain rese...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 10, 2022 Category: Research Source Type: funding

HEAL Initiative: Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN) (UC2 Clinical Trial Not Allowed)
Funding Opportunity RFA-AR-22-009 from the NIH Guide for Grants and Contracts. HEAL Initiative: Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN) (UC2 Clinical Trial Not Allowed) - The purpose of this Funding Opportunity Announcement is to solicit cooperative agreement applications to support interdisciplinary teams that will work together to form the Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN). The goal of RE-JOIN will be to define the innervation of the different tissues, which collectively form the joints, by sensory neurons that mediate the sensation of pain. Knowled...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 10, 2022 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Administrative Supplements for NIDCR Grants to Support Pain-Focused High Priority Research Areas
Notice NOT-DE-22-002 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 10, 2022 Category: Research Source Type: funding