HEAL Initiative: Interdisciplinary Teams to Elucidate the Mechanisms of Device-Based Pain Relief (RM1 Clinical Trial Optional)
Funding Opportunity RFA-NS-22-016 from the NIH Guide for Grants and Contracts. More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 31, 2021 Category: Research Source Type: funding
HEAL Initiative: Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements to Support Strategies to Advance the Study of Chronic Overlapping Pain Conditions (COPCs)
Notice NOT-NS-21-068 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 25, 2021 Category: Research Source Type: funding
Notice of Change: Extension of PA-18-937 "Research on Chronic Overlapping Pain Conditions (R01 Clinical Trial Optional)"
Notice NOT-NS-22-014 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 19, 2021 Category: Research Source Type: funding
Notice of Change: Extension of PA-18-939 "Research on Chronic Overlapping Pain Conditions (R21 Clinical Trial Not Allowed)"
Notice NOT-NS-22-015 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 19, 2021 Category: Research Source Type: funding
Feasibility Studies that Explore Healthy and Diseased Temporomandibular Joints (TMJ) using Single Cell Multi-Omic Analyses (UH2/UH3 Clinical Trial Not Allowed)
Funding Opportunity RFA-DE-22-005 from the NIH Guide for Grants and Contracts. The goal of this initiative is to encourage research focused on deciphering the cellular and molecular mechanisms underpinning temporomandibular joint disorders (TMJD) pain and tissue dysfunction using single-cell omics approaches. Delineation of cellular and molecular mechanisms that mediate TMJD resolution and homeostasis are also desired. Identification of cell populations and their effector pathways, in TMJD target tissue (e.g. synovial fluid, muscle, skin), as 1) molecular disease classifiers allowing for patient stratification, 2) diagn...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 12, 2021 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management
Notice NOT-AT-21-012 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 20, 2021 Category: Research Source Type: funding
Notice of NIAMS Participation in RFA-NS-20-010, "HEAL Initiative: HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)"
Notice NOT-AR-21-025 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 15, 2021 Category: Research Source Type: funding
Notice of NIAMS Participation in RFA-NS-20-008, "HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)"
Notice NOT-AR-21-024 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 15, 2021 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Interdisciplinary Teams to Elucidate the Mechanisms of Device-Based Pain Relief (RM1 Clinical Trial Optional)
Notice NOT-NS-21-066 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 23, 2021 Category: Research Source Type: funding
HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-21-029 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-21-016: The goal of this funding opportunity announcement (FOA) is to solicit Initial Analgesic Development R61 applications that propose 2-year exploratory/planning awards that are expected to enable a future application for RFA-NS-21-015 HEAL Initiative: Team Research - for Initial Translational Efforts in Non-addictive Analgesic Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed). Thus, the limited scope of aims and approach of these applications are expected to establish a strong research team, f...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 8, 2021 Category: Research Source Type: funding
Notice of Special Interest to Encourage Eligible NIH HEAL Initiative Awardees to Apply for Administrative Supplements to Support Career Enhancement Related to Clinical Research on Pain (Admin Supp Clinical Trial Not Allowed)
Notice NOT-NS-21-048 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 23, 2021 Category: Research Source Type: funding
New Reviewer Resources for Assessing the Vertebrate Animals Section
Developing your application and wondering how reviewers will assess the vertebrate animal section (VAS)? If so, we encourage you to check out these two new resources, a training module and cheat sheet, which are available on the Consolidated List of Reviewer Documents webpage. The training module highlights what reviewers need to know about the information that must be included in the VAS and assists reviewers in evaluating the VAS. The cheat sheet provides an overview of the criteria required in the VAS including justifications for animal use and interventions to minimize pain, discomfort, and injury.
Want to know more ...
Source: NIH Extramural Nexus - April 14, 2021 Category: Research Authors: NIH Staff Tags: New Resources Animal Welfare application Peer review Source Type: funding
HEAL Initiative: Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-21-015 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) is part of a suite of FOAs to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal of this FOA is to support team-based research projects to develop assays, screening and early optimization work to develop a non-addictive therapeutic to treat pain. Discovery and validation of pharmacodynamic markers efficacy and pharmacokinetic/pharmacodynamic (PK/PD) studies are also responsive. The result of the project should be to advance a hit or lead to the point w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 11, 2021 Category: Research Source Type: funding
HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (R34 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-21-016 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity announcement (FOA) is to solicit Initial Analgesic Development R34 applications that propose 2-year exploratory/planning awards that are expected to enable a future application for RFA-NS-21-015 HEAL Initiative: Team Research - for Initial Translational Efforts in Non-addictive Analgesic Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed). Thus, the limited scope of aims and approach of these applications are expected to establish a strong research team, feasibility, validity, or o...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 11, 2021 Category: Research Source Type: funding
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
Funding Opportunity RFA-DA-21-030 from the NIH Guide for Grants and Contracts. enter purposeChronic Non-Cancer Pain (CP) and Opioid Use Disorder (OUD) overlap significantly and patients with both conditions present particular clinical complexity. CP adversely impacts OUD treatment adherence and recovery, while the presence of dependence stigmatizes treatment services for chronic pain, often resulting in insufficient pain treatment. Fundamentally, the healthcare system lacks the expertise and effective interventions for managing comorbid CP and OUD, leaving patients suffering and at risk for poor outcomes. The National I...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 11, 2021 Category: Research Source Type: funding
