Current status of opioid prescription in South Korea using narcotics information management system
CONCLUSIONS: : Opioid prescription in South Korea features a high proportion of oral formulations, tertiary hospital administration, pharmacy dispensing, and elderly patients. Sustained education and surveillance of patients and healthcare providers is required.PMID:38061773 | DOI:10.3344/kjp.23234 (Source: Korean Journal of Pain)
Source: Korean Journal of Pain - December 7, 2023 Category: Anesthesiology Authors: Soo-Hyuk Yoon Jeongsoo Kim Susie Yoon Ho-Jin Lee Source Type: research
The Christmas adverse event syndrome: An analysis of the WHO pharmacovigilance database
CONCLUSIONS: Our study shows that a range of drugs adverse events are more frequently reported at Christmas compared to other periods of the year, notably psychiatric disorders, infections, and skin disorders.PMID:38057212 | DOI:10.1016/j.therap.2023.11.004 (Source: Therapie)
Source: Therapie - December 6, 2023 Category: Psychiatry & Psychology Authors: Alex Hlavaty Matthieu Roustit Marc Manceau Jean-Luc Cracowski Charles Khouri Source Type: research
The Christmas adverse event syndrome: An analysis of the WHO pharmacovigilance database
CONCLUSIONS: Our study shows that a range of drugs adverse events are more frequently reported at Christmas compared to other periods of the year, notably psychiatric disorders, infections, and skin disorders.PMID:38057212 | DOI:10.1016/j.therap.2023.11.004 (Source: Therapie)
Source: Therapie - December 6, 2023 Category: Psychiatry & Psychology Authors: Alex Hlavaty Matthieu Roustit Marc Manceau Jean-Luc Cracowski Charles Khouri Source Type: research
The Christmas adverse event syndrome: An analysis of the WHO pharmacovigilance database
CONCLUSIONS: Our study shows that a range of drugs adverse events are more frequently reported at Christmas compared to other periods of the year, notably psychiatric disorders, infections, and skin disorders.PMID:38057212 | DOI:10.1016/j.therap.2023.11.004 (Source: Therapie)
Source: Therapie - December 6, 2023 Category: Psychiatry & Psychology Authors: Alex Hlavaty Matthieu Roustit Marc Manceau Jean-Luc Cracowski Charles Khouri Source Type: research
A Retrospective Observational Study of Factors Affecting the Efficacy of Concurrent Prescription of Naldemedine for Opioid-Induced Constipation Caused by Oxycodone Tablets
Biol Pharm Bull. 2023;46(12):1826-1831. doi: 10.1248/bpb.b23-00487.ABSTRACTNaldemedine is indicated for the treatment of opioid-induced constipation (OIC), but reports on its efficacy in preventing OIC are few. Therefore, we retrospectively investigated factors affecting the efficacy of concurrent prescription of naldemedine on OIC. Outpatients with cancer who were started on oxycodone 10 mg/d were included in the study. The eligible patients were classified by their physicians into the following three groups: Group A used regular laxatives before the introduction of oxycodone and initiated naldemedine treatment simultaneo...
Source: Biological and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Masami Yamada Yumi Jimaru Sari Torii Naoko Mitsuba Kazushige Takahashi Source Type: research
A Retrospective Observational Study of Factors Affecting the Efficacy of Concurrent Prescription of Naldemedine for Opioid-Induced Constipation Caused by Oxycodone Tablets
Biol Pharm Bull. 2023;46(12):1826-1831. doi: 10.1248/bpb.b23-00487.ABSTRACTNaldemedine is indicated for the treatment of opioid-induced constipation (OIC), but reports on its efficacy in preventing OIC are few. Therefore, we retrospectively investigated factors affecting the efficacy of concurrent prescription of naldemedine on OIC. Outpatients with cancer who were started on oxycodone 10 mg/d were included in the study. The eligible patients were classified by their physicians into the following three groups: Group A used regular laxatives before the introduction of oxycodone and initiated naldemedine treatment simultaneo...
Source: Biological and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Masami Yamada Yumi Jimaru Sari Torii Naoko Mitsuba Kazushige Takahashi Source Type: research
A Retrospective Observational Study of Factors Affecting the Efficacy of Concurrent Prescription of Naldemedine for Opioid-Induced Constipation Caused by Oxycodone Tablets
Biol Pharm Bull. 2023;46(12):1826-1831. doi: 10.1248/bpb.b23-00487.ABSTRACTNaldemedine is indicated for the treatment of opioid-induced constipation (OIC), but reports on its efficacy in preventing OIC are few. Therefore, we retrospectively investigated factors affecting the efficacy of concurrent prescription of naldemedine on OIC. Outpatients with cancer who were started on oxycodone 10 mg/d were included in the study. The eligible patients were classified by their physicians into the following three groups: Group A used regular laxatives before the introduction of oxycodone and initiated naldemedine treatment simultaneo...
Source: Biological and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Masami Yamada Yumi Jimaru Sari Torii Naoko Mitsuba Kazushige Takahashi Source Type: research
Postdischarge Opioid Prescription after Cesarean: A Quality Improvement Initiative
Conclusion Discharge opioid prescribing based on inpatient use after cesarean reduces the number of opioids prescribed without increasing the number of pain-related encounters after discharge. A simple algorithm may ensure compliance from prescribers.
Key Points
[...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - November 30, 2023 Category: Perinatology & Neonatology Authors: Pellino, Katherine T. Kershner, Alexandra Peterson, Erika L. Tags: Original Article Source Type: research
Study on the association between adverse drug reactions to opioids and gene polymorphisms: a case-case-control study
CONCLUSION: Polymorphism of ABCB1 (062rs1045642) is related to ADRs caused by oxycodone, and the incidence of ADRs is higher with the allele T. Polymorphism of ABCB1 is expected to become a clinical predictor of ADRs to oxycodone, and attention should be given to the occurrence of serious ADRs in patients with ABCB1 (062rs1045642) CT and TT genotypes.PMID:37990344 | DOI:10.1186/s40360-023-00708-4 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 22, 2023 Category: Drugs & Pharmacology Authors: Jing Yang Ying-Zi Sun Qun-Fang Li Zheng Fu Yu-Yao Guan Chao Song Lei Zheng Source Type: research
Study on the association between adverse drug reactions to opioids and gene polymorphisms: a case-case-control study
CONCLUSION: Polymorphism of ABCB1 (062rs1045642) is related to ADRs caused by oxycodone, and the incidence of ADRs is higher with the allele T. Polymorphism of ABCB1 is expected to become a clinical predictor of ADRs to oxycodone, and attention should be given to the occurrence of serious ADRs in patients with ABCB1 (062rs1045642) CT and TT genotypes.PMID:37990344 | PMC:PMC10662635 | DOI:10.1186/s40360-023-00708-4 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 22, 2023 Category: Drugs & Pharmacology Authors: Jing Yang Ying-Zi Sun Qun-Fang Li Zheng Fu Yu-Yao Guan Chao Song Lei Zheng Source Type: research
The Role of Non-Pharmaceutical Fentanyl-Contaminated Counterfeit Oxycodone in Increasing Opioid Overdoses: A Commentary Review
Conclusion: Clinicians should counsel patients at risk for opioid misuse on the risks of counterfeit oxycodone.Prim Care Companion CNS Disord 2023;25(6):22nr03433.Author affiliations are listed at the end of this article.PMID:37976226 | DOI:10.4088/PCC.22nr03433 (Source: The Primary Care Companion for CNS Disorders)
Source: The Primary Care Companion for CNS Disorders - November 17, 2023 Category: Primary Care Authors: Grace E Hartmann Roopa Sethi Source Type: research
The Role of Non-Pharmaceutical Fentanyl-Contaminated Counterfeit Oxycodone in Increasing Opioid Overdoses: A Commentary Review
Conclusion: Clinicians should counsel patients at risk for opioid misuse on the risks of counterfeit oxycodone.Prim Care Companion CNS Disord 2023;25(6):22nr03433.Author affiliations are listed at the end of this article.PMID:37976226 | DOI:10.4088/PCC.22nr03433 (Source: Primary Care)
Source: Primary Care - November 17, 2023 Category: Primary Care Authors: Grace E Hartmann Roopa Sethi Source Type: research
