Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Diagnostic Accuracy of Plain Computed Tomography Temporal Bone in Detection of Pre-operative Ossicular Status versus Per-operative Findings in Chronic Otitis Media
This study aims to check the diagnostic accuracy of computed tomography temporal bone for the detection of ossicular erosion in comparison with the surgical findings taken as a gold standard. The use of this investigation as an adjunct can prove to be helpful in planning mastoid exploration as well as a primary reconstruction surgery especially in mucosal and early squamosal diseases. It ’s a cross-sectional validation study done on 50 patients with chronic otitis media (both mucosal and squamous type) from July 2022 to November 2023. Patients underwent CT scanning of temporal bone and ossicular status was reported by th...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - March 7, 2024 Category: ENT & OMF Source Type: research

Bioequivalence Study of Tebipenem Pivoxil in Healthy Chinese Adults
ConclusionPreparations T and R of TP were bioequivalent in the fasting and postprandial groups in clinical trials, and TP was safe. (Source: Drugs in R&D)
Source: Drugs in R&D - March 7, 2024 Category: Drugs & Pharmacology Source Type: research

Do Decreased Mastoid Pneumatization, Bilateral Involvement and Eustachian Tube Function Affect the Success of Type 1 Tympanoplasty?
CONCLUSION: Preoperative air-bone gap average is higher in ears with decreased mastoid pneumatization, and postoperative air-bone gap closure is higher in unilateral patients. Mastoid ventilation does not make a significant difference in the success of type 1 tympanoplasty. On the other hand, our results support that ET dysfunction can be effective in the occurrence of chronic otitis media (COM).PMID:38440578 | PMC:PMC10908985 | DOI:10.1007/s12070-023-04340-w (Source: Hand Surgery)
Source: Hand Surgery - March 5, 2024 Category: Surgery Authors: Serhan Keskin Arzu Tatl ıpınar Emrah K ınal Source Type: research

Do Decreased Mastoid Pneumatization, Bilateral Involvement and Eustachian Tube Function Affect the Success of Type 1 Tympanoplasty?
CONCLUSION: Preoperative air-bone gap average is higher in ears with decreased mastoid pneumatization, and postoperative air-bone gap closure is higher in unilateral patients. Mastoid ventilation does not make a significant difference in the success of type 1 tympanoplasty. On the other hand, our results support that ET dysfunction can be effective in the occurrence of chronic otitis media (COM).PMID:38440578 | PMC:PMC10908985 | DOI:10.1007/s12070-023-04340-w (Source: Hand Surgery)
Source: Hand Surgery - March 5, 2024 Category: Surgery Authors: Serhan Keskin Arzu Tatl ıpınar Emrah K ınal Source Type: research

Analysis of the effect of reconstructing the ossicular chain under otoendoscopy with and without a stapes superstructure
CONCLUSIONS AND SIGNIFICANCE: The stapes superstructure has an important positive effect on the postoperative outcome of endoscopic ossicular chain reconstruction.PMID:38436696 | DOI:10.1080/00016489.2024.2322965 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - March 4, 2024 Category: ENT & OMF Authors: Yufeng Yang Wenjing Gui Cong Wu Xianmin Wu Source Type: research

Analysis of the effect of reconstructing the ossicular chain under otoendoscopy with and without a stapes superstructure
CONCLUSIONS AND SIGNIFICANCE: The stapes superstructure has an important positive effect on the postoperative outcome of endoscopic ossicular chain reconstruction.PMID:38436696 | DOI:10.1080/00016489.2024.2322965 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - March 4, 2024 Category: ENT & OMF Authors: Yufeng Yang Wenjing Gui Cong Wu Xianmin Wu Source Type: research

Analysis of the effect of reconstructing the ossicular chain under otoendoscopy with and without a stapes superstructure
CONCLUSIONS AND SIGNIFICANCE: The stapes superstructure has an important positive effect on the postoperative outcome of endoscopic ossicular chain reconstruction.PMID:38436696 | DOI:10.1080/00016489.2024.2322965 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - March 4, 2024 Category: ENT & OMF Authors: Yufeng Yang Wenjing Gui Cong Wu Xianmin Wu Source Type: research

Analysis of the effect of reconstructing the ossicular chain under otoendoscopy with and without a stapes superstructure
CONCLUSIONS AND SIGNIFICANCE: The stapes superstructure has an important positive effect on the postoperative outcome of endoscopic ossicular chain reconstruction.PMID:38436696 | DOI:10.1080/00016489.2024.2322965 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - March 4, 2024 Category: ENT & OMF Authors: Yufeng Yang Wenjing Gui Cong Wu Xianmin Wu Source Type: research