The effectiveness of multimodal rehabilitation interventions for the management of cervical radiculopathy in adults: an updated systematic review from the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration
Conclusion: The evidence suggests that some multimodal rehabilitation care may provide small and trivial reduction in neck pain or improvement in function to patients with cervical radiculopathy. However, the effectiveness of these interventions has not been demonstrated and more research is needed to determine the effectiveness of multimodal rehabilitation interventions for the management of adults with cervical radiculopathy.PMID:35797062 | DOI:10.2340/jrm.v54.2799 (Source: Journal of Rehabilitation Medicine)
Source: Journal of Rehabilitation Medicine - July 7, 2022 Category: Rehabilitation Authors: Fabrice Mallard J Wong N Lemeunier P C ôté Source Type: research
Depression in Patients with Parkinson ’s Disease: Current Understanding of its Neurobiology and Implications for Treatment
AbstractDepression is one of the most frequent and burdensome non-motor symptoms in Parkinson ’s disease (PD), across all stages. Even when its severity is mild, PD depression has a great impact on quality of life for these patients and their caregivers. Accordingly, accurate diagnosis, supported by validated scales, identification of risk factors, and recognition of motor and non-motor sy mptoms comorbid to depression are critical to understanding the neurobiology of depression, which in turn determines the effectiveness of dopaminergic drugs, antidepressants and non-pharmacological interventions. Recent advances using ...
Source: Drugs and Aging - June 16, 2022 Category: Geriatrics Source Type: research
COVID-19 Prognosis in Association with Antidepressant
Use
Conclusion This study revealed an association between antidepressants and
COVID-19 prognosis. SSRIs were significantly associated with a lower risk of
severe outcomes, whereas TCAs were related to the poor prognosis of
COVID-19. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - June 2, 2022 Category: Psychiatry Authors: Min, Kyung Hyun Kim, Tae Hyeok Oh, Soo Jin Kim, Woorim Lee, Kyung Eun Tags: Original Paper Source Type: research
A rapid and versatile microfluidic method for the simultaneous extraction of polar and non-polar basic pharmaceuticals from human urine
Anal Chim Acta. 2022 May 22;1208:339829. doi: 10.1016/j.aca.2022.339829. Epub 2022 Apr 11.ABSTRACTIn sample preparation, simultaneous extraction of analytes of very different polarity from biological matrixes represents a challenge. In this work, verapamil hydrochloride (VRP), amitriptyline (AMP), tyramine (TYR), atenolol (ATN), metopropol (MTP) and nortriptyline (NRP) were used as basic model analytes and simultaneously extracted from urine samples by liquid-phase microextraction (LPME) in a microfluidic device. The model analytes (target compounds) were pharmaceuticals with 0.4 < log P < 5. Different organic solven...
Source: Analytica Chimica Acta - May 7, 2022 Category: Chemistry Authors: Elia Santigosa Stig Pedersen-Bjergaard Pablo Gim énez-Gómez Mar ía Muñoz Mar ía Ramos-Payán Source Type: research
A rapid and versatile microfluidic method for the simultaneous extraction of polar and non-polar basic pharmaceuticals from human urine
Anal Chim Acta. 2022 May 22;1208:339829. doi: 10.1016/j.aca.2022.339829. Epub 2022 Apr 11.ABSTRACTIn sample preparation, simultaneous extraction of analytes of very different polarity from biological matrixes represents a challenge. In this work, verapamil hydrochloride (VRP), amitriptyline (AMP), tyramine (TYR), atenolol (ATN), metopropol (MTP) and nortriptyline (NRP) were used as basic model analytes and simultaneously extracted from urine samples by liquid-phase microextraction (LPME) in a microfluidic device. The model analytes (target compounds) were pharmaceuticals with 0.4 < log P < 5. Different organic solven...
Source: Analytica Chimica Acta - May 7, 2022 Category: Chemistry Authors: Elia Santigosa Stig Pedersen-Bjergaard Pablo Gim énez-Gómez Mar ía Muñoz Mar ía Ramos-Payán Source Type: research
A rapid and versatile microfluidic method for the simultaneous extraction of polar and non-polar basic pharmaceuticals from human urine
Anal Chim Acta. 2022 May 22;1208:339829. doi: 10.1016/j.aca.2022.339829. Epub 2022 Apr 11.ABSTRACTIn sample preparation, simultaneous extraction of analytes of very different polarity from biological matrixes represents a challenge. In this work, verapamil hydrochloride (VRP), amitriptyline (AMP), tyramine (TYR), atenolol (ATN), metopropol (MTP) and nortriptyline (NRP) were used as basic model analytes and simultaneously extracted from urine samples by liquid-phase microextraction (LPME) in a microfluidic device. The model analytes (target compounds) were pharmaceuticals with 0.4 < log P < 5. Different organic solven...
Source: Analytica Chimica Acta - May 7, 2022 Category: Chemistry Authors: Elia Santigosa Stig Pedersen-Bjergaard Pablo Gim énez-Gómez Mar ía Muñoz Mar ía Ramos-Payán Source Type: research
A rapid and versatile microfluidic method for the simultaneous extraction of polar and non-polar basic pharmaceuticals from human urine
Anal Chim Acta. 2022 May 22;1208:339829. doi: 10.1016/j.aca.2022.339829. Epub 2022 Apr 11.ABSTRACTIn sample preparation, simultaneous extraction of analytes of very different polarity from biological matrixes represents a challenge. In this work, verapamil hydrochloride (VRP), amitriptyline (AMP), tyramine (TYR), atenolol (ATN), metopropol (MTP) and nortriptyline (NRP) were used as basic model analytes and simultaneously extracted from urine samples by liquid-phase microextraction (LPME) in a microfluidic device. The model analytes (target compounds) were pharmaceuticals with 0.4 < log P < 5. Different organic solven...
Source: Analytica Chimica Acta - May 7, 2022 Category: Chemistry Authors: Elia Santigosa Stig Pedersen-Bjergaard Pablo Gim énez-Gómez Mar ía Muñoz Mar ía Ramos-Payán Source Type: research
A rapid and versatile microfluidic method for the simultaneous extraction of polar and non-polar basic pharmaceuticals from human urine
Anal Chim Acta. 2022 May 22;1208:339829. doi: 10.1016/j.aca.2022.339829. Epub 2022 Apr 11.ABSTRACTIn sample preparation, simultaneous extraction of analytes of very different polarity from biological matrixes represents a challenge. In this work, verapamil hydrochloride (VRP), amitriptyline (AMP), tyramine (TYR), atenolol (ATN), metopropol (MTP) and nortriptyline (NRP) were used as basic model analytes and simultaneously extracted from urine samples by liquid-phase microextraction (LPME) in a microfluidic device. The model analytes (target compounds) were pharmaceuticals with 0.4 < log P < 5. Different organic solven...
Source: Analytica Chimica Acta - May 7, 2022 Category: Chemistry Authors: Elia Santigosa Stig Pedersen-Bjergaard Pablo Gim énez-Gómez Mar ía Muñoz Mar ía Ramos-Payán Source Type: research
