Hunting Disease-Causing Genetic Variants
Dr. Miriam Meisler. Credit: University of Michigan Medical School. “In my lab, we’ve been gene hunters—starting with visible phenotypes, or characteristics, and searching for the responsible genes,” says Miriam Meisler, Ph.D., the Myron Levine Distinguished University Professor at the University of Michigan Medical School in Ann Arbor. During her career, Dr. Meisler has identified the functions of multiple genes and has shown how genetic variants, or mutations, can impact human health. Becoming a Scientist Dr. Meisler had a strong interest in science as a child, which she credits to “growing up at the tim...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 29, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Genes Injury and Illness Diseases DNA Profiles Research Organisms Scientific Process Source Type: blogs

Medical advances can often stir up ethical issues
An excerpt from Pluck: Lessons We Learned for Improving Healthcare and the World, published by Silicon Valley Press. We met Joseph S. Murtaugh, our new chief at the National Institutes of Health, for the first time on July 3, 1967. He sat behind his desk, looking every bit like Hollywood’s image of a 1960’s civilRead more …Medical advances can often stir up ethical issues originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 28, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/alfred-sadler-and-blair-sadler" rel="tag" data-wpel-link="internal" > Alfred Sadler, MD and Blair Sadler, JD < /a > < /span > Tags: Policy Endocrinology Source Type: blogs

Trial By Error: Interview With Mt Sinai ’ s David Putrino
By David Tuller, DrPH David Putrino is a neuroscientist and physical therapist at Mt. Sinai Hospital in New York. He runs a research lab and a rehabilitation center that quickly became a magnet for patients grappling with what has come to be known as long Covid–what the US National Institutes of Health calls post-acute sequelae […] (Source: virology blog)
Source: virology blog - May 12, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Long Covid Mt Sinai post-exertional malaise Putrino Source Type: blogs

Trial By Error: An Interview With Mt Sinai ’ s David Putrino About Long Covid, ME/CFS, and Related Issues
By David Tuller, DrPH David Putrino is a neuroscientist and physical therapist at Mt. Sinai Hospital in New York. He runs a research lab and a rehabilitation center that quickly became a magnet for patients grappling with what has come to be known as long Covid–what the US National Institutes of Health calls post-acute sequelae […] (Source: virology blog)
Source: virology blog - May 12, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Long Covid Mt Sinai post-exertional malaise Putrino Source Type: blogs

Pathways: The Vaccine Science Issue
Cover of Pathways student magazine. NIGMS is pleased to bring you Pathways: The Vaccine Science Issue [PDF], which explains how the messenger RNA (mRNA) vaccines for COVID-19 work and how they were developed. Building on years of research, scientists were able to create these vaccines, thoroughly test them, and get them to the public as quickly as possible—while still making sure they were safe and effective. Pathways, designed for students in grades 6 through 12, aims to build awareness of basic biomedical science and its importance to health while inspiring careers in research. All materials in the collection ar...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 6, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness COVID-19 Infectious Diseases RNA Source Type: blogs

Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Overseas Health IT Links – 19th March, 2022.
Here are a few I came across last week. Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment. ----- https://healthitanalytics.com/news/nih-grant-supports-creation-of-non-biased-machine-learning-algorithm NIH Grant Supports Creation of Non-Biased Machine-Learning Algorithm Following the reception of a grant from the National Institutes of Health, Dascena will work to create an unbiased algorithm to help diagnose and treat acute coronary syndrome. By Mark Melc...
Source: Australian Health Information Technology - March 19, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 2)
By DAVID WARMFLASH, MD This is part 2 of David Warmlash’s takedown of Robert W. Malone’s appearance (transcript) on the Rogan podcast. Part 1 is here Menstruation and Fertility Much more than the line about reproductive damage in the Wisconsin News clip that we used to open the story, Malone used the Rogan interview to dive more deeply into the topic, starting with:  …there’s a huge number of dysmenorrhea and menometrorrhagia… By that, he meant excessive menstrual cramping and very heavy, often irregular, bleeding, which he followed up with: …they DENY it… Judging by other parts ...
Source: The Health Care Blog - March 18, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs

Painless Nasogastric Tube Placement
​A 6-year-old boy presented with intermittent abdominal pain, nausea, and vomiting. Because his abdominal examination was unremarkable, the pain intermittent, and constipation a possibility, we provided an enema along with an abdominal pain workup but no radiographs. His pain improved, the abdominal labs were unremarkable, and the child tolerated an oral fluid challenge after treatment with ondansetron.The mother was advised at discharge to return if she became concerned about her child's condition. They did return a few hours later for increased vomiting and abdominal pain. A CT scan demonstrated multiple dilated loops ...
Source: M2E Too! Mellick's Multimedia EduBlog - March 1, 2022 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Longevity.Technology Looks Back at 2021
A fair number of news and interest sites covering aging research and the development of therapies to treat aging as a medical condition have come and gone over the years. Longevity.Technology is one of the few that seems likely to stick around for a while, now that there is a growing longevity industry to cover, and thus the ability to bring in enough revenue in traditional ways to run a small professional journalism organization. The Longevity.Technology staff recently published a set of short retrospective articles, looking back on industry news from 2021; some are linked below. The lie of the longevity landscape ...
Source: Fight Aging! - January 3, 2022 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fall Risk: It ’ s All in Your Head
By HENRY MAHNCKE More than one in four senior citizens fall each year, making it the leading cause of both fatal and non-fatal injuries in older adults. Anyone with a loved one at high risk of falls can tell you it creates constant worry and curtails many of life’s pleasures. And, if that loved one has fallen and broken a hip, too many of those caregivers can share the oft-told tale of how that break was the beginning of the end. As our population grows and ages, the costs of this widespread risk multiply.  However, recent breakthroughs in the science of brain health demonstrate that we could be taking relatively ...
Source: The Health Care Blog - January 3, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Health Technology brain function BrainHQ falling National Institute of Aging National Institute of Health Source Type: blogs

Polymerase chain reaction (PCR) tests
This is the test you need to get if you test positive with a lateral flow test.  It is sent to a lab for processing.How does a PCR test work?Lots in the wide world of the internet about PCR tests, but (as with LFT results) a lot of it is about how you can get one, or the mechanics of taking one, with less about the science of how it works.If you have (as my students do) access to Clinical Key (Professional), there are book chapters about it.  Some chapters confirm you can use PCR in a specific clinical area or to diagnose a specific causative agent, but some may go into more detail about how it works.  ...
Source: Browsing - December 28, 2021 Category: Databases & Libraries Tags: COVID-19 Source Type: blogs

The devolution of conservatism
Rejection of some elements of science by some conservative factions is readily explainable. Creationists cling to a pre-scientific belief system. Climate change deniers (apart from those who have a personal financial stake in fossil fuels and put greed ahead of their granchildren ' s lives) are committed to the Free Market ™ religion, which is inconsistent with anthropogenic climate change, therefore climate change must be a hoax.However, rejection of medical science does not have such a ready explanation. The Director of the National Institutes of Health, Francis Collins, is retiring.He has given an exit interview to CB...
Source: Stayin' Alive - December 17, 2021 Category: American Health Source Type: blogs

The Cellular Senescence Network (SenNet) Program
Larger institutions such as the NIH are now beginning to invest a great deal more into fundamental research connected to cellular senescence. Twenty years ago it was clear enough that senescent cells were important in aging for the Strategies for Engineered Negligible Senescence (SENS) pioneers to include it in their initial scientific paper, but the topic was largely ignored by the mainstream of aging research. It took a decade to get to the point of a compelling animal study of targeted senescent cell clearance that convinced the rest of the research community. Five years after that the first senolytic-focused biotech co...
Source: Fight Aging! - October 28, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Clinical Trial Cost Transparency at the National Institutes of Health: Law and Policy Recommendations
This report discusses the need for cost transparency into... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - October 21, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs