Signal Transduction Knowledge Environment 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif | Science Signaling
A cytoplasmic motif in LAG3 mediates ligand-dependent inhibition of T cell receptor signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 3, 2023 Category: Science Source Type: news
Stress exhausts T cells | Science Signaling
Catecholamines associated with stress promote T cell exhaustion through the β1-adrenergic receptor. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 3, 2023 Category: Science Source Type: news
Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells | Science Signaling
The timing of transcriptional events in SARS-CoV-2 –infected cells reveals a host-targeted treatment. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 26, 2023 Category: Science Source Type: news
B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1 | Science Signaling
Mechanosensitive Ca2+ signaling in B cells underlies their preference for membrane-bound over soluble antigens. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 26, 2023 Category: Science Source Type: news
Stressed Hippo kinase turns to autophagy | Science Signaling
The Hippo kinase MAP4K2 takes a YAP-independent path to tolerating energy stress. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 26, 2023 Category: Science Source Type: news
Opposing roles of RUBCN isoforms in autophagy and memory B cell generation | Science Signaling
Two RUBCN isoforms exert distinct effects on autophagy and the differentiation of memory B cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 19, 2023 Category: Science Source Type: news
The lncRNA MIR99AHG directs alternative splicing of SMARCA1 by PTBP1 to enable invadopodia formation in colorectal cancer cells | Science Signaling
Colorectal cancer cells become invasive when an lncRNA alters the binding of a splicing factor. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 19, 2023 Category: Science Source Type: news
An ion channel ’s high five | Science Signaling
Switching between tetrameric and pentameric states regulates the pore size of the ion channel TRPV3. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 19, 2023 Category: Science Source Type: news
TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis | Science Signaling
Patients with eosinophilic esophagitis have more inflammatory T cells that respond to the cytokine TSLP. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 12, 2023 Category: Science Source Type: news
Fluoxetine restrains allergic inflammation by targeting an Fc ɛRI-ATP positive feedback loop in mast cells | Science Signaling
Fluoxetine inhibits IgE- and ATP-driven driven mast cell function in allergic inflammation. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 12, 2023 Category: Science Source Type: news
A spartin approach to lipophagy | Science Signaling
The autophagic degradation of lipid droplets requires the protein spartin. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 12, 2023 Category: Science Source Type: news
The Ca2+ channel ORAI1 is a regulator of oral cancer growth and nociceptive pain | Science Signaling
The Ca2+ channel ORAI1 promotes the growth of oral cancer cells and the pain they induce. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 5, 2023 Category: Science Source Type: news
Lysine lactylation regulates metabolic pathways and biofilm formation in Streptococcus mutans | Science Signaling
Sucrose stimulates lysine lactylation to alter metabolism in the oral bacterium Streptococcus mutans. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 5, 2023 Category: Science Source Type: news
Polycystin goes with the flow | Science Signaling
Asymmetric movement of a polycystin subunit may underlie the initial break in left-right asymmetry in mouse embryos. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 5, 2023 Category: Science Source Type: news
The E3/E4 ubiquitin ligase UFD-2 suppresses normal and oncogenic signaling mediated by a Raf ortholog in Caenorhabditis elegans | Science Signaling
A pathway that degrades wild-type and mutant forms of the C. elegans Raf ortholog LIN-45 is identified. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - August 29, 2023 Category: Science Source Type: news
