Signal Transduction Knowledge Environment This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
Viperin impairs the innate immune response through the IRAK1-TRAF6-TAK1 axis to promote Mtb infection | Science Signaling
A protein with protective effects during antiviral responses promotes infection by Mycobacterium tuberculosis. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 4, 2022 Category: Science Source Type: news
The kinase PLK1 promotes the development of Kras/Tp53-mutant lung adenocarcinoma through transcriptional activation of the receptor RET | Science Signaling
The kinase PLK1 fuels lung cancer growth by amplifying tumorigenic MAPK signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 4, 2022 Category: Science Source Type: news
Mutations in protein kinase C γ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition | Science Signaling
Biochemical characterization of mutations that cause a neurodegenerative disease provides pathological insight. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 27, 2022 Category: Science Source Type: news
TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22 | Science Signaling
The adaptor protein TRAF3 prevents a tyrosine phosphatase from blocking type I interferon signaling in T cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 27, 2022 Category: Science Source Type: news
Extracellular vesicles as central regulators of blood vessel function in cancer | Science Signaling
How extracellular vesicles released from cancer cells reprogram endothelial cells is discussed. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 27, 2022 Category: Science Source Type: news
Stress with ketamine tackles depression | Science Signaling
A stress hormone enables the antidepressant action of ketamine. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 27, 2022 Category: Science Source Type: news
Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion transport | Science Signaling
Coordination of mucus secretion with ion transport drives small intestinal crypt flushing. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 20, 2022 Category: Science Source Type: news
The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction | Science Signaling
A lentiviral protein induces the dimerization of a host tyrosine kinase to stimulate its activity. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 20, 2022 Category: Science Source Type: news
Expand, push, break, release, repair: A unique way to secrete macromolecules | Science Signaling
A unique secretory modality in the small intestine is discovered (Dolan et al., in 20 September 2022 issue). (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 20, 2022 Category: Science Source Type: news
Telomeres to go | Science Signaling
By acquiring telomeres from antigen-presenting cells, some T cells are protected from senescence. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 20, 2022 Category: Science Source Type: news
Fetal macrophages assist in the repair of ruptured amnion through the induction of epithelial-mesenchymal transition | Science Signaling
Repairs to ruptures in the amniotic sac may involve EMT elicited by fetal macrophages. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 13, 2022 Category: Science Source Type: news
Intestinal brush border formation requires a TMIGD1-based intermicrovillar adhesion complex | Science Signaling
An adhesion complex required for brush border formation in the intestine is identified. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 13, 2022 Category: Science Source Type: news
Pathogenic putrescine | Science Signaling
Urea metabolism in astrocytes that produce putrescine leads to memory impairment in Alzheimer ’s disease. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 13, 2022 Category: Science Source Type: news
c-di-AMP signaling is required for bile salt resistance, osmotolerance, and long-term host colonization by Clostridioides difficile | Science Signaling
Cyclic di-AMP degradation protects Clostridioides difficile from osmotic and bile salt stresses and promotes host colonization. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 6, 2022 Category: Science Source Type: news
Rounding out cyclic dinucleotide signaling in Clostridioides difficile: A role and a mechanism for c-di-AMP | Science Signaling
Biological roles for c-di-AMP in C. difficile are revealed (Oberkampf et al., in 6 September 2022). (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 6, 2022 Category: Science Source Type: news