Risk of thromboembolism in patients with COVID19 who are using hormonal contraception
Very little evidence exists on risk of VTE or increased COVID ‐19 severity for users of combined hormonal contraception (HC) vs. non‐users. Low certainty evidence suggests use of any HC method vs no contraceptive has little/no effect on hospitalization, intubation, or mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 13, 2023 Category: Consumer Health News Source Type: news

Investigation of SARS-CoV-2 variants: technical briefings, UKHSA (Updated 12th January 2023)
Technical briefing documents on novel SARS-CoV-2 variants. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Scabies: management advice for health professionals
Guidance for public health professionals to manage scabies cases and outbreaks, including recommendations for diagnosis, treatment and wider control measures. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

New breast cancer screening units to speed up diagnosis
Government pledges additional £ 10 million to deliver 29 new breast cancer screening units, 58 remote access upgrades and nearly 70 life-saving service upgrades to speed up diagnosis and treatment. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Shiga toxin-producing Escherichia coli: public health management
Guidance for public health professionals for the management of Shiga toxin-producing Escherichia coli (STEC) infection (including O157 and non-O157). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Death certificates for stillborn babies contain major errors
Medical certificates of stillbirth should record the likely cause of death for babies who died in the womb. However, research found major errors in most certificates. Many (43%) certificates had no recorded cause of death, even where the cause was identifiable. These certificates are intended to give parents information about why their baby died. For review boards, they may suggest steps that could have prevented the death. Following this study, researchers call for an independent review of the process of medical certification of stillbirth. This UK-wide study found numerous errors in the documents. Around 1 in 4 deaths ...
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Joint replacements: many people can safely wait 10 years for follow-up
Many people do not need a routine follow-up appointment after hip or knee replacement surgery. Research found that most people who had first replacement surgery using UK-recommended replacement joints can safely wait 10 years. People rarely develop problems after hip replacements or knee replacements. Services struggle to follow-up everyone after surgery, and many hospitals have either reduced or stopped follow-ups altogether. But there is little research into how safe this practice is. The team gathered information from previous research, national datasets, and from people with lived experience of joint replacements. Th...
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

UKHSA releases updated analysis on XBB.1.5, UKHSA (Updated 11th January 2023)
Latest updates on SARS-CoV-2 variants detected in the UK. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Hybrid closed loop systems for managing blood glucose levels in type 1 diabetes In development [GID-TA10845]Expected publication date: TBC
DRAFT guidance recommends use in people with difficulty managing condition and have average HbA1c of ≥64mmol/mol (8.0%) despite optimal management with ≥1 of following: continuous subcutaneous insulin infusion, real-time CGM or intermittently scanned continuous glucose monitoring (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Varicella vaccine (live): PGD template
Patient group direction (PGD) template to support outbreaks where chickenpox is co-circulating with scarlet fever in non-immune children from 9 months of age and adults. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 12, 2023 Category: Consumer Health News Source Type: news

Characteristics and Outcomes of Young Adult Patients with Severe Sepsis Admitted to Pediatric Intensive Care Units Versus Medical/Surgical Intensive Care Units.
Conclusions: Young adults with severe sepsis experience higher adjusted odds of mortality when treated in PICUs versus MICU/SICUs. However, there was no difference in length of stay. Variation in mortality is likely due to significant differences in the patient populations, including comorbidity status. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2023 Category: Consumer Health News Source Type: news

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians.
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or aid clinicians to prognosticate patient risk. More than 250 biomarkers have been identified and evaluated over the last few decades, but no biomarker accurately differentiates between sepsis and sepsis-like syndrome. Published data support the use of biomarkers for pathogen identification, clinical diagnosis, and optimization of antibiotic treatment. In this narrative revi...
Source: Current Awareness Service for Health (CASH) - January 11, 2023 Category: Consumer Health News Source Type: news

The incidence and outcome of AKI in patients with sepsis in the emergency department applying different definitions of AKI and sepsis.
Conclusion The incidence of AKI in patients with sepsis is highly d ependent on how patients with sepsis are categorised and how AKI is defined. When AKI (any definition) was already present at the ED, 30-day mortality was high (22.2%). The diagnosis of AKI in sepsis can be considered as a sign of severe disease and helps to identify patients at high risk of adver se outcome at an early stage (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2023 Category: Consumer Health News Source Type: news

Comparison of the systematic Inflammatory response syndrome and the quick sequential organ failure assessment for prognostic accuracy in detecting sepsis in the emergency department: A systematic review.
Conclusion: The overall recommendation based on the included studies indicates that qSOFA is the better-suited screening tool for prognostic accuracy in detecting sepsis in the emergency department. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2023 Category: Consumer Health News Source Type: news

The experiences of sepsis in people with a learning disabilitya qualitative investigation.
Conclusion: Future research should be conducted with people with learning disabilities about their experiences shortl y after recovery from sepsis, to mitigate the effects of memory difficulties in recalling experiences. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2023 Category: Consumer Health News Source Type: news