Which occupations have the highest potential exposure to the coronavirus (COVID-19)?, ONS
This article uses an estimate of exposure to disease and physical proximity for different occupations to calculate which have the highest potential exposure to the coronavirus (COVID-19). Note these are based on survey results from before the pandemic, so will not take into account any recent changes in working practices. The article includes an interactive scatterplot that enables users to explore these data more fully and see how other occupations compare. It also looks at the demographics of those in these occupations (gender, age, ethnicity). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Accounting for the variation in the confirmed Covid-19 caseload across England: an analysis of multi-generation households, London and time, NPI
This paper develops a model that goes beyond correlation to measure the size of the impact of various socio-economic variables on the confirmed Covid-19 caseload. Alongside the proportion of over-70s who share a home with people of working-age, these variables include overcrowding and local area deprivation. It also draws out the policy questions raised by the model. Some of them relate to the policy response to the virus over the coming months. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Lifting lockdown: how to approach a coronavirus exit strategy , IFG
This report concludes that the government's five tests for starting to lift the lockdown are not a good enough guide to the longer-term exit strategy. It suggests that the government must instead set out new tests that explain how it will balance economic and health concerns against each other in lifting the restrictions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Preparing for the return to work outside the home: a trade union approach, TUC
This report sets out the TUC's recommendations for what the government should do now to ensure a safe transition from lockdown, looking at how to safely return to work outside the home, the enforcement measures needed to protect workers, and how best to protect workers'livelihoods. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Clinical characteristics and predictors of outcomes of hopsitalised patients with Covid-19 in a London NHS trust: a retrospective cohort study
This report is one of the first studies to describe the characteristics and predictors of outcomes for hospitalised Covid-19 patients in the UK. It finds that older age, male sex and admission hypoxia, thrombocytopenia, renal failure, hypoalbuminaemia and raised bilirubin are associated with increased odds of death. Ethnic minority groups were over-represented in the cohort and, compared to white people, people of black ethnicity may be at increased odds of mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19 review of national clinical practice guidelines for key questions relating to the care of pregnant women and their babies, Cochrane Pregnancy and Childbirth
Many clinicians and pregnant women with their families are facing similar questions about the care and wellbeing of women and their babies with confirmed or suspected Covid-19. We believe it is important to identify, collate and summarise national clinical practice guideline recommendations that address important questions. This would help busy clinicians, and pregnant women, to see quickly what other countries are recommending for key clinical questions and help inform their decisions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Can enhanced CBT help people with eating disorders during COVID-19?, The Mental Elf
Helen Bould summarises a guide for clinicians on how to deliver enhanced cognitive behavioural therapy (CBT-E) for people with eating disorders during COVID-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

New reagent available to support global diagnostic testing of coronavirus (COVID-19), MHRA
A new biological reagent is now available to labs around the UK and the world that will help them to set up and develop accurate diagnostic tests for coronavirus (COVID-19). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19: rapid tests for use in community pharmacies or at home, PHE (updated 11th May 2020)
Advice on the use of rapid point of care tests for COVID-19. Update in this version (published 11th May) - clarification that these are rapid point of care tests, different from those offered as part of testing for essential workers. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

National COVID-19 surveillance reports, PHE (updated 7th May 2020)
These reports summarise the surveillance activity of COVID-19 nationally.The summary report contains findings from systems within community, primary, secondary and mortality surveillance. It also includes an international update. Update in this version (published 7th May) - week 19 report added. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19: number of outbreaks in care homes management information, PHE (updated 7th May 2020)
This dataset shows the weekly number and percentage of care homes reporting a suspected or confirmed outbreak of COVID-19 to PHE by local authorities, regions and PHE centres. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19: background information, PHE (updated 8th May 2020)
Information on COVID-19 including epidemiology, virology and clinical features. Update in this version (published 8th May) - updated global case numbers. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Reducing risks from coronavirus transmission in the homethe role of viral load, BMJ
BMJ Analysis notes care is needed when extrapolating evidence from other diseases, but viral load is likely to be important for covid-19. It calls for better promotion of simple measures to help reduce spread and severity of infection among those living with people with covid-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Covid-19: the challenge of patient rehabilitation after intensive care, BMJ
As the first patients who have had the new virus and spent days ventilated in ICUs are discharged, the Chartered Society of Physiotherapy predicts a “tsunami of rehabilitation needs”. BMJ Feature questions whether appropriate rehabilitation will be available. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19: guidance for first responders, PHE (updated 9th May 2020)
This is advice for first responders (as defined by the Civil Contingencies Act) and others where close contact may be required as part of their normal duties. Update in this version (published 9th May) - removed references to Border Force and Immigration Enforcement Officers while further updates are in production. Update in version published 5th May: clarified sustained transmission in the community; specified use of PPE; added further advice on performing cardiopulmonary resuscitation and handling the deceased. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Number of coronavirus (COVID-19) cases and risk in the UK, DHSC/PHE (updated 10th May 2020)
As of 9am on 10th May, there have been 1,821,280 tests, with 92,837 tests on 9th May. 1,334,770 people have been tested, of which 219,183 tested positive. As of 5pm on 9th May, of those tested positive for coronavirus in the UK, 31,855 have died. This new figure includes deaths in all settings, not just in hospitals. The equivalent figure under the old measure would have been 26,568. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

COVID-19: staying at home and away from others (social distancing) guidance for young people, PHE
Information for young people on staying at home and away from others (known as social distancing). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 11, 2020 Category: Consumer Health News Source Type: news

Adapting stroke services during the COVID-19 pandemic: an implementation guide, British Association of Stroke Physicians
Guidance for adapting stroke services during the COVID-19 pandemic – and reshaping them afterwards – has been made available in a collaboration between the Getting It Right First Time (GIRFT) programme and the Oxford Academic Health Science Network (AHSN). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Restarting planned surgery in the context of the COVID-19 pandemic: A strategy document from the Royal College of Anaesthetists, Association of Anaesthetists, Intensive Care Society and Faculty of Intensive Care Medicine, FICM
As the UK and Ireland move beyond the current peak (or'surge') in the COVID-19 pandemic, national (state) health systems are looking to resume non-emergency and some elective surgery. Clinicians will rightly have concerns about what this means for their patients and for themselves. The ICM and anaesthesia COVID-19 collaborative in the UK has published a document describing when anaesthetic departments can start to move towards planned surgery, based on an assessment of their readiness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Guidance on shielding for Children and Adults with splenectomy or splenic dysfunction during the COVID-19 pandemic, BSH
This document aims to provide a clear and consistent summary of the recommendations as to which patients with splenectomy or functional asplenia should be classed as being at high risk of developing Covid-19-related complications and, as a consequence, be placed on the Shielded Patient List (SPL). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Tracking Public Health and Social Measures: A Global Dataset, WHO
Since the start of the COVID-19 pandemic, organizations began tracking implementation of Public health and social measures (PHSMs) around the world. A unique collaboration between WHO, the London School of Hygiene and Tropical Medicine, ACAPS, University of Oxford, Global Public Health Intelligence Network, US Centers for Disease Control and Prevention and the Complexity Science Hub Vienna has brought these datasets together into a single, open-content dataset for public use. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus (COVID-19) related deaths by ethnic group, England and Wales: 2 March 2020 to 10 April 2020
This provisional analysis has shown that the risk of death involving the coronavirus (COVID-19) among some ethnic groups is significantly higher than that of those of White ethnicity. When taking into account age in the analysis, Black males are 4.2 times more likely to die from a COVID-19-related death and Black females are 4.3 times more likely than White ethnicity males and females. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus and the social impacts on Great Britain: 7 May 2020
This weekly bulletin contains data and indicators from a new module being undertaken through the Office for National Statistics (ONS) Opinions and Lifestyle Survey (OPN) to understand the impact of the coronavirus (COVID-19) pandemic on British society. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

The potential impact of COVID-19 on mental health outcomes and the implications for service solutions
The evidence suggests that an increase in the prevalence of mental health conditions is likely during, and immediately after, the COVID-19 outbreak. However, amongst the general population, this increase subsided after quarantine measures are lifted. Healthcare workers are at greater risk of adverse mental health outcomes, particularly those who are frontline staff, who are in " high risk " units or have been re-deployed to " high risk units " from other departments. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus (COVID-19) infection control for care providers, SCIE (updated 6th May 2020)
Latest update 6th May This version has been updated to include the latest PPE guidance. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus Act 2020: status, DHSC
This table sets out the status of provisions in the 2 External 0 0 0 Coronavirus Act 2020 false http://www.legislation.gov.uk/ukpga/2020/7/contents/enacted true false%>. It covers the part of the act (Part 1) that facilitates legislative and regulatory changes that support the UK's response to the COVID-19 outbreak. 2 External 0 0 0 Further explanations about the purpose and effect of the act false https://services.parliament.uk/Bills/2019-21/coronavirus.html true false%> can be found on the relevant part of the UK Parliament website. The government also published 2 External 0 0 0 coronavirus action plan false http...
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Number of coronavirus (COVID-19) cases and risk in the UK, DHSC/PHE (updated 6th May 2020)
The latest number of coronavirus (COVID-19) cases and risk level in the UK. As of 9am 6 May, there have been 1,448,010 tests. There were 69,463 tests on 5 May. 1,072,144 people have been tested and 201,101 tested positive. As of 5pm on 5 May, of those who tested positive for coronavirus in the UK, 30,076 have died. This new figure includes deaths in all settings, not just in hospitals. The equivalent figure under the old measure would have been 25,148. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

SARS-CoV-2 and influenza virus co-infection, The Lancet
This report details four cases of SARS-CoV-2 and influenza co-infection. The clinical and analytical courses in these patients did not differ from those previously reported for COVID-19. However, more studies are needed to assess the clinical outcomes of co-infection. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

COVID-19: background information, PHE (updated 6 May 2020)
Information on COVID-19 including epidemiology, virology and clinical features.Update in this version (6 May 2020): updated global case numbers. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Acute limb ischaemia in two young, non-atherosclerotic patients with COVID-19, The Lancet
This paper reports a series of 4 patients with COVID-19 with acute limb ischaemia, and highlights that as young and healthy patients can develop severe vascular complications during SARS-CoV-2 infection, a prospective registry should be established to define treatment protocols. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

COVID-19: management of exposed healthcare workers and patients in healthcare settings, PHE (updated 6 May 2020)
This guidance covers staff exposures, staff return to work criteria and patient exposures.Update in this version (6 May 2020): updated title and content to provide clarification that the guidance applies to any healthcare setting, not just hospitals. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Global regulators work towards alignment on policy approaches and regulatory flexibility during COVID-19, EMA
In an international meeting, regulators have agreed to progress alignment on pre- and post-authorisation regulatory requirements to facilitate the rapid development, evaluation and availability of medicines for the treatment and prevention of coronavirus disease. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Occurrence, prevention, and management of the psychological effects of emerging virus outbreaks on healthcare workers: rapid review and meta-analysis
Effective interventions are available to help mitigate the psychological distress experienced by staff caring for patients in an emerging disease outbreak. These interventions were similar despite the wide range of settings and types of outbreaks covered in this review, and thus could be applicable to the current covid-19 outbreak. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers: A Living Rapid Review
Review of 64 studies found that depression, anxiety, and psychological distress were common in HCWs during the coronavirus disease 2019 outbreak. The strongest evidence on risk factors was on PPE use and decreased infection risk (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Valproate Pregnancy Prevention Programme: temporary advice for management during coronavirus (COVID-19) , MHRA
Owing to the COVID-19 pandemic and the reduced potential for face to face clinic appointments due to sheilding, the MHRA has made some temporary amendments to the pregnancy prevention programme for valproate products. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Factors that influence whether healthcare workers follow infection prevention and control guidelines for respiratory infectious diseases, Cochrane
The aim of this “qualitative evidence synthesis” is to explore factors that influence whether healthcare workers follow infection prevention and control (IPC) guidelines for respiratory infectious diseases. To answer this question, the authors searched for and analysed qualitative studies about this topic. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus (COVID-19): remote care through telehealth, Cochrane Special Collections
The aim of this collection is to ensure immediate access to systematic reviews most directly relevant to remote health care through telehealth. The measures adopted internationally to curb the spread of COVID-19 have led to significant changes in how health care is accessed and provided. As face-to-face consultations between healthcare workers and patients pose a potential risk to both parties, remote care and telehealth offer alternatives. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Covid-19 Guidance: Occupational Health and Staff Deployment, Faculty of Occupational Medicine (FOM)
The latest FOM guidance, co-authored by a number of senior occupational physicians, working across the NHS, public and private sector organisations. COVID-19 presents new risks for staff, patients and their contacts at home and work. Occupational Health (OH) advises about the interaction between health and work, aiming to protect staff from harm at work, maximise health and wellbeing and so contribute to safe patient care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Knock-on effects of coronavirus on access to healthcare: lived experience research, Traverse
As lockdown continues, we're starting to see data emerging about the knock-on effects of coronavirus on healthcare, from excess deaths reported in the FT, to concerns from Cancer Research about delayed diagnosis. Traverse interviewed a small sample of people whose healthcare had been disrupted to understand more about how the experience affected them. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Coronavirus (Covid-19): Information and advice, NMC
This guide tfrom the NMC address some common questions about their role as a regulator when it comes to novel coronavirus (Covid-19). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 7, 2020 Category: Consumer Health News Source Type: news

Failing the metric but saving lives: The protocolization of sepsis treatment through quality measurement
Quality metrics in the healthcare sector have become a key component of ensuring improved health outcomes and care equity. Alongside the emergence of information technology in healthcare (eg. electronic health records), the primary method utilized to infer " quality " has been the development of measures for healthcare processes and outcomes. Engaging with the specific case of sepsis treatment and sepsis quality metrics, this paper traces how quality is defined, measured, and codified in a 600-bed acute-care hospital in New York City. Sepsis is a severe health condition, primarily managed in the emergency departm...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

A survey of antibiotic administration practices involving patients with sepsis in UK critical care units
Conclusion Unlicensed alternative practices of antibiotic administration are widespread but only weak evidence exists of any patient benefit, such as reduced length of stay in critical care, and none showing improvement in mortality. Further research is needed to determine whether extended infusion methods offer clinically meaningful advantages over shorter licenced administration methods in patients in critical care units. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns
Conclusion(s): In addition to the well-known positive impact on antibiotic stewardship, implementation of the EOS calculator is also clearly associated with reductions in healthcare utilization related to suspected EOS in late preterm and term newborns and with a reduction in associated financial costs among those born term.What is Known:* The early-onset sepsis (EOS) calculator is a novel tool for antibiotic stewardship in newborns, associated with a reduction in empiric antibiotic treatment for suspected EOS.What is New:* In newborns at risk for EOS, EOS calculator implementation is associated with a significant reductio...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

New Medical Device Acquisition during Pediatric Severe Sepsis Hospitalizations
Objectives: Severe sepsis is a significant cause of healthcare utilization and morbidity among pediatric patients. However, little is known about how commonly survivors acquire new medical devices during pediatric severe sepsis hospitalization. We sought to determine the rate of new device acquisition (specifically, tracheostomy placement, gastrostomy tube placement, vascular access devices, ostomy procedures, and amputation) among children surviving hospitalizations with severe sepsis. For contextualization, we compare this to rates of new device acquisition among three comparison cohorts: 1) survivors of all-cause pediat...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Epigenetics of Sepsis
Conclusion(s): Epigenetic modifications are associated with key phases of sepsis, from the host-pathogen interaction, to acute inflammation, to immune suppression. Epigenetic markers show promise in the diagnosis and prognosis of sepsis and epigenetic modifying agents show promise as therapeutic tools in animal models of sepsis. Human studies in the area of epigenetics are sorely lacking and should be a priority for sepsis researchers. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Family integrated care in single family rooms for preterm infants and late-onset sepsis: a retrospective study and mediation analysis
Conclusion(s): SFRs were associated with decreased incidences of LOS and shorter length of hospital stay. The positive effect of SFRs on LOS was mainly mediated through a decreased use of PN in SFRs. Impact: Family integrated care (FICare) in single family rooms for preterm infants was associated with less late-onset sepsis events during hospital stay and a shorter length of hospital stay after birth.FICare in single family rooms was associated with less use of peripheral or central venous catheters and parenteral nutrition.Mediation analysis provided insights into the mechanisms underlying the effect of FICare in single f...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Pharmacokinetic and pharmacodynamic considerations in antimicrobial therapy for sepsis
Introduction: Antimicrobial dose optimization for the treatment of sepsis remains challenging because of dynamic pharmacokinetic alterations and physiological/pathological responses of the host. Subtherapeutic plasma levels of antimicrobials are commonly observed in patients with sepsis, which potentially leads to both treatment failure and emergence of antimicrobial resistance. The knowledge of antimicrobial pharmacokinetics and pharmacodynamics is helpful in order to tailor antimicrobial dosing strategies. Areas covered: This narrative review summarizes pharmacokinetic alterations of antimicrobial agents and provides use...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Prevalence ofAntibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use
Conclusions and Relevance: In this study, most patients with community-onset sepsis did not have resistant pathogens, yet broad-spectrum antibiotics were frequently administered. Both inadequate and unnecessarily broad empiric antibiotics were associated with higher mortality. These findings underscore the need for better tests to rapidly identify patients with resistant pathogens and for more judicious use of broad-spectrum antibiotics for empiric sepsis treatment. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report
Conclusion(s): When a newborn presents with non-specific symptoms of infection with an added history of COVID-19 in his/her parents, it indicates the need for PCR testing for Novel coronavirus. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news

Effect of Renin-Angiotensin-Aldosterone System Inhibitors on Short-Term Mortality after Sepsis:
Antagonists of the renin-angiotensin-aldosterone system (RAAS), including ACEIs (angiotensin-converting enzyme inhibitors) and ARBs (angiotensin II receptor blockers), may prevent organ failure. We, therefore, investigated whether specific RAAS inhibitors are associated with reduced mortality in patients with sepsis.We conducted a population-based retrospective cohort study using multivariable propensity score-based regression to control for differences among patients using different RAAS inhibitors. A multivariable-adjusted Cox proportional-hazards regression model was used to determine the association between RAAS inhibi...
Source: Current Awareness Service for Health (CASH) - May 6, 2020 Category: Consumer Health News Source Type: news