Homing in on free personal care
This report outlines the various reasons why free personal care can help provide the systemic change that social care needs. The report shows the scale of how many older people have had to sell their homes to pay for care, as well as how the current deferred payments system is not working. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Caring, supportive, collaborative: doctors' vision for change in the NHS
This report draws on the experience and expertise of BMA members across all branches of medical practice in the UK. It outlines where the BMA believes changes are needed to ensure patient care is safe, to make the NHS a great place to work and to transform services for the better. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Caring, supportive, collaborative: doctors' vision for change in the NHS
This report draws on the experience and expertise of BMA members across all branches of medical practice in the UK. It outlines where the BMA believes changes are needed to ensure patient care is safe, to make the NHS a great place to work and to transform services for the better. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Transforming care through technology a toolkit for new models of outpatient care
The emergence of new models of care using technology is a key theme of the work of the Shelford Group transformation directors. This toolkit outlines examples of how Shelford Group trusts are using technology and digital innovations to transform outpatient services in the NHS. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Contained or contagious? The future of infectious disease in ageing societies
This report urges policy-makers across the world to do more to adequately prepare for the growing risk of future pandemics. A number of global developments are currently increasing the likelihood of future outbreaks, including complacency around vaccination uptake, lack of awareness of the risks of infectious disease, antimicrobial resistance, climate change and global population migration. Moreover, in an ageing society, more of us are likely to be susceptible to infectious disease and experience complications resulting from disease. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Inclusive by default
This report finds a lack of skills, motivation and the right infrastructure are some of the key factors that make digital exclusion more likely. In addition to providing alternative routes for those unable to access digital public services, it is essential that these barriers are overcome. Designing accessible services, community support and partnerships across sectors are tools that can help to make digital public services inclusive by default. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Drug-related harms in homeless populations: government response
This document sets out the government's response to the Advisory Council on the Misuse of Drugs (ACMD) report on reducing drug-related harms in homeless populations. A letter from the Minister for Local Government and Homelessness to the ACMD is published on the government website. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Ageing and mobility: a grand challenge
This report provides analysis of evidence, experiences and insights gained from the Centre for Ageing Better's strategic partnership work in Greater Manchester and Leeds as well as wider stakeholder engagement. It is intended to spark innovation and collaboration, promote discussions between a wide variety of stakeholders, and help inform future research and activity. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Psychological perspectives on obesity: addressing policy, practice and research priorities
This report calls for the government to ensure every initiative aimed at promoting a healthy weight is informed by psychological evidence. It says weight management services are best delivered by multidisciplinary teams that include psychologists. All health professionals working in obesity services should be trained in the psychological understanding of obesity so they understand the factors that can contribute to the condition and to the success or failure of treatment. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Encouraging healthier'out of home' food provision: a toolkit for local councils working with small food businesses '
Public Health England (PHE) and its partners have developed this toolkit to support local councils and independent food businesses in helping children and families to choose healthier food. It is part of PHE's approach to dealing with obesity (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Encouraging healthier'out of home' food provision: a toolkit for local councils working with small food businesses '
Public Health England (PHE) and its partners have developed this toolkit to support local councils and independent food businesses in helping children and families to choose healthier food. It is part of PHE's approach to dealing with obesity (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Creating healthy lives: a whole-government approach to long-term investment in the nation's health
This publication makes the case for an ambitious, whole-government approach to long-term investment in the nation's health. It recommends five shifts in the government's overall approach to achieving this aim and outlines how investment can be rebalanced towards areas of spending that maintain and improve health, such as early years services, housing and social security. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

Creating healthy lives: a whole-government approach to long-term investment in the nation's health
This publication makes the case for an ambitious, whole-government approach to long-term investment in the nation's health. It recommends five shifts in the government's overall approach to achieving this aim and outlines how investment can be rebalanced towards areas of spending that maintain and improve health, such as early years services, housing and social security. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 1, 2019 Category: Consumer Health News Source Type: news

New Labour Guidance Resource for Women - Emma's Diary
The RCM has developed a new section in Emma's Diary Pregnancy Guide and Guide to Labour and Birth, with the aim of supporting conversations between midwives and the women in their care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 30, 2019 Category: Consumer Health News Source Type: news

New Labour Guidance Resource for Women - Emma's Diary
The RCM has developed a new section in Emma's Diary Pregnancy Guide and Guide to Labour and Birth, with the aim of supporting conversations between midwives and the women in their care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 30, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: C-reactive protein testing in general practice safely reduces antibiotic use for COPD flare-ups
Expert opinion is provided of a study which concludes rapid point-of-care CRP testing for patients presenting with an exacerbation of COPD may help with antibiotic stewardship, without compromising patient outcomes/safety, and the findings are likely to influence future guidance. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

Effect of measles vaccination in infants younger than 9 months on the immune response to subsequent measles vaccine doses: a systematic review and meta-analysis
Review reports first measles vaccines (MV) administered to infants (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

Integrated care: organisations, partnerships and systems
This report (September 2018) sets out how the recommendations will be addressed through the NHS Long Term Plan as well as summarising progress on integrated care so far and making recommendations for further development; (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

Digital transformation
This report aims to help public sector leaders understand how digital technologies, and the ways of working they enable, can help reform their organisations and deliver better public services. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

The financialisation of social care
This briefing paper examines social care's reliance on private bed provision and identifies three factors that can lead to lower quality care from private providers, especially those backed by private equity: workforce, instability and size. The report calls for the state to build and operate new residential care homes, and establish new financial regulator to oversee private providers. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

Chlorhexidine bathing of the critically ill for the prevention of hospitalacquired infection
Review (8 studies, n=24,472) states due to very low ‐certainty evidence available, it is not clear whether bathing with chlorhexidine reduces hospital‐acquired infections, mortality, or length of stay in the ICU, or whether use results in more skin reactions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 23, 2019 Category: Consumer Health News Source Type: news

Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption
Review (24 studies) reports changing number of available food options or altering the positioning of foods could contribute to meaningful changes in behaviour, justifying policy actions to promote such changes within food environments (based on low-very low quality evidence). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 23, 2019 Category: Consumer Health News Source Type: news

Prehospital characteristics among patients with sepsis: a comparison between patients with or without adverse outcome
The prehospital care of patients with sepsis are commonly performed by the emergency medical services. These patients may be critically ill and have high in-hospital mortality rates. Unfortunately, few patients with sepsis are identified by the emergency medical services, which can lead to delayed treatment and a worse prognosis. Therefore, early identification of patients with sepsis is important, and more information about the prehospital characteristics that can be used to identify these patients is needed. Based on this lack of information, the objectives of this study were to investigate the prehospital characteristic...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Regional trends in In-hospital Cardiac Arrest following sepsis-related admissions and subsequent mortality
Previous studies have reported regional variation in either the incidence or outcomes of sepsis or In-hospital Cardiac Arrest (IHCA) discretely; however, regional variations in the incidence and outcomes of sepsis-associated IHCA (SA-IHCA) have never been studied. This nationwide analysis demonstrates that the highest incidence of SA-IHCA is in the Southern region of the US whereas the associated in-hospital mortality was highest in the West. The incidence of SA-IHCA is rising in the Midwest and South from 2007 to 2014. Despite significant advances in the treatment of sepsis and IHCA, there has been no significant improvem...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Sepsis in patients with cirrhosis awaiting liver transplantation: new trends and management
Bacterial infections are more frequent and severe in patients with advanced liver disease and, therefore, in liver transplant candidates. The increased risk of infection in these patients parallels the severity of the immune dysfunction associated with cirrhosis, featured by systemic inflammation and progressive immunodeficiency. Other factors contribute to this risk, such as genetic polymorphisms, proton-pump inhibitor overuse, the numerous invasive procedures and hospitalizations these patients go through, or the immunosuppressive effects of malnutrition or alcohol abuse. Bacterial infections have a great impact on disea...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model
This article identifies the optimal target of anticoagulant therapy in sepsis. Anticoagulant therapy was associated with better outcome according to the deterioration of both DIC and disease severity, suggesting that anticoagulant therapy should be restricted to patients having DIC and high disease severity simultaneously. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Procalcitonin as a prognostic marker for sepsis based on SEPSIS-3
The objective of this study was to evaluate procalcitonin (PCT) for the diagnosis and prognosis of sepsis using SEPSIS-3. PCT could support and predict the unfavorable prognosis of sepsis based on SEPSIS-3, whereas diagnostic potential of PCT requires further evaluations. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Hypoxia and HIF activation as a possible link between sepsis and thrombosis
Risk factors for thrombosis include hypoxia and sepsis, but the mechanisms that control sepsis-induced thrombus formation are incompletely understood. A recent article published in Thrombosis Journal: (i) reviews the role of endothelial cells in the pathogenesis of sepsis-associated microthrombosis; (ii) describes a novel'two-path unifying theory'of hemostatic discorders; and (iii) refers to hypoxia as a consequence of microthrombus formation in sepsis patients. The current article adds to this review by describing how sepsis and thrombus formation could be linked through hypoxia and activation of hypoxia-inducible transcr...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Lactate Predicts Both Short- and Long-Term Mortality in Patients With and Without Sepsis
We report the novel finding that serum lactate, including normal values, is associated with long-term mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Incidence and impact of sepsis on long-term outcomes after subarachnoid hemorrhage: a prospective observational study
Aneurysmal subarachnoid hemorrhage (SAH) is an acute cerebrovascular disease associated with high mortality and long-term functional impairment among survivors. Systemic inflammatory responses after acute injury and nosocomial infections are frequent complications, making the management of these patients challenging. Here, we hypothesized that sepsis might be associated with early and long-term mortality and functional outcomes. Our objective was to define the incidence of sepsis, diagnosed prospectively with the Sepsis-3 criteria, and to determine its impact on mortality and functional outcomes of patients with SAH. Sepsi...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Overall systematic approach to sepsis damages on urogenital tissues: protective power of lacosamide
The aim of the study was to evaluate the harmful effects of sepsis on the urogynecological tissues and the ability of Lacosamide (LCM) on Lipopolysaccharide (LPS)-induced cytokine production, oxidative stress and apoptotic pathways, in the experimental rat sepsis model. These findings demonstrated that sepsis caused oxidative stress, apoptosis and inflammation in the urogenital tissues. We revealed that LCM ameliorated the damage caused by sepsis in urogenital tissue. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Sepsis information-seeking behaviors via Wikipedia between 2015 and 2018: A mixed methods retrospective observational study
Raising public awareness of sepsis, a potentially life-threatening dysregulated host response to infection, to hasten its recognition has become a major focus of physicians, investigators, and both non-governmental and governmental agencies. While the internet is a common means by which to seek out healthcare information, little is understood about patterns and drivers of these behaviors. We sought to examine traffic to Wikipedia, a popular and publicly available online encyclopedia, to better understand how, when, and why users access information about sepsis. Clickstream analysis suggests that most sepsis and septic shoc...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Comparison of the sepsis-2 and sepsis-3 definitions in severely injured trauma patients
To evaluate the performance of the new SOFA-based sepsis definition in trauma patients. The sepsis-3 definition identifies much fewer patients and is more strongly associated with adverse outcomes than the sepsis-2 definition. The sepsis-3 definition seems to be useful in the post trauma setting. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Impaired vascular reactivity in sepsis - a systematic review with meta-analysis
Vascular dysfunction due to reduced nitric oxide bioavailability plays an important role in the pathogenesis of sepsis. This meta-analysis examines evidence from published literature to evaluate whether in the adult population the presence/severity of sepsis is associated with impaired vasoreactivity. Septic patients have attenuated vascular reactivity when compared to healthy volunteers. There are insufficient data indicating that these changes can identify patients at risk of worsening organ failure or death. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Balanced Crystalloids Versus Saline in Sepsis: A Secondary Analysis of the SMART Trial
Administration of intravenous crystalloid solutions is a fundamental therapy for sepsis, but the effect of crystalloid composition on patient outcomes remains unknown. To compare the effect of balanced crystalloids versus saline on 30-day in-hospital mortality among critically ill adults with sepsis. Among patients with sepsis in a large randomized trial, use of balanced crystalloids was associated with a lower 30-day in-hospital mortality compared to use of saline (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news