Traumatic Brain Injury (TBI) Classification and Nomenclature Workshop
The National Institute of Neurological Disorders and Stroke (NINDS) is planning a Traumatic Brain Injury (TBI) Classification and Nomenclature Workshop to be held January 22 - 23, 2024, at the National Institutes of Health (NIH) in Bethesda, MD. Under the guidance of the Steering committee, six working groups have been developed; clinical experts and stakeholders in the TBI field have been invited to participate in these working groups. Working group members are currently meeting regularly working towards meeting their working group objectives. The workshop will be two-fold: 1) to highlight the working groups ’ findings ...
Source: Videocast - All Events - January 3, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

From Policies to pTau: Exposing Social and Structural Drivers of Alzheimer ’ s Disease and Opportunities for Brain Health Justice
Jennifer J. Manly, PhD is a Professor of Neuropsychology in Neurology at the Gertrude H. Sergievsky Center and the Taub Institute for Research in Aging and Alzheimer ’ s disease at Columbia University. Her research focuses on mechanisms of inequalities in cognitive aging and Alzheimer ’ s Disease. Her research team has partnered with the Black and Latinx communities in New York City and around the United States to design and carry out investigations of structural and social forces across the lifecourse, such as educational opportunities, discrimination, and socioeconomic inequality, and how these factors relate to cogn...
Source: Videocast - All Events - January 3, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH BRAIN Initiative Multi-Council Working Group Meeting
The purpose of the meeting is to receive feedback and guidance on funding opportunity announcements, incoming applications, and strategic planning for the NIH component of the BRAIN Initiative. The MCWG is comprised of 10 representatives from the 10 participating BRAIN Institutes/Centers (including NINDS), 5 at-large members, and ex officio representatives from the other participating federal agencies. The meeting will also provide an opportunity for private entities/foundations to present their contributions to BRAIN. The meeting will provide the neuroethics workgroup of the MCWG, comprised of MCWG members, federal staff,...
Source: Videocast - All Events - December 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH BRAIN Neuroethics Working Group Meeting
The purpose of the meeting is to receive feedback and guidance on funding opportunity announcements, incoming applications, and strategic planning for the NIH component of the BRAIN Initiative. The MCWG is comprised of 10 representatives from the 10 participating BRAIN Institutes/Centers (including NINDS), 5 at-large members, and ex officio representatives from the other participating federal agencies. The meeting will also provide an opportunity for private entities/foundations to present their contributions to BRAIN. The meeting will provide the neuroethics workgroup of the MCWG, comprised of MCWG members, federal staff,...
Source: Videocast - All Events - December 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

WALS: The Structure and Mechanism of Cell Surface Signaling Complexes
Yvonne Jones is co-Head of STRUBI and Deputy Head of the NDM. Her own research group is focused on the structural biology of extracellular recognition and signaling complexes. The group's core techniques include protein crystallography and cryo electron microscopy, which are used to generate high resolution structural information. Importantly, studies using these techniques are integrated with advanced light microscopy and cryo electron tomography, as well as cell-based functional studies, to probe molecular mechanisms at the cell surface. The group's research addresses fundamental questions about cell-cell signaling syste...
Source: Videocast - All Events - December 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Demystifying Medicine — Cognitive Loss, Dementia, and Neurodegenerative Disorders: Vascular and Genetic Factors
The Demystifying Medicine Series, jointly sponsored by FAES and NIH, includes presentations on pathology, diagnosis, and therapy in the context of major disease problems and current research. Primarily directed toward PhD students, clinicians and program managers, this series is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. All students, trainees, fellows, and staff are welcome to participate.For more information go tohttps://demystifyingmedicine.od.nih.govAir date: 4...
Source: Videocast - All Events - December 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

WALS Lecture: Leveraging Genetics and Cell Signaling to Decipher Disorders of Excitability
Presentation Objectives: To understand how genetic testing illuminates the causes of a devastating disease, Sudden Unexpected Death in Childhood, and identifies dysfunctional calcium signaling as a major cause; To chart a course for how genetic analysis of neuropsychiatric disorders such as schizophrenia, Major Depressive Disorder and Bipolar Disorder will spur understanding the impact of non-coding variations in key signaling proteins; To appreciate how genetics highlights underappreciated signaling molecules that coordinate excitatory and inhibitory synaptic strength and provide a target for cannabidiol (CBD) action in e...
Source: Videocast - All Events - December 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH ProtIG Seminar: The role of long-lived proteins in aging and Alzheimer ’ s disease
Loss of proteostasis is a hallmark of aging, and aging is the greatest risk factor for Alzheimer's disease (AD). Deterioration in function and accumulation of damage to the proteome are largely repaired by protein turnover. These turnover mechanisms are particularly important in long-lived postmitotic neurons, which cannot dilute toxic proteins through cell division. We aimed to identify extremely long-lived proteins (ELLP) that persist for several months or longer across the aging continuum in wild-type mice and in genetic AD mouse models. We hypothesize that these ELLPs represent key points of vulnerability to the declin...
Source: Videocast - All Events - November 30, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Ellen Leibenluft: Celebrating a Career in Understanding the Brain Mechanisms of Irritability in Youth
This event celebrates the research inspired by the work of a leading NIMH scientist, Dr. Ellen Leibenluft. A series of talks describe research on mental illnesses in children and adolescents. These talks highlight facets of mental illnesses that involve disruptions in emotional processes. They focus on clinical presentation, longitudinal outcome, treatment and neurobiology, in talks from Dr. Leibenluft's colleagues, from around the world.Air date: 1/11/2024 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - November 29, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Sensing Inflammation in the Skin and Beyond
The type 2 immune response has evolved to arm the mammalian host with the capacity to expel parasites and noxious environmental substances from barrier surfaces. One critical aspect of this defense mechanism is stimulating protective behavioral responses such as coughing, sneezing, and scratching. Increasingly, it is appreciated that cytokines associated with type 2 immunity such as IL-4, IL-13, and IL-31 play critical roles in triggering mechanical reflexes like itch via direct interactions with sensory neurons. However, the tissue- and cell-specific manner in which these cytokines imprint unique sensory and neuroinflamma...
Source: Videocast - All Events - November 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NICHD Interview Seminar: Dr. Neal Amin
Dr. Neal Amin, an NICHD tenure-track investigator candidate, will give a seminar on " Deconvoluting RNA processing networks affecting human neurodevelopment and disease. "Air date: 12/13/2023 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - November 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NICHD Interview Chalk Talk: Dr. Neal Amin
Dr. Neal Amin, an NICHD tenure-track investigator candidate, will give a chalk talk on his plans to establish a lab to profile, decode, and modulate disease-associated RNA processing events towards the larger goal of identifying principles of human neural gene network regulation, mechanisms of dysregulation in disease, and new pharmacological targets for a range of neuropsychiatric conditions.Air date: 12/13/2023 1:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Brain sex differences are specified by gonadal hormone receptors
This seminar is part of the NIH Neuroscience Seminar Series which is supported by all the NIH Institues and Centers that have Neuroscience Labs.Air date: 1/29/2024 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 16, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Combining human genetics with physiology to understand the mechanisms of persistent pain
This seminar is part of the NIH Neuroscience Seminar Series supported by the Scientific Directors of every Institute or Center that has Neuroscience Labs at the NIH.Air date: 1/22/2024 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 15, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Director's Seminar Series: Neural mechanisms of human episodic memory formation
Memory is critical to our everyday experience. We rely upon our memories not only to form our own sense of identity, but also to guide and plan our future actions and behaviors. Understanding the neural mechanisms that underlie human memory formation is therefore critical in order to effectively treat memory disorders which are present in some of the most debilitating yet poorly managed neurological diseases. Our research efforts are focused on investigating the neural correlates of human episodic memory formation by leveraging the opportunities to directly record neural activity across multiple spatial scales from the hum...
Source: Videocast - All Events - November 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video