Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Update of triggers for detection of adverse drug events in hematologic patients
This study demonstrated the importance of an updated list of triggers for the monitoring of ADEs and improvement of the care provided.PMID:38126560 | PMC:PMC10740396 | DOI:10.1590/0102-311XPT077923 (Source: Cadernos de Saude Publica)
Source: Cadernos de Saude Publica - December 21, 2023 Category: International Medicine & Public Health Authors: Íris Pilegi Domingues Milene Rangel da Costa Source Type: research

Sweet Syndrome: Clinical Presentation, Malignancy Association, Autoinflammatory Disorders and Treatment Response in a Cohort of 93 Patients with Long-term Follow-up
Acta Derm Venereol. 2023 Dec 19;103:adv18284. doi: 10.2340/actadv.v103.18284.ABSTRACTSweet syndrome is a neutrophilic dermatosis associated with multiple disorders. This retrospective case-series study of patients with Sweet syndrome in a tertiary hospital in Spain from 2001 to 2021, explores clinicopathological characteristics of Sweet syndrome and variables associated with malignancy, presence of autoinflammatory disorders and differences between histological subtypes. A total of 93 patients were identified: 30% idiopathic, 34% malignancy-associated, 29% reactive to infections or drug-associated, and 6% with an autoimmun...
Source: Acta Dermato-Venereologica - December 19, 2023 Category: Dermatology Authors: Javier Gil-Lianes Mar Luque-Luna Francesc Alamon-Reig Xavier Bosch-Amate Laura Serra-Garcia Jos é M Mascaró Source Type: research

Sweet Syndrome: Clinical Presentation, Malignancy Association, Autoinflammatory Disorders and Treatment Response in a Cohort of 93 Patients with Long-term Follow-up
Acta Derm Venereol. 2023 Dec 19;103:adv18284. doi: 10.2340/actadv.v103.18284.ABSTRACTSweet syndrome is a neutrophilic dermatosis associated with multiple disorders. This retrospective case-series study of patients with Sweet syndrome in a tertiary hospital in Spain from 2001 to 2021, explores clinicopathological characteristics of Sweet syndrome and variables associated with malignancy, presence of autoinflammatory disorders and differences between histological subtypes. A total of 93 patients were identified: 30% idiopathic, 34% malignancy-associated, 29% reactive to infections or drug-associated, and 6% with an autoimmun...
Source: Acta Derm Venereol A... - December 19, 2023 Category: Dermatology Authors: Javier Gil-Lianes Mar Luque-Luna Francesc Alamon-Reig Xavier Bosch-Amate Laura Serra-Garcia Jos é M Mascaró Source Type: research

Sweet Syndrome: Clinical Presentation, Malignancy Association, Autoinflammatory Disorders and Treatment Response in a Cohort of 93 Patients with Long-term Follow-up
Acta Derm Venereol. 2023 Dec 19;103:adv18284. doi: 10.2340/actadv.v103.18284.ABSTRACTSweet syndrome is a neutrophilic dermatosis associated with multiple disorders. This retrospective case-series study of patients with Sweet syndrome in a tertiary hospital in Spain from 2001 to 2021, explores clinicopathological characteristics of Sweet syndrome and variables associated with malignancy, presence of autoinflammatory disorders and differences between histological subtypes. A total of 93 patients were identified: 30% idiopathic, 34% malignancy-associated, 29% reactive to infections or drug-associated, and 6% with an autoimmun...
Source: Acta Derm Venereol A... - December 19, 2023 Category: Dermatology Authors: Javier Gil-Lianes Mar Luque-Luna Francesc Alamon-Reig Xavier Bosch-Amate Laura Serra-Garcia Jos é M Mascaró Source Type: research

Sweet Syndrome: Clinical Presentation, Malignancy Association, Autoinflammatory Disorders and Treatment Response in a Cohort of 93 Patients with Long-term Follow-up
Acta Derm Venereol. 2023 Dec 19;103:adv18284. doi: 10.2340/actadv.v103.18284.ABSTRACTSweet syndrome is a neutrophilic dermatosis associated with multiple disorders. This retrospective case-series study of patients with Sweet syndrome in a tertiary hospital in Spain from 2001 to 2021, explores clinicopathological characteristics of Sweet syndrome and variables associated with malignancy, presence of autoinflammatory disorders and differences between histological subtypes. A total of 93 patients were identified: 30% idiopathic, 34% malignancy-associated, 29% reactive to infections or drug-associated, and 6% with an autoimmun...
Source: Acta Dermato-Venereologica - December 19, 2023 Category: Dermatology Authors: Javier Gil-Lianes Mar Luque-Luna Francesc Alamon-Reig Xavier Bosch-Amate Laura Serra-Garcia Jos é M Mascaró Source Type: research

Aggregation of human plasma and of human blood induced in vitro by filgrastim originator product; effect of PEGylation
Eur J Pharm Biopharm. 2023 Dec 12:S0939-6411(23)00328-4. doi: 10.1016/j.ejpb.2023.12.004. Online ahead of print.ABSTRACTWe herein report that filgrastim product Neupogen® and the filgrastim formulation buffer induced aggregate formation when mixed in vitro with human plasma, and formation of large membranous erythrocyte aggregates when mixed with human blood, similar to the aggregation induced by pegfilgrastim and by pegfilgrastim buffer [T. Arvinte, E. Poirier, N. Ersayin, G. Darpin, A. Cudd, J. Dowd, S. Brokx, Aggregation of human plasma and of human blood induced in vitro by pegfilgrastim originator formulation buffer ...
Source: European Journal of Pharmaceutics and Biopharmaceutics - December 14, 2023 Category: Drugs & Pharmacology Authors: Tudor Arvinte Emilie Poirier Amelia Cudd Nuri Ersayin Guillaume Darpin Jason Dowd Stephen Brokx Source Type: research

Aggregation of human plasma and of human blood induced in vitro by filgrastim originator product; effect of PEGylation
Eur J Pharm Biopharm. 2023 Dec 12:S0939-6411(23)00328-4. doi: 10.1016/j.ejpb.2023.12.004. Online ahead of print.ABSTRACTWe herein report that filgrastim product Neupogen® and the filgrastim formulation buffer induced aggregate formation when mixed in vitro with human plasma, and formation of large membranous erythrocyte aggregates when mixed with human blood, similar to the aggregation induced by pegfilgrastim and by pegfilgrastim buffer [T. Arvinte, E. Poirier, N. Ersayin, G. Darpin, A. Cudd, J. Dowd, S. Brokx, Aggregation of human plasma and of human blood induced in vitro by pegfilgrastim originator formulation buffer ...
Source: European Journal of Pharmaceutics and Biopharmaceutics - December 14, 2023 Category: Drugs & Pharmacology Authors: Tudor Arvinte Emilie Poirier Amelia Cudd Nuri Ersayin Guillaume Darpin Jason Dowd Stephen Brokx Source Type: research

Motixafortide: First Approval
This article summarizes the milestones in the development of motixafortide leading to this first approval. (Source: Drugs)
Source: Drugs - November 23, 2023 Category: Drugs & Pharmacology Source Type: research

The Impact of Biosimilar Use on Total Cost of Care and Provider Financial Performance in the Medicare Oncology Care Model: A Population-Based Simulation Study
CONCLUSIONS: On the basis of our simulation study using observed Medicare claims and OCM criteria, we found that biosimilar substitution for reference products can significantly lower episode TCOC and improve provider financial performance under the terms of the largest value-based payment model implemented to date.PMID:37957523 | DOI:10.1007/s12325-023-02703-x (Source: Adv Data)
Source: Adv Data - November 13, 2023 Category: Epidemiology Authors: Jingyan Yang Basit I Chaudhry Andrew T Yue Joshua A Roth John M Kelton Ahmed Shelbaya Lisa Tran Meng Li Source Type: research