Parenchymal obliteration by renal masses: Functional and oncologic implications
CONCLUSIONS: Obliteration of normal parenchyma by RCC substantially impacts preoperative renal function and patient selection. Our data suggests that increased PVR is primarily driven by aggressive tumor characteristics and independently associates with reduced RFS, although further studies will be needed to substantiate our findings.PMID:38729867 | DOI:10.1016/j.urolonc.2024.04.019 (Source: Urologic Oncology)
Source: Urologic Oncology - May 10, 2024 Category: Urology & Nephrology Authors: Akira Kazama Carlos Munoz-Lopez Worapat Attawettayanon Melissa Boumitri Eran Maina Zaeem Lone Nityam Rathi Kieran Lewis Rebecca A Campbell Diego Aguilar Palacios Jihad Kaouk Georges-Pascal Haber Samuel Haywood Nima Almassi Christopher J Weight Erick M Rem Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Parenchymal obliteration by renal masses: Functional and oncologic implications
CONCLUSIONS: Obliteration of normal parenchyma by RCC substantially impacts preoperative renal function and patient selection. Our data suggests that increased PVR is primarily driven by aggressive tumor characteristics and independently associates with reduced RFS, although further studies will be needed to substantiate our findings.PMID:38729867 | DOI:10.1016/j.urolonc.2024.04.019 (Source: Urologic Oncology)
Source: Urologic Oncology - May 10, 2024 Category: Urology & Nephrology Authors: Akira Kazama Carlos Munoz-Lopez Worapat Attawettayanon Melissa Boumitri Eran Maina Zaeem Lone Nityam Rathi Kieran Lewis Rebecca A Campbell Diego Aguilar Palacios Jihad Kaouk Georges-Pascal Haber Samuel Haywood Nima Almassi Christopher J Weight Erick M Rem Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Parenchymal obliteration by renal masses: Functional and oncologic implications
CONCLUSIONS: Obliteration of normal parenchyma by RCC substantially impacts preoperative renal function and patient selection. Our data suggests that increased PVR is primarily driven by aggressive tumor characteristics and independently associates with reduced RFS, although further studies will be needed to substantiate our findings.PMID:38729867 | DOI:10.1016/j.urolonc.2024.04.019 (Source: Urologic Oncology)
Source: Urologic Oncology - May 10, 2024 Category: Urology & Nephrology Authors: Akira Kazama Carlos Munoz-Lopez Worapat Attawettayanon Melissa Boumitri Eran Maina Zaeem Lone Nityam Rathi Kieran Lewis Rebecca A Campbell Diego Aguilar Palacios Jihad Kaouk Georges-Pascal Haber Samuel Haywood Nima Almassi Christopher J Weight Erick M Rem Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research

Giant Renal Angiomyolipomas and Pulmonary Lymphangioleiomyomatosis: Follow-up Report after More than a Decade
Saudi J Kidney Dis Transpl. 2023 Nov 1;34(6):671-675. doi: 10.4103/sjkdt.sjkdt_324_21. Epub 2024 May 9.ABSTRACTRenal angiomyolipomas (AMLs) and pulmonary lymphangioleiomyomatosis (LAM) are two major presentations of tuberous sclerosis (TS), an autosomal dominant multisystem disorder. Renal AMLs can lead to life-threatening complications like hemorrhage and cause progressive renal failure requiring dialysis and kidney transplant. mTOR inhibitors showed promising results in TS patients with renal AMLs, LAM, and subependymal giant cell astrocytomas. This case report is a follow-up of a patient we reported in 2010 with giant A...
Source: Saudi Journal of Kidney Diseases and Transplantation - May 10, 2024 Category: Urology & Nephrology Authors: Kiran Nasir Aasim Ahmad Source Type: research