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Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results. Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

New Research Which Could Have More Thought
This study did not include women who had mastectomies or suspicious or enlarged lymph nodes in a physical exam." To make sure that women have the appropriate lymph node surgery, the American Society for Clinical Oncology released guidelines on sentinel lymph node biopsy for people diagnosed with early-stage breast cancer. The guidelines say sentinel lymph node biopsy SHOULD be offered under these circumstances:breast cancer in which there is more than one tumor, all of which have formed separately from one another (doctors call these multicentric tumors); these types of breast cancers are rareDCIS treated with mastectomywo...
Source: Caroline's Breast Cancer Blog - October 8, 2017 Category: Cancer & Oncology Tags: breast cancer breast cancer treatment young cancer patients Source Type: blogs

An Interview with Orthopaedic Oncologist Dr. Vincent Ng
Dr. Vincent Ng is an orthopaedic oncologist with the University of Maryland Greenebaum Comprehensive Cancer Center and an Assistant Professor or Orthopaedics with the University of Maryland School of Medicine. Dr. Ng specializes in treating bone cancer and soft tissue sarcoma. Below he answers common questions about orthopaedic oncology. What is an orthopaedic oncologist? How do they differ from surgical oncologists? “An orthopaedic oncologist specializes in bone and soft tissue tumors. I treat any adult or pediatric patient with any bone or soft tissue tumor/lesion/mass, whether benign or malignant, whether it is...
Source: Life in a Medical Center - June 2, 2017 Category: Universities & Medical Training Authors: UMMC Tags: Cancer Doctors bone cancer oncology orthopedics Source Type: blogs

Carcinoma Rectum :MRI
Discussion by Dr MGK Murthy, Dr GA PrasadMR- useful to assist staging & identify patients who may benefit from preoperative chemotherapy–radiation therapy, and in surgical planning.Currently, surgical resection with stage-appropriate neoadjuvant combined-modality therapy is the mainstay in the treatment of rectal cancer.Total mesorectal excision (TME) has reduced the prevalence of local recurrence from 38% to less than 10%. TME is surgical en bloc resection of the primary tumor and the mesorec tum by means of dissection along the mesorectal fascial plane or the circumferential resection margi...
Source: Sumer's Radiology Site - April 28, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

In An Era Of Bold New Cancer Treatments An Older Drug Shows Real Promise For Advanced Prostate Cancer
The annual meeting of the American Society of Clinical Oncology here in Chicago is a place where many commercial interests jostle for attention to make their latest promising therapy the star of the show. But this weekend, a standard widely available generic drug stole the show by producing incredible results in improving survival for men with advanced prostate cancer. And that has some of us asking, "Why did it take so long to find out? The drug is docetaxel, which for decades has been used to treat a number of cancers, including prostate cancers. We have known for some time that it is helpful in the treatment of men who...
Source: Dr. Len's Cancer Blog - June 2, 2014 Category: Cancer Authors: Dr. Len Tags: Cancer Care Medications Prostate Cancer Treatment Source Type: blogs

New nanopharmaceutical may help overcome resistance to specific anticancer drugs
Conclusions: Results generated through this translational research plan suggest that CRLX101 can overcome HIF-1α-mediated acquired resistance to antiangiogenic drugs, assisting the use of CRLX101 in combination with antiangiogenic medicines as an exciting new paradigm for the treatment of cancer. Related Posts:Cleveland Clinic’s preventive breast cancer vaccine…Harvard Stem Cell Institute publishes initial clinical trialImportant advance in the fight against skin cancerNew IBS treatment shows possible in Phase 2 researchNew blood test could help millions of patients with&hellip...
Source: My Irritable Bowel Syndrome Story - October 21, 2013 Category: Other Conditions Authors: Ken Tags: IBS News Source Type: blogs