Cushing's syndrome with inhaled corticosteroid: Drug interactions to avoid
We report the clinical case of a 29-year-old woman with a past history of asthma treated with inhaled fluticasone propionate (FP), chronic pulmonary aspergillosis and allergic bronchopulmonary aspergillosis (ABPA) treated with itraconazole (ITZ), and Mycobacterium xenopi infection treated with moxifloxacin (MXF), ethambutol (EMB) and clarithromycin (CLR). Four months after initiation of antibiotic and antifungal medication, the patient contracted Cushing's syndrome. Its etiology consisted in interaction between FP, ITZ and CLR, which led to pronouncedly increased corticosteroid concentrations in circulating plasma cells. F...
Source: Revue des Maladies Respiratoires - September 24, 2023 Category: Respiratory Medicine Authors: M Briard C Godet D Mouren G Weisenburger H Mal J Messika M Salpin T Goletto V Bunel M Veyrier Source Type: research
Mycoplasma genitalium
(MG) is an emerging sexually transmitted infection, which appears to be a cause of urethritis and cervicitis and has been associated with pelvic inflammatory disease (PID), epididymitis, proctitis, infertility, complications during pregnancy, and human immunodeficiency virus (HIV) transmission. Three Food and Drug Administration (FDA) approved tests are available. Testing should be focused to avoid inappropriate antibiotic use. The Center of Disease Control and Prevention (CDC) guidelines recommend testing for persistent male urethritis, cervicitis, and proctitis and state that testing should be considered in cases of PID...
Source: Medical Clinics of North America - September 13, 2023 Category: Primary Care Authors: Oluyomi A. Obafemi, Sarah E. Rowan, Masayo Nishiyama, Karen A. Wendel Source Type: research
Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces < em > Staphylococcus aureus < /em > infection and reduces < em > Escherichia coli < /em > infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model
In this study, we examined the efficacy of oral treatment with NCL195 (± low-dose colistin) in comparison to oral moxifloxacin in bioluminescent Staphylococcus aureus and Escherichia coli peritonitis-sepsis models. Four oral doses of 50 mg/kg NCL195, commencing immediately post-infection, were administered at 4 h intervals in the S. aureus peritonitis-sepsis model. We used a combination of four oral doses of 50 mg/kg NCL195 and four intraperitoneal doses of colistin at 0.125 mg/kg, 0.25 mg/kg, or 0.5 mg/kg in the E. coli peritonitis-sepsis model. Subsequently, the dose rates of four intraperitoneal doses of colistin were ...
Source: Antimicrobial Agents and Chemotherapy - September 11, 2023 Category: Microbiology Authors: Hang Thi Nguyen Henrietta Venter Lucy Woolford Kelly A Young Adam McCluskey Sanjay Garg Sylvia S Sapula Stephen W Page Abiodun David Ogunniyi Darren J Trott Source Type: research
Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces < em > Staphylococcus aureus < /em > infection and reduces < em > Escherichia coli < /em > infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model
In this study, we examined the efficacy of oral treatment with NCL195 (± low-dose colistin) in comparison to oral moxifloxacin in bioluminescent Staphylococcus aureus and Escherichia coli peritonitis-sepsis models. Four oral doses of 50 mg/kg NCL195, commencing immediately post-infection, were administered at 4 h intervals in the S. aureus peritonitis-sepsis model. We used a combination of four oral doses of 50 mg/kg NCL195 and four intraperitoneal doses of colistin at 0.125 mg/kg, 0.25 mg/kg, or 0.5 mg/kg in the E. coli peritonitis-sepsis model. Subsequently, the dose rates of four intraperitoneal doses of colistin were ...
Source: Antimicrobial Agents and Chemotherapy - September 11, 2023 Category: Microbiology Authors: Hang Thi Nguyen Henrietta Venter Lucy Woolford Kelly A Young Adam McCluskey Sanjay Garg Sylvia S Sapula Stephen W Page Abiodun David Ogunniyi Darren J Trott Source Type: research
Genetic surveillance and outcomes of pyrazinamide and fluoroquinolones-resistant tuberculosis in Taiwan
CONCLUSION: We concluded that routine PZA and FQ susceptibility tests are recommended for guiding the treatment of TB.PMID:37690869 | DOI:10.1016/j.jmii.2023.08.013 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 10, 2023 Category: Microbiology Authors: Hsin-Ting Huang Wan-Hsuan Lin Tai-Hua Chan Ruwen Jou Source Type: research
Genetic surveillance and outcomes of pyrazinamide and fluoroquinolones-resistant tuberculosis in Taiwan
CONCLUSION: We concluded that routine PZA and FQ susceptibility tests are recommended for guiding the treatment of TB.PMID:37690869 | DOI:10.1016/j.jmii.2023.08.013 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 10, 2023 Category: Microbiology Authors: Hsin-Ting Huang Wan-Hsuan Lin Tai-Hua Chan Ruwen Jou Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | DOI:10.3346/jkms.2023.38.e278 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - September 5, 2023 Category: Biomedical Science Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | DOI:10.3346/jkms.2023.38.e278 (Source: J Korean Med Sci)
Source: J Korean Med Sci - September 5, 2023 Category: General Medicine Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - September 5, 2023 Category: Biomedical Science Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: J Korean Med Sci)
Source: J Korean Med Sci - September 5, 2023 Category: General Medicine Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - September 5, 2023 Category: Biomedical Science Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: J Korean Med Sci)
Source: J Korean Med Sci - September 5, 2023 Category: General Medicine Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - September 5, 2023 Category: Biomedical Science Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: J Korean Med Sci)
Source: J Korean Med Sci - September 5, 2023 Category: General Medicine Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
Developing Operational Definitions Related to < em > Helicobacter pylori < /em > Eradication Therapy
CONCLUSION: We developed and validated operational definitions related to H. pylori eradication therapy. These definitions will help researchers perform various H. pylori eradication-related studies using secondary databases.PMID:37667583 | PMC:PMC10477078 | DOI:10.3346/jkms.2023.38.e278 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - September 5, 2023 Category: Biomedical Science Authors: Chan Hyuk Park Sun-Young Jung Ju Won Lee Hyo-Joon Yang Joon Sung Kim Beom Jin Kim Soo In Choi Seung In Seo Joongyub Lee Jae Gyu Kim Korean Research Association for Helicobacter and Microbiome Source Type: research
