Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL
Conditions: Lymphoblastic Leukemia; Philadelphia-Positive ALL; Adult ALL Interventions: Drug: Vincristine; Drug: Dexamethasone; Drug: Imatinib; Drug: Cytarabine; Drug: Mercaptopurine; Drug: Methotrexate; Drug: Ponatinib; Procedure: allogeneic stem cell transplantation; Procedure: Total body irradiation; Drug: Cyclophosphamide; Drug: Fludarabine Sponsors: PETHEMA Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 19, 2023 Category: Research Source Type: clinical trials
Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis
Conditions: Nail Psoriasis Interventions: Device: Excimer laser; Drug: Methotrexate Injection Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 29, 2023 Category: Research Source Type: clinical trials
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Procedure: Biospecimen Collection; Procedure: Chest Computed Tomography; Procedure: Echocardiography; Procedure: Hematopoietic Cell Transplantation; Drug: Methotrexate; Procedure: Multigated Acquisition Scan; Drug: Ruxolitinib Phosphate; Drug: Tacrolimus Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Conditions: B Acute Lymphoblastic Leukemia Interventions: Procedure: Biospecimen Collection; Biological: Blinatumomab; Procedure: Bone Marrow Biopsy; Drug: Calaspargase Pegol; Drug: Cyclophosphamide; Drug: Cytarabine; Drug: Dasatinib; Drug: Daunorubicin; Drug: Doxorubicin; Procedure: Echocardiography; Drug: Leucovorin; Drug: Mercaptopurine; Drug: Methotrexate; Procedure: Multigated Acquisition Scan; Drug: Pegaspargase; Drug: Prednisolone; Drug: Prednisone; Radiation: Radiation Therapy; Drug: Thioguanine; Drug: Vincristine Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 9, 2023 Category: Research Source Type: clinical trials
Evaluation of High Dose Methotrexate Toxicity
Conditions: Methotrexate Toxicity Interventions: Diagnostic Test: blood methotrexate level and Cystatin C level Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials
A Retrospective Study of Newly-diagnosed PCNSL Treated With a Methotrexate (MTX) and Orelabrutinib-based Regimen
Conditions: Primary Central Nervous System Lymphoma Interventions: Drug: Orelabrutinib Sponsors: Huashan Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 3, 2023 Category: Research Source Type: clinical trials
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects
Conditions: Drug Interactions Interventions: Drug: Methotrexate Sodium; Drug: Rifampicin Sponsors: Seoul National University Bundang Hospital Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials
Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children
Conditions: Lymphoblastic Leukemia in Children Interventions: Drug: induction: vincristine, L-asparaginase, dexamethasone, intrathecal Ara-C, intrathecal Methotrexate; Drug: Consolidation: Vincristine, Mecaptopurine, Intrathecal Methotrexate; Drug: Consolidation: Vincristine, Mecaptopurine, Cyclophosphamide, Cytarabine, L-asparaginase, Intrathecal Methotrexate; Drug: Interim Maintenance(IM): Vincristine, Methotrexate, Intrathecal Methotrexate; Drug: Interim Maintenance(IM): Vincristine, Methotrexate, Mercaptopurine, Intrathecal Methotrexate; Drug: Delayed Intesification(DI): Vincristine, Mercaptopurine, L-asparaginase, Dox...
Source: ClinicalTrials.gov - October 25, 2023 Category: Research Source Type: clinical trials
Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata
Conditions: Alopecia Areata Interventions: Drug: Methotrexate; Drug: Triamcinolone Acetonide Sponsors: Al-Azhar University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 18, 2023 Category: Research Source Type: clinical trials
BRE-08: A Phase II Study of an All-Oral Adjuvant Chemotherapy Regimen of Cyclophosphamide, Methotrexate, and Capecitabine (CMC) for Early-Stage Breast Cancer
Conditions: Breast Cancer Interventions: Drug: Cyclophosphamide; Drug: Methotrexate; Drug: Capecitabine Sponsors: University of Illinois at Chicago Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
Conditions: Breast Cancer Interventions: Drug: Cyclophosphamide; Drug: Methotrexate; Drug: Capecitabine Sponsors: University of Illinois at Chicago Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
Phase III Clinical Trial Comparing the Safety, Efficacy, and Immunogenicity of Recombinant Anti-interleukin-6 Receptor Humanized Monoclonal Antibody Injection in Combination With Methotrexate and Jamelor ® in the Treatment of Moderate to Severe Rheumatoid Arthritis
Condition: Moderate to Severe Active Rheumatoid Arthritis Interventions: Drug: HS628+MTX; Drug: Actemra +MTX Sponsor: Zhejiang Hisun Pharmaceutical Co. Ltd. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
