The Effects of Diet on Life Expectancy
It is somewhat interesting to see a careful analysis of diet and life expectancy, using the sizable UK Biobank population, that does not contain any of the words "calorie", "weight", or "obesity". The effects of calorie intake on health over the long-term are sizable, even if we focus only on mechanisms associated with the gain of weight. Visceral fat is metabolically active, generates an increased burden of senescent cells, and contributes to the chronic inflammation of aging via a range of different mechanisms. Thus one would assume that buried underneath this set of data on what it is that people eat is a more re...
Source: Fight Aging! - December 1, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Wednesday Bible Study: Job finally shuts up
 Yep. He spends the next three chapters saying, endlessly, the following:I used to be riding high, fortunate and admired, benevolent and generous.Now I ' m in the pits.If I ' d done anything wrong I could understand it.  And then, thank God, " The words of Job are ended. " It ' s long past time for this guy to STFU.29 And Job again took up his discourse, and said:2 “Oh, that I were as in the months of old,    as in the days when God watched over me;3 when his lamp shone upon my head,    and by his light I walked through darkness;4 as I was in my a...
Source: Stayin' Alive - October 18, 2023 Category: American Health Source Type: blogs

WHO Report: Tackling Hypertension Could Avert 76M Deaths Globally
Conclusion Hypertension, often referred to as the “silent killer,” isn’t just a mere health term; it’s a pressing global challenge with vast implications. As the World Health Organization’s report underscores, controlling high blood pressure is more than a matter of personal health. It’s about potentially averting millions of deaths worldwide by 2050. It’s heartening to see countries like Canada and South Korea lead the charge with effective treatment programs, offering hope and a pathway for others to follow. Yet, the contrasting statistics on sodium intake and the p...
Source: The EMT Spot - September 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Beyond the Scale: How organizations should evaluate the success of obesity management solutions
Conclusion Organizations have much to consider when evaluating obesity solutions for their population. It’s easy to be swayed by simple metrics that seem indisputable. But, in the end, outcomes like 5% weight loss and reductions in HbA1c for the majority of an eligible population are what counts. Sustainable outcomes rely on real behavior change, a careful step-therapy approach to medication, and personalized care when it comes to social determinants of health. Caitlyn Edwards, PhD, RDN, is a Senior Clinical Research Specialist at Vida Health (Source: The Health Care Blog)
Source: The Health Care Blog - September 8, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Caitlyn Edwards GLP-1 Obesity SDoH vida health Source Type: blogs

Great Food Can Improve Brain Development (Even Before Birth)
What we eat – and what our kids eat – affects so much in life: appearance, energy, cognition, focus, mood, how often we get sick, how quickly we get better, how likely we are to develop a chronic disease, and how we age. Every bite of food is either an investment in our future, a new debt we are taking out, or some of both. There are many ways to enjoy the benefits of real food. One healthy way of eating that has been studied a lot is the Mediterranean diet, a diet rich in fruits, vegetables, whole grains, beans, nuts, seeds, fish, herbs, spices, and olive oil. Red meats, processed foods, and added sugars are limited. ...
Source: Conversations with Dr Greene - September 5, 2023 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Uncategorized Mediterranean Diet Pregnancy Nutrition Top Family Nutrition Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Trials of Xenotransplantation of Pig Organs into Humans Continue
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants into terminally ill volunteers and brain dead individuals who donated their bodies to science. To learn by doing is really the only practical way by which the presently unknown problems are discovered. This trial of kidney transplantation ran for longer than prior efforts, and is a step on the path to producing a ready supply of non-human organs for transplantation, a technology that will compete with efforts to grow new organs on demands. Su...
Source: Fight Aging! - August 24, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Small Change To Diet That Lowers Blood Pressure
A dietary pattern that can reduce blood pressure effectively, even if consumed with some dairy and meat products. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 23, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Blood Pressure Source Type: blogs

poem
 Discharge InstructionsYou may have clear liquids today And nothing but salted meats tomorrowYou may lap from a bowl, sip from a hatYou may go outside and wander aimlessly In the morning in the evening but never at noonThere will be no more needles in veinsNo blood pressure cuffsNo stickers stuck to your chestYou may piss wherever you likeYou may experience a tingling behind the eyes A gutting sense of loss each time your mindReleases another thought. You may eat with your eyes closed You may hot showerYou may swim in a lakeOf slippery insouciancesYou may shave You may smile in lieu of lu...
Source: Buckeye Surgeon - August 7, 2023 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

Eggs And High Blood Pressure: Decoding The Dietary Dilemma
Conclusion In navigating the winding road of managing high blood pressure, several key points emerge. Eggs, while a source of ongoing debate, can form part of a balanced diet for most people. It’s essential, though, to consider your entire dietary pattern, emphasizing heart-healthy choices like those found in the DASH and Mediterranean diets. Avoiding processed meats and sugary breakfast options, while incorporating nutrient-dense foods, can significantly impact your blood pressure management. But remember, it’s not all about diet. A comprehensive approach, involving regular physical activity, stress mana...
Source: The EMT Spot - July 21, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

The corn is knee high
As a matter of fact, we ' ve had ample rain this year (unlike last summer) and it ' s a little more than knee high. The farm fields and gardens -- including mine -- are jumping. The point of this seeming digression is that July 4 is not really an occasion for people to contemplate the nature of the American experiment or the meaning of patriotism or anything else having to do with national purpose or identity. It marks the unofficial start of summer, and it ' s an occasion to drink too much, grill cheap (and carcinogenic) meat products, and watch fireworks displays.Contrary to Lincoln ' s famous oratory, our fathers did no...
Source: Stayin' Alive - July 4, 2023 Category: American Health Source Type: blogs

Feed the birds … twenty quid a bag …
Food for the garden birds is rather pricey. Certainly not the tuppence-a-bag of the song from Mary Poppins. Admittedly, the bags you buy are a lot more heavily laden with various seeds and grains. Anyway, discussion is ongoing in my Wild Fen Edge group about when to feed garden birds, so here are some thoughts. Birds need to eat all year round. So, I put food out all the time – mixed seed peanuts, nyjer seeds, fat balls, flutter butter. Different places in the garden, different heights if possible, near obvious perching points, higher than cat access, some out in the open. Also, not too many feeders close together to...
Source: David Bradley Sciencebase - Songs, Snaps, Science - June 28, 2023 Category: Science Authors: David Bradley Tags: Birds Source Type: blogs

Pump Up the Potassium
The element potassium plays a pivotal role in our bodies. It’s found in all our cells, where it regulates their volume and pressure. To do this, our bodies carefully control potassium levels so that the concentration is about 30 times higher inside cells than outside. Potassium works closely with sodium, which regulates the extracellular fluid volume and has a higher concentration outside cells than inside. These concentration differences create an electrochemical gradient, or a membrane potential. Potassium is the primary regulator of the pressure and volume inside cells, and it’s important for nerve transmiss...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 21, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Molecular Structures Cellular Processes Element Proteins Source Type: blogs

Can You Follow A Vegan Diet With Hypertension?
Conclusion Returning to our original question—can you follow a vegan diet with hypertension?—current research suggests a tentative ‘yes.’ With thoughtful planning and balanced nutrition, the potential benefits can outweigh the challenges. However, it’s vital to remember that managing hypertension is a multifaceted undertaking, and dietary changes should be just one part of a comprehensive lifestyle and medical management plan. Read also: Can You Consume High-Sodium Foods With Hypertension? Reference Vegetarian Diets and Blood Pressure Among White Subjects: Results from the Adventist H...
Source: The EMT Spot - June 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs