Fight Aging! Newsletter, April 18th 2022
In conclusion, our results suggest that SAH extends lifespan by inducing MetR or mimicking its downstream effects. Since the lifespan-extending effects of SAH are conserved in yeast and nematodes, and MetR extends the lifespan of many species, exposure to SAH is expected to have multiple benefits across evolutionary boundaries. Our findings offer the enticing possibility that in humans the benefits of a MetR diet can be achieved by promoting Met reduction with SAH. The use of endogenous metabolites, such as SAH, is considered safer than drugs and other substances, suggesting that it may be one of the most feasible ways to ...
Source: Fight Aging! - April 17, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Bacteria Promote Cancer Metastasis
Given the onset of a particular type of cancer, why does that cancer become a much worse prospect for only some individuals? Why are some people more prone to metastasis, for example? A perhaps underappreciated factor is the interaction of infectious agents with the tumor microenvironment, as researchers discuss here. Exposure to pathogens, and particularly persistent pathogens, may be a good explanation for many areas of medicine in which only some people bearing all of the traditional risk factors go on to develop the worst outcomes.
Microbes play a critical role in affecting cancer susceptibility and tumor prog...
Source: Fight Aging! - April 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
If You ’ ve Seen One Robot – Wait, What?
BY KIM BELLARD
If You’ve Seen One Robot – Wait, What?
We think we know robots, from the old school Robbie the Robot to the beloved R2-D2/C-3PO to the acrobatic Boston Dynamics robots or the very human-like Westworld ones. But you have to love those scientists: they keep coming up with new versions, ones that shatter our preconceptions. Two, in particular, caught my attention, in part because both expect to have health care applications, and in part because of how they’re described.
Hint: the marketing people are going to have some work to do on the names.
———–
Let’s...
Source: The Health Care Blog - April 7, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Kim Bellard robots SlimeBot Source Type: blogs
Magnetic Tentacle Robot Travels Deep into Lungs
Researchers at the University of Leeds in the UK have created a magnetic “tentacle robot” that is just 2 mm in diameter, which they hope will be able to navigate through some of the smallest airways in our lungs. At present, a bronchoscope is used to investigate the lungs, but this cannot pass into very narrow airways without an additional catheter attachment. This arrangement is cumbersome and difficult to navigate. This new technology is controlled autonomously using external magnets mounted on robotic arms and does not require X-ray imaging during the procedure. The researchers hope that the device will aid clinicia...
Source: Medgadget - March 25, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Anesthesiology Cardiology Critical Care Diagnostics Pathology Radiology Surgery Source Type: blogs
Cancer: The Popular Vitamin That Triples Risk Of Lung Disease
These popular vitamin supplements can increase the risk of developing lung cancer almost four times. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 20, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Cancer Source Type: blogs
Fight Aging! Newsletter, March 14th 2022
This study tests the feasibility of chronically elevating skeletal muscle NAD+ in mice and investigates the putative effects on mitochondrial respiratory capacity, insulin sensitivity, and gene expression. The metabolic effects of NR and PT treatment were modest. We conclude that the chronic elevation of skeletal muscle NAD+ by the intravenous injection of NR is possible but does not affect muscle respiratory capacity or insulin sensitivity in either sedentary or physically active mice. Our data have implications for NAD+ precursor supplementation regimens.
Muscle Strengthening Activities in Later Life Correlate ...
Source: Fight Aging! - March 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Muscle Strengthening Activities in Later Life Correlate with Reduced Mortality
Past studies have demonstrated reduced mortality as a result of strength training in older individuals. Muscle tissue is metabolically active, involved in a range of processes in the body, such as insulin metabolism and control of inflammation. Here this review paper, researchers note the correlation between activities that strengthen muscle and lower mortality in epidemiological data. It is worth thinking about for those of us tempted to let the exercise schedule lapse as life moves on.
Physical inactivity is a global public health problem. Regular engagement in muscle-strengthening activities (eg, resistance tra...
Source: Fight Aging! - March 8, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Long Term Data on Particulate Air Pollution and Dementia in a US Population
There is plenty of evidence for particulate air pollution to have a negative effect on long-term health, particularly those derived from Asian populations that are exposed to more coal and wood smoke than tends to be the case in the US and Western Europe. While the relative importance of the various mechanisms involved are up for debate, the most plausible are those involving raised inflammation as a result of interactions between particles and lung tissue. The chronic inflammation of aging drives near all age-related conditions, and more inflammation means more dysfunction.
As researchers note here, not all particu...
Source: Fight Aging! - March 7, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Tobacco is a painful addiction
Smoking cigarettes is well known to cause heart disease, lung cancer, and premature death. In the face of these risks of death, quality of life issues that affect smokers are often overlooked. Although some quality of life issues such as cost, cravings, inconvenience, illness, and stigma are well known, some important effects are largely unknownRead more …Tobacco is a painful addiction originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 23, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lee-flowers" rel="tag" > Lee Flowers, MD < /a > < /span > Tags: Conditions Psychiatry Source Type: blogs
Wear your mask to protect your family
Below is a story a patient shared with me about how he went from being against mask-wearing to wearing one every day. *** Last year, my mom died from stage 4 lung cancer. Before she passed, she received her transplant at this hospital, but it was too late for her. Now, I am fighting cancer.Read more …Wear your mask to protect your family originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 10, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/ton-la-jr" rel="tag" > Ton La, Jr., JD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs
The Surprisingly Sustainable Household Items You Didn ’t Know You Could Recycle
One of the biggest environmental issues we are facing today is climate change. It has an impact on every aspect of our lives, including our health and wellbeing. Recycling means fewer raw materials are required to make items, which helps reduce our carbon footprint and our contribution to climate change. A new study by packaging experts RAJA UK has uncovered just how much waste is not being recycled, and as a result, ends up in our ecosystem. Here are just a few of the ways not recycling or reusing items is having a direct impact on both our health and the world around us.
The pressures that are put on the environment...
Source: PickTheBrain | Motivation and Self Improvement - November 19, 2021 Category: Consumer Health News Authors: Erin Falconer Tags: featured self education self-improvement lifestyle pollution recycling sustainability Source Type: blogs
The rise of targeted therapies: the era of the patient-focused approach
There is an urgent need for innovation in cancer treatments. Although we ’ve seen significant progress in indications for drugs treating particular diseases, cancer research data shows that 10-year survival statistics for cancers such as esophageal and lung cancer, for instance, have shown only a 10 percent increase, while pancreatic cancer has shown no significant im provement sinceRead more …The rise of targeted therapies: the era of the patient-focused approach originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 12, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/m-yair-levy" rel="tag" > M. Yair Levy, MD < /a > < /span > Tags: Meds Oncology/Hematology Source Type: blogs
Digital Health Interests Of Pharma Giants Boehringer Ingelheim, Takeda, Astrazeneca, Amgen And Roche
With their extending reaches, resources and influence, pharmaceutical heavyweights have the potential to shape the digital health landscape to line up with their interests. And to have a better picture of where those interests lie, it is worth taking a look at what moves pharma giants are making in this sphere. With this in mind, we started a series of articles focusing on the digital health efforts of 14 global pharma companies.
The first article explored developments coming from Johnson & Johnson, Pfizer, Bayer and Novartis, while the second article investigated those coming from Merck, GlaxoSmithKline, AbbV...
Source: The Medical Futurist - November 4, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine Digital Health Research Future of Pharma sleep patient empowerment pharmaceutics roche MySugr Astra-Zeneca DTx takeda Boehringer Ingelheim Amgen digitisation Quire.ai Renalytix Eko Source Type: blogs
Fight Aging! Newsletter, October 4th 2021
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them.
Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals
https://ww...
Source: Fight Aging! - October 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Senolytics as a Potential Treatment for Precancerous Lesions
It is reasonable to think that intermittent treatment with senolytics can suppress cancer incidence by killing the senescent cells that are present in precancerous lesions, whether or not they are too small to be identified by present screening techniques. This should reduce the number of cells that can potentially go on to become cancerous, and also remove the contribution of senescent cell signaling to the growth and inflammatory status of the lesion. It should not be too challenging to prove this hypothesis in animal models, but prevention of cancer in the general sense is, unfortunately, a hard sell when it comes to cl...
Source: Fight Aging! - September 29, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
