Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: Pain Physician - April 22, 2024 Category: Anesthesiology Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

Lumbar Spinal Stenosis: Diagnosis and Management
Am Fam Physician. 2024 Apr;109(4):350-359.ABSTRACTLumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years. The pain is typica...
Source: American Family Physician - April 22, 2024 Category: Primary Care Authors: Charles W Webb Kenneth Aguirre Peter H Seidenberg Source Type: research

One-hole split endoscope versus unilateral biportal endoscopy for lumbar spinal stenosis: a retrospective propensity score study
The one-hole split endoscopy (OSE) was first proposed and clinically applied in China in 2019. The aim of this study was to compare the clinical efficacy of one-hole split endoscopy (OSE) and unilateral biport... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - April 22, 2024 Category: Orthopaedics Authors: Tusheng Li, Qiang Jiang, Wei Zhong, Tengyue Zhu, Zhengcao Lu and Yu Ding Tags: Research article Source Type: research

Manual therapists ’ appraisal of optimal non-pharmacological conservative management of patients with lumbar spinal stenosis. An international Delphi study.
Lumbar Spinal Stenosis (LSS) is a slow progressive degenerative disorder associated with chronic pain and disability. Although consensus-based international guidelines for invasive treatment of patients with LSS exist, few consensus-based guidelines for optimal conservative management strategies have been published. (Source: Journal of Bodywork and Movement Therapies)
Source: Journal of Bodywork and Movement Therapies - April 19, 2024 Category: Physiotherapy Authors: Konstantinos Prentzas, Zacharias Dimitriadis, Ren ée De Ruijter, Sionnadh McLean Source Type: research

miR-29b-3p Affects the Hypertrophy of Ligamentum Flavum in Lumbar Spinal Stenosis and its Mechanism
Biochem Genet. 2024 Apr 16. doi: 10.1007/s10528-024-10811-8. Online ahead of print.ABSTRACTTo explore the effect of miR-29b-3p on fibrosis and hypertrophy of ligamentum flavum (LF) in lumbar spinal stenosis (LSS) and its underlying mechanism. Patients with LSS and lumbar disc herniation (LDH) (control) undergoing posterior lumbar laminectomy were included in this study. Human LF samples were obtained for LF cell isolation, RNA, and protein extraction. Histomorphological analysis of LF was performed using hematoxylin-eosin (HE) staining. After isolation, culture, and transfection of primary LF cells, different transfection ...
Source: Biochemical Genetics - April 16, 2024 Category: Genetics & Stem Cells Authors: Hongjie Zhang Zhixiong Hong Zehua Jiang Wei Hu Jiashao Hu Rusen Zhu Source Type: research

miR-29b-3p Affects the Hypertrophy of Ligamentum Flavum in Lumbar Spinal Stenosis and its Mechanism
Biochem Genet. 2024 Apr 16. doi: 10.1007/s10528-024-10811-8. Online ahead of print.ABSTRACTTo explore the effect of miR-29b-3p on fibrosis and hypertrophy of ligamentum flavum (LF) in lumbar spinal stenosis (LSS) and its underlying mechanism. Patients with LSS and lumbar disc herniation (LDH) (control) undergoing posterior lumbar laminectomy were included in this study. Human LF samples were obtained for LF cell isolation, RNA, and protein extraction. Histomorphological analysis of LF was performed using hematoxylin-eosin (HE) staining. After isolation, culture, and transfection of primary LF cells, different transfection ...
Source: Biochemical Genetics - April 16, 2024 Category: Genetics & Stem Cells Authors: Hongjie Zhang Zhixiong Hong Zehua Jiang Wei Hu Jiashao Hu Rusen Zhu Source Type: research

Dural Sac Cross-sectional area change from preoperatively and up to 2 years after decompressive surgery for central lumbar spinal stenosis: investigation of operated levels, data from the NORDSTEN study
ConclusionThe spinal canal area after lumbar decompressive surgery for lumbar spinal stenosis increased from baseline to 3 months after surgery and remained thereafter unchanged 2 years postoperatively. (Source: European Spine Journal)
Source: European Spine Journal - April 8, 2024 Category: Orthopaedics Source Type: research