Curvature mediated source and sink effects on the genesis of premature ventricular complexes in long QT syndrome
In conclusion, besides the increase of RG and occurrence of EADs caused by QT prolongation, the geometry of the RG border plays important roles in PVC genesis, which can greatly increase the risk of arrhythmias in cardiac diseases.PMID:38551483 | DOI:10.1152/ajpheart.00004.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 29, 2024 Category: Physiology Authors: Yuhao Zhang Zhaoyang Zhang Zhilin Qu Source Type: research

Curvature mediated source and sink effects on the genesis of premature ventricular complexes in long QT syndrome
In conclusion, besides the increase of RG and occurrence of EADs caused by QT prolongation, the geometry of the RG border plays important roles in PVC genesis, which can greatly increase the risk of arrhythmias in cardiac diseases.PMID:38551483 | DOI:10.1152/ajpheart.00004.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 29, 2024 Category: Physiology Authors: Yuhao Zhang Zhaoyang Zhang Zhilin Qu Source Type: research

Curvature mediated source and sink effects on the genesis of premature ventricular complexes in long QT syndrome
In conclusion, besides the increase of RG and occurrence of EADs caused by QT prolongation, the geometry of the RG border plays important roles in PVC genesis, which can greatly increase the risk of arrhythmias in cardiac diseases.PMID:38551483 | DOI:10.1152/ajpheart.00004.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 29, 2024 Category: Physiology Authors: Yuhao Zhang Zhaoyang Zhang Zhilin Qu Source Type: research

Curvature mediated source and sink effects on the genesis of premature ventricular complexes in long QT syndrome
In conclusion, besides the increase of RG and occurrence of EADs caused by QT prolongation, the geometry of the RG border plays important roles in PVC genesis, which can greatly increase the risk of arrhythmias in cardiac diseases.PMID:38551483 | DOI:10.1152/ajpheart.00004.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 29, 2024 Category: Physiology Authors: Yuhao Zhang Zhaoyang Zhang Zhilin Qu Source Type: research

Generation of KCNH2 heterozygous knockout induced pluripotent stem cell (iPSC) line (Long and Short QT Syndrome)
In this study, we generated induced pluripotent stem cells (iPSC) from a healthy individual by electroporation of peripheral blood mononuclear cells and generated a KCNH2 heterozygous knockout human iPSC line via CRISPR/Cas9 gene editing. The resulting iPSCs had a normal karyotype, were free of genomically integrated epitomal plasmids, expressed pluripotency markers, and maintained trilineage differentiation potential.PMID:38547667 | DOI:10.1016/j.scr.2024.103400 (Source: Cell Research)
Source: Cell Research - March 28, 2024 Category: Cytology Authors: Baiqiang Wang Qian Ren Xiaomeng Cui Wei Shan Xiangge Guo Xumeng Wang Jiaxuan Wang Yanting Li Guipeng An Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research

Pregnancy Management in a Patient with Long QT Syndrome Type 2 (LQT2) carrier of the variant KCNH2: Trp100X
We present a case report of a 30-year-old pregnant woman with known long QT syndrome Type 2 (LQT2) and discuss the management in cardiological practice.PMID:38536194 (Source: Praxis)
Source: Praxis - March 27, 2024 Category: General Medicine Authors: Greta Hametner Martin Osranek Corinna Brunckhorst Argelia Medeiros Domingo Source Type: research